LEVONORDEFRIN

Search structure
Synonyms:
Status: Approved (1960)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: V008L6478D

Structure
InChI Key GEFQWZLICWMTKF-CDUCUWFYSA-N
Smile C[C@H](N)[C@H](O)c1ccc(O)c(O)c1
InChI
InChI=1S/C9H13NO3/c1-5(10)9(13)6-2-3-7(11)8(12)4-6/h2-5,9,11-13H,10H2,1H3/t5-,9-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C9H13NO3
Molecular Weight 183.21
AlogP 0.48
Hydrogen Bond Acceptor 4.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 2.0
Polar Surface Area 86.71
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 13.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Adrenergic receptor alpha-2 agonist ISBN Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
776 - - 3600-9221 -
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 59

Cross References

Resources Reference
ChEBI 10304
ChEMBL CHEMBL677
DrugBank DB06707
DrugCentral 4482
EPA CompTox DTXSID6046349
FDA SRS V008L6478D
Human Metabolome Database HMDB0015652
Guide to Pharmacology 508
KEGG C11768
PharmGKB PA165958380
PubChem 164739
SureChEMBL SCHEMBL119171
ZINC ZINC000000034157
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