PREGNENOLONE SUCCINATE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 6LN4W6JJK6

Structure
InChI Key OZZAYJQNMKMUSD-DMISRAGPSA-N
Smile CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)CCC(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
InChI=1S/C25H36O5/c1-15(26)19-6-7-20-18-5-4-16-14-17(30-23(29)9-8-22(27)28)10-12-24(16,2)21(18)11-13-25(19,20)3/h4,17-21H,5-14H2,1-3H3,(H,27,28)/t17-,18-,19+,20-,21-,24-,25+/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H36O5
Molecular Weight 416.56
AlogP 4.93
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 5.0
Polar Surface Area 80.67
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 30.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Ion channel Ligand-gated ion channel Ionotropic glutamate receptor NMDA receptor
27600 - - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Schizophrenia 2 D012559 ClinicalTrials
Autistic Disorder 2 D001321 ClinicalTrials
Wounds and Injuries 2 D014947 ClinicalTrials
Substance Withdrawal Syndrome 2 D013375 ClinicalTrials
Low Back Pain 2 D017116 ClinicalTrials
Stress Disorders, Post-Traumatic 2 D013313 ClinicalTrials
Marijuana Abuse 2 D002189 ClinicalTrials
Psychotic Disorders 2 D011618 ClinicalTrials
Alcoholism 0 D000437 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 135355
ChEMBL CHEMBL2105373
DrugCentral 2256
EPA CompTox DTXSID40196673
FDA SRS 6LN4W6JJK6
PubChem 10070529
SureChEMBL SCHEMBL667221
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