| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UNKNOWN |
| UNII: | 8V9YR09EF3 |
Structure
| InChI Key | LXFOLMYKSYSZQS-LURJZOHASA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C30H42N8O3 |
| Molecular Weight | 562.72 |
| AlogP | 3.32 |
| Hydrogen Bond Acceptor | 10.0 |
| Hydrogen Bond Donor | 4.0 |
| Number of Rotational Bond | 8.0 |
| Polar Surface Area | 151.23 |
| Molecular species | BASE |
| Aromatic Rings | 4.0 |
| Heavy Atoms | 41.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Epigenetic regulator
Writer
Protein methyltransferase
|
- | 3-52 | - | 0-0 | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1 | D054198 | ClinicalTrials |
| Leukemia, Myeloid, Acute | 1 | D015470 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL3414626 |
| DrugBank | DB12920 |
| FDA SRS | 8V9YR09EF3 |
| Guide to Pharmacology | 7019 |
| PDB | EP6 |
| SureChEMBL | SCHEMBL10248515 |
| ZINC | ZINC000168212088 |
CONTENTS