SAMIDORPHAN L-MALATE

Search structure
Synonyms:
Status: Approved (2021)
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: 0AJQ5N56E0

Structure
InChI Key RARHXUAUPNYAJF-QSYGGRRVSA-N
Smile NC(=O)c1ccc2c(c1O)[C@]13CCN(CC4CC4)[C@H](C2)[C@]1(O)CCC(=O)C3.O=C(O)C[C@H](O)C(=O)O
InChI
InChI=1S/C21H26N2O4.C4H6O5/c22-19(26)15-4-3-13-9-16-21(27)6-5-14(24)10-20(21,17(13)18(15)25)7-8-23(16)11-12-1-2-12;5-2(4(8)9)1-3(6)7/h3-4,12,16,25,27H,1-2,5-11H2,(H2,22,26);2,5H,1H2,(H,6,7)(H,8,9)/t16-,20-,21-;2-/m10/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C25H32N2O9
Molecular Weight 504.54
AlogP 1.25
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 3.0
Number of Rotational Bond 3.0
Polar Surface Area 103.86
Molecular species BASE
Aromatic Rings 1.0
Heavy Atoms 27.0

Pharmacology

Action Mechanism of Action Reference
PARTIAL AGONIST Delta opioid receptor partial agonist

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Bipolar Disorder 4 D001714 FDA
Schizophrenia 4 D012559 FDA

Related Entries

Scaffolds

Cross References

Resources Reference
ChEMBL CHEMBL2105749
FDA SRS 0AJQ5N56E0
PubChem 53362094
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