TOCILIZUMAB

Search structure
Synonyms:
MRA
Status: Approved (2005)
Entry Type: Antibody
Molecule Category: UNKNOWN
ATC: L04AC07
UNII: I031V2H011

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Interleukin-6 receptor alpha subunit inhibitor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Severe Acute Respiratory Syndrome 4 D045169 ClinicalTrials
Severe Acute Respiratory Syndrome 4 D045169 ClinicalTrials
Arthritis, Juvenile 4 D001171 ClinicalTrials
Lymphoma, Non-Hodgkin 3 D008228 ClinicalTrials
Epilepsy 3 D004827 ClinicalTrials
Influenza, Human 3 D007251 ClinicalTrials
Takayasu Arteritis 3 D013625 ClinicalTrials
Lymphoma 3 D008223 ClinicalTrials
Lymphoma, Large B-Cell, Diffuse 3 D016403 ClinicalTrials
Spondylitis, Ankylosing 3 D013167 ClinicalTrials
Polymyalgia Rheumatica 3 D011111 ClinicalTrials
Pneumonia 3 D011014 ClinicalTrials
Sepsis 3 D018805 ClinicalTrials
Depressive Disorder, Major 2 D003865 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Hypertension, Pulmonary 2 D006976 ClinicalTrials
Uveitis 2 D014605 ClinicalTrials
Dermatomyositis 2 D003882 ClinicalTrials
Leukemia 2 D007938 ClinicalTrials
Multiple Myeloma 2 D009101 ClinicalTrials
Pancreatic Neoplasms 2 D010190 ClinicalTrials
Behcet Syndrome 2 D001528 ClinicalTrials
Neuromyelitis Optica 2 D009471 ClinicalTrials
Still's Disease, Adult-Onset 2 D016706 ClinicalTrials
Erdheim-Chester Disease 2 D031249 ClinicalTrials
Polychondritis, Relapsing 2 D011081 ClinicalTrials
Neoplasms 2 D009369 ClinicalTrials
Melanoma 2 D008545 ClinicalTrials
Non-ST Elevated Myocardial Infarction 2 D000072658 ClinicalTrials
Prostatic Neoplasms 2 D011471 ClinicalTrials
Graft vs Host Disease 2 D006086 ClinicalTrials
Lymphohistiocytosis, Hemophagocytic 2 D051359 ClinicalTrials
Castleman Disease 2 D005871 ClinicalTrials
Hematologic Neoplasms 2 D019337 ClinicalTrials
Respiratory Distress Syndrome 2 D012128 ClinicalTrials
Fever 2 D005334 ClinicalTrials
Schnitzler Syndrome 2 D019873 ClinicalTrials
Graves Ophthalmopathy 2 D049970 ClinicalTrials
Lung Diseases 2 D008171 ClinicalTrials
Myasthenia Gravis 2 D009157 ClinicalTrials
Fibrous Dysplasia of Bone 2 D005357 ClinicalTrials
Amyotrophic Lateral Sclerosis 2 D000690 ClinicalTrials
Diabetes Mellitus, Type 1 2 D003922 ClinicalTrials
Familial Mediterranean Fever 2 D010505 ClinicalTrials
Lymphoma, Mantle-Cell 2 D020522 ClinicalTrials
Astrocytoma 2 D001254 ClinicalTrials
Virus Diseases 2 D014777 ClinicalTrials
Polymyositis 2 D017285 ClinicalTrials
Motor Neuron Disease 2 D016472 ClinicalTrials
Prostatic Neoplasms, Castration-Resistant 2 D064129 ClinicalTrials
Pneumonia, Viral 2 D011024 ClinicalTrials
Macrophage Activation Syndrome 2 D055501 ClinicalTrials
Breast Neoplasms 2 D001943 ClinicalTrials
Urinary Bladder Neoplasms 1 D001749 ClinicalTrials
Leukemia, Myeloid, Acute 1 D015470 ClinicalTrials
HIV Infections 1 D015658 ClinicalTrials
Carcinoma, Non-Small-Cell Lung 1 D002289 ClinicalTrials
Carcinoma, Hepatocellular 1 D006528 ClinicalTrials
Ovarian Neoplasms 1 D010051 ClinicalTrials
Liver Neoplasms 1 D008113 ClinicalTrials
Colorectal Neoplasms 1 D015179 ClinicalTrials
Schizophrenia 1 D012559 ClinicalTrials
Lymphoma, Follicular 1 D008224 ClinicalTrials
Renal Insufficiency, Chronic 1 D051436 ClinicalTrials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 1 D054198 ClinicalTrials
Lymphoma, Follicular 1 D008224 ClinicalTrials
Leukemia, Biphenotypic, Acute 1 D015456 ClinicalTrials
Panuveitis 1 D015864 ClinicalTrials
Small Cell Lung Carcinoma 1 D055752 ClinicalTrials
Uveitis, Posterior 1 D015866 ClinicalTrials
Leukemia, Lymphocytic, Chronic, B-Cell 1 D015451 ClinicalTrials
Lymphoma, B-Cell 1 D016393 ClinicalTrials
Uveitis, Intermediate 1 D015867 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL1237022
FDA SRS I031V2H011
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