FIBOFLAPON SODIUM

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 75YS00XOG3

Structure
InChI Key NOJNFULGOQGBKB-UHFFFAOYSA-M
Smile CCOc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)[O-])c(SC(C)(C)C)c4cc(OCc5ccc(C)cn5)ccc43)cc2)cn1.[Na+]
InChI
InChI=1S/C38H43N3O4S.Na/c1-8-44-34-18-14-28(22-40-34)27-12-10-26(11-13-27)23-41-32-17-16-30(45-24-29-15-9-25(2)21-39-29)19-31(32)35(46-37(3,4)5)33(41)20-38(6,7)36(42)43;/h9-19,21-22H,8,20,23-24H2,1-7H3,(H,42,43);/q;+1/p-1

Physicochemical Descriptors

Property Name Value
Molecular Formula C38H42N3NaO4S
Molecular Weight 659.83
AlogP 8.98
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 12.0
Polar Surface Area 86.47
Molecular species ACID
Aromatic Rings 5.0
Heavy Atoms 46.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR 5-lipoxygenase activating protein inhibitor PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Asthma 2 D001249 ClinicalTrials
Cystic Fibrosis 2 D003550 ClinicalTrials
HIV-Associated Lipodystrophy Syndrome 1 D039682 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL1922673
EPA CompTox DTXSID50152523
FDA SRS 75YS00XOG3
PubChem 44473150
SureChEMBL SCHEMBL1254527
CONTENTS