PRONETALOL

Search structure
Synonyms:
Status: Approved
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: XBP4RT1IMQ

Structure
InChI Key HRSANNODOVBCST-UHFFFAOYSA-N
Smile CC(C)NCC(O)c1ccc2ccccc2c1
InChI
InChI=1S/C15H19NO/c1-11(2)16-10-15(17)14-8-7-12-5-3-4-6-13(12)9-14/h3-9,11,15-17H,10H2,1-2H3

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H19NO
Molecular Weight 229.32
AlogP 2.87
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 4.0
Polar Surface Area 32.26
Molecular species BASE
Aromatic Rings 2.0
Heavy Atoms 17.0

Pharmacology

Action Mechanism of Action Reference
ANTAGONIST Beta-1 adrenergic receptor antagonist PubMed PubMed
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Membrane receptor Family A G protein-coupled receptor Small molecule receptor (family A GPCR) Monoamine receptor Adrenergic receptor
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Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 8463
ChEMBL CHEMBL16476
DrugCentral 2289
EPA CompTox DTXSID8021193
FDA SRS XBP4RT1IMQ
KEGG C11707
PubChem 4930
SureChEMBL SCHEMBL78996
CONTENTS