| Synonyms: | |
| Status: | Approved (1982) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | R05DA09 |
| UNII: | 7355X3ROTS |
Structure
| InChI Key | MKXZASYAUGDDCJ-NJAFHUGGSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C18H25NO |
| Molecular Weight | 271.4 |
| AlogP | 3.38 |
| Hydrogen Bond Acceptor | 2.0 |
| Hydrogen Bond Donor | 0.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 12.47 |
| Molecular species | BASE |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 20.0 |
Pharmacology
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Cough | 4 | D003371 | ClinicalTrials |
| Amyotrophic Lateral Sclerosis | 3 | D000690 | ClinicalTrials |
| Opioid-Related Disorders | 3 | D009293 | ClinicalTrials |
| Multiple Sclerosis, Relapsing-Remitting | 3 | D020529 | ClinicalTrials |
| Proteinuria | 3 | D011507 | ClinicalTrials |
| Depressive Disorder, Treatment-Resistant | 3 | D061218 | ClinicalTrials |
| Bipolar Disorder | 3 | D001714 | ClinicalTrials |
| Multiple Sclerosis | 3 | D009103 | ClinicalTrials |
| Rett Syndrome | 3 | D015518 | ClinicalTrials |
| Depressive Disorder, Major | 2 | D003865 | ClinicalTrials |
| Peripheral Nervous System Diseases | 2 | D010523 | ClinicalTrials |
| Neuralgia | 2 | D009437 | ClinicalTrials |
| Irritable Bowel Syndrome | 2 | D043183 | ClinicalTrials |
| Autistic Disorder | 2 | D001321 | ClinicalTrials |
| Diabetic Neuropathies | 2 | D003929 | ClinicalTrials |
| Hypertrophy | 2 | D006984 | ClinicalTrials |
| Fibromyalgia | 2 | D005356 | ClinicalTrials |
| Neuralgia | 2 | D009437 | ClinicalTrials |
| Substance-Related Disorders | 2 | D019966 | ClinicalTrials |
| Schizophrenia | 2 | D012559 | ClinicalTrials |
| Diabetes Mellitus, Type 2 | 2 | D003924 | ClinicalTrials |
| Parkinson Disease | 2 | D010300 | ClinicalTrials |
| Neurodegenerative Diseases | 2 | D019636 | ClinicalTrials |
| Trypanosomiasis | 1 | D014352 | ClinicalTrials |
| Malaria | 1 | D008288 | ClinicalTrials |
| Common Cold | 1 | D003139 | ClinicalTrials |
| Alzheimer Disease | 1 | D000544 | ClinicalTrials |
| HIV Infections | 1 | D015658 | ClinicalTrials |
| Neoplasm Metastasis | 1 | D009362 | ClinicalTrials |
| Crohn Disease | 1 | D003424 | ClinicalTrials |
| Cognitive Dysfunction | 1 | D060825 | ClinicalTrials |
| Psoriasis | 1 | D011565 | ClinicalTrials |
| Neoplasms | 1 | D009369 | ClinicalTrials |
| Melanoma | 1 | D008545 | ClinicalTrials |
| Mitochondrial Diseases | 1 | D028361 | ClinicalTrials |
| Melanoma | 1 | D008545 | ClinicalTrials |
| Voice Disorders | 1 | D014832 | ClinicalTrials |
| Cytomegalovirus Infections | 1 | D003586 | ClinicalTrials |
| Prostatic Neoplasms, Castration-Resistant | 1 | D064129 | ClinicalTrials |
| Colitis, Ulcerative | 1 | D003093 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 4470 |
| ChEMBL | CHEMBL52440 |
| DrugBank | DB00514 |
| DrugCentral | 842 |
| EPA CompTox | DTXSID3022908 |
| FDA SRS | 7355X3ROTS |
| Human Metabolome Database | HMDB01920 |
| Guide to Pharmacology | 6953 |
| PharmGKB | PA449273 |
| PubChem | 5360696 |
| SureChEMBL | SCHEMBL29949 |
| ZINC | ZINC000003201907 |
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