DORZAGLIATIN

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UKNOWN
UNII: X59W6980E8

Structure
InChI Key HMUMWSORCUWQJO-QAPCUYQASA-N
Smile CC(C)C[C@@H](C(=O)Nc1ccn(C[C@@H](O)CO)n1)N1CC(Oc2ccccc2Cl)=CC1=O
InChI
InChI=1S/C22H27ClN4O5/c1-14(2)9-18(22(31)24-20-7-8-26(25-20)11-15(29)13-28)27-12-16(10-21(27)30)32-19-6-4-3-5-17(19)23/h3-8,10,14-15,18,28-29H,9,11-13H2,1-2H3,(H,24,25,31)/t15-,18+/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C22H27ClN4O5
Molecular Weight 462.93
AlogP 2.05
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 10.0
Polar Surface Area 116.92
Molecular species NEUTRAL
Aromatic Rings 2.0
Heavy Atoms 32.0

Pharmacology

Action Mechanism of Action Reference
ACTIVATOR Hexokinase type IV activator PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Diabetes Mellitus, Type 2 3 D003924 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4297508
DrugBank DB15123
FDA SRS X59W6980E8
SureChEMBL SCHEMBL1079619
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