Synonyms: | |
Status: | Phase 2 |
Entry Type: | Small molecule |
Molecule Category: | UNKNOWN |
UNII: | 8KFO2187CP |
InChI Key | KURQKNMKCGYWRJ-HNNXBMFYSA-N |
---|---|
Smile | |
InChI |
|
Property Name | Value |
---|---|
Molecular Formula | C20H21N7O3 |
Molecular Weight | 407.43 |
AlogP | 2.12 |
Hydrogen Bond Acceptor | 10.0 |
Hydrogen Bond Donor | 1.0 |
Number of Rotational Bond | 6.0 |
Polar Surface Area | 127.0 |
Molecular species | NEUTRAL |
Aromatic Rings | 4.0 |
Heavy Atoms | 30.0 |
Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
---|---|---|---|---|---|---|
Membrane receptor
Family A G protein-coupled receptor
Small molecule receptor (family A GPCR)
Nucleotide-like receptor (family A GPCR)
Adenosine receptor
|
- | 17-70 | - | 192 | - |
Mesh Heading | Maximum Phase | Mesh ID | Reference |
---|---|---|---|
Attention Deficit Disorder with Hyperactivity | 1 | D001289 | ClinicalTrials |
Parkinson Disease | 1 | D010300 | ClinicalTrials |
Multiple Myeloma | 1 | D009101 | ClinicalTrials |
Carcinoma, Non-Small-Cell Lung | 1 | D002289 | ClinicalTrials |
Resources | Reference |
---|---|
ChEMBL | CHEMBL4297184 |
DrugBank | DB16125 |
FDA SRS | 8KFO2187CP |
Guide to Pharmacology | 10190 |
PubChem | 44537963 |
SureChEMBL | SCHEMBL536782 |