CLODRONATE DISODIUM

Search structure
Synonyms:
Status: Phase 3
Entry Type: Small molecule
Molecule Category: UNKNOWN
UNII: N030400H8J

Structure
InChI Key HJKBJIYDJLVSAO-UHFFFAOYSA-L
Smile O=P([O-])(O)C(Cl)(Cl)P(=O)([O-])O.[Na+].[Na+]
InChI
InChI=1S/CH4Cl2O6P2.2Na/c2-1(3,10(4,5)6)11(7,8)9;;/h(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2

Physicochemical Descriptors

Property Name Value
Molecular Formula CH2Cl2Na2O6P2
Molecular Weight 288.86
AlogP 0.43
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 2.0
Polar Surface Area 115.06
Molecular species ACID
Aromatic Rings 0.0
Heavy Atoms 11.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Transferase
- - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Pain 3 D010146 ClinicalTrials
Breast Neoplasms 3 D001943 ClinicalTrials
Osteoarthritis 2 D010003 ClinicalTrials

Cross References

Resources Reference
ChEBI 59586
ChEMBL CHEMBL1520188
EPA CompTox DTXSID3045225
FDA SRS N030400H8J
PubChem 31195
SureChEMBL SCHEMBL28438
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