| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 78G6MP5PZ5 |
Structure
| InChI Key | IRTDIKMSKMREGO-OAHLLOKOSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C22H24N4O4 |
| Molecular Weight | 408.46 |
| AlogP | 2.71 |
| Hydrogen Bond Acceptor | 7.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 5.0 |
| Polar Surface Area | 96.17 |
| Molecular species | ACID |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 30.0 |
Pharmacology
| Action | Mechanism of Action | Reference |
|---|---|---|
| INHIBITOR | PI3-kinase class I inhibitor | PubMed |
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Transferase
|
- | 10-40 | - | - | - |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 91359 |
| ChEMBL | CHEMBL2165191 |
| DrugBank | DB14980 |
| EPA CompTox | DTXSID00657619 |
| FDA SRS | 78G6MP5PZ5 |
| Guide to Pharmacology | 8059 |
| PDB | A82 |
| PubChem | 44137675 |
| SureChEMBL | SCHEMBL1812377 |
| ZINC | ZINC000038628584 |
CONTENTS