GLUCONOLACTONE

Search structure


Synonyms:	.delta.-d-gluconolactone Delta-gluconolactone D-gluconic acid .delta.-lactone D-gluconic acid delta-lactone D-glucono-1,5-lactone E-575 E575 Fujiglucon Glucono .delta. lactone Glucono .delta.-lactone Glucono delta-lactone Glucono-delta-lactone Gluconolactone INS-575 INS NO.575 Lysactone NSC-34393 NSC-758238 Riken lactone
Status:	Approved (1990)
Entry Type:	Small molecule
Molecule Category:	UNKNOWN
UNII:	WQ29KQ9POT

Structure


InChI Key	PHOQVHQSTUBQQK-SQOUGZDYSA-N
Smile	O=C1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
InChI	InChI=1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1

Physicochemical Descriptors

Property Name	Value
Molecular Formula	C6H10O6
Molecular Weight	178.14
AlogP	-3.01
Hydrogen Bond Acceptor	6.0
Hydrogen Bond Donor	4.0
Number of Rotational Bond	1.0
Polar Surface Area	107.22
Molecular species	NEUTRAL
Aromatic Rings	0.0
Heavy Atoms	12.0

Pharmacology

Targets	EC50(nM)	IC50(nM)	Kd(nM)	Ki(nM)	Inhibition(%)
Enzyme	-	-	-	30000	-
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides	-	-	-	-	82

Cross References

Resources	Reference
ChEBI	16217
ChEMBL	CHEMBL1200829
DrugBank	DB04564
DrugCentral	5144
EPA CompTox	DTXSID0026549
FDA SRS	WQ29KQ9POT
Human Metabolome Database	HMDB0000150
KEGG	C00198
PDB	LGC
PubChem	7027
SureChEMBL	SCHEMBL15320
ZINC	ZINC000002539702

CONTENTS