TIAPRIDE HYDROCHLORIDE

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 25N106WEDO

Structure
InChI Key OTFDPNXIVHBTKW-UHFFFAOYSA-N
Smile CCN(CC)CCNC(=O)c1cc(S(C)(=O)=O)ccc1OC.Cl
InChI
InChI=1S/C15H24N2O4S.ClH/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3;/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18);1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C15H25ClN2O4S
Molecular Weight 364.9
AlogP 1.17
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 8.0
Polar Surface Area 75.71
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 22.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 106

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Huntington Disease 3 D006816 ClinicalTrials

Cross References

Resources Reference
ChEBI 32220
ChEMBL CHEMBL1256772
EPA CompTox DTXSID4045210
FDA SRS 25N106WEDO
PubChem 39855
SureChEMBL SCHEMBL355315
CONTENTS