CYC-065

Search structure
Synonyms:
Status: Phase 1
Entry Type: Unknown
Molecule Category: UNKNOWN
UNII: YET2XNU791

Physicochemical Descriptors

Property Name Value
Molecular Formula C21H31N7O
Molecular Weight 397.53
AlogP 3.6
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 8.0
Polar Surface Area 100.78
Molecular species None
Aromatic Rings 3.0
Heavy Atoms 29.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase CDK family CMGC protein kinase CDC2 subfamily
- 4.5-90 - 2.3 -
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase CDK family CMGC protein kinase CDK5 subfamily
- 21-23 - - -
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase CDK family CMGC protein kinase CDK7 subfamily
- 193 - - -
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase CDK family CMGC protein kinase CDK9 subfamily
- 13.4-26 - - -
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase GSK family
- 11100 - - -
Enzyme Kinase Protein Kinase CMGC protein kinase group CMGC protein kinase MAPK family
- 385.9 - - -
Enzyme Kinase Protein Kinase CMGC protein kinase group
- 13.4-26 - 2.3 -
Enzyme Kinase Protein Kinase Other protein kinase group Other protein kinase CAMKK family Other protein kinase Meta subfamily
- 13200 - - -
Enzyme Kinase Protein kinase regulatory subunit
- 21 - - -
Enzyme
- 13.4-26 - 2.3 -
Other cytosolic protein
- 13.4-26 - 2.3 -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Leukemia, Lymphocytic, Chronic, B-Cell 1 D015451 ClinicalTrials
Lymphoma 1 D008223 ClinicalTrials
Neoplasms 1 D009369 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297930
FDA SRS YET2XNU791
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