SULOCTIDIL

Search structure
Synonyms:
Status: Approved (1979)
Entry Type: Small molecule
Molecule Category: UNKNOWN
ATC: C04AX19
UNII: XV1N1XY17K

Structure
InChI Key BFCDFTHTSVTWOG-UHFFFAOYSA-N
Smile CCCCCCCCNC(C)C(O)c1ccc(SC(C)C)cc1
InChI
InChI=1S/C20H35NOS/c1-5-6-7-8-9-10-15-21-17(4)20(22)18-11-13-19(14-12-18)23-16(2)3/h11-14,16-17,20-22H,5-10,15H2,1-4H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C20H35NOS
Molecular Weight 337.57
AlogP 5.56
Hydrogen Bond Acceptor 3.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 12.0
Polar Surface Area 32.26
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 23.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Voltage-gated calcium channel blocker
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - -
Enzyme Kinase Protein Kinase TK protein kinase group Tyrosine protein kinase EGFR family
- 794.4 - - -
Enzyme Kinase Protein Kinase TK protein kinase group Tyrosine protein kinase Src family
- 722.1 - - -
Enzyme Transferase
- - - - 24.82
Epigenetic regulator Eraser Histone deacetylase HDAC class IIb
- - - - 1.37-2.87
Membrane receptor Family A G protein-coupled receptor Peptide receptor (family A GPCR) Short peptide receptor (family A GPCR) Neurokinin receptor
- 6792.9 - 2264.3 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Acetylcholine receptor
- 4486.8 - 1085 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
- 2023.2 - 3747.2 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Dopamine receptor
- 2103.9 - 714.5 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Histamine receptor
- 108.1 - 2475.9 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Serotonin receptor
- 543.5 - 310.6 -
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Nucleotide-like receptor (family A GPCR) Adenosine receptor
- 3705.8 - 2094.6 -
Membrane receptor
- 108.1 - 1085 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC06 neurotransmitter transporter family
- 1253.2 - 1388.8 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 108.69

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Cross References

Resources Reference
ChEBI 91639
ChEMBL CHEMBL404849
DrugCentral 2536
EPA CompTox DTXSID4045638
FDA SRS XV1N1XY17K
PubChem 5354
SureChEMBL SCHEMBL23974
CONTENTS