NITRIC OXIDE

Search structure
Synonyms:
Status: Approved (1999)
Entry Type: Small molecule
Molecule Category: UKNOWN
ATC: R07AX01
UNII: 31C4KY9ESH

Structure
InChI Key MWUXSHHQAYIFBG-UHFFFAOYSA-N
Smile [N]=O
InChI
InChI=1S/NO/c1-2

Physicochemical Descriptors

Property Name Value
Molecular Formula NO
Molecular Weight 30.01
AlogP -0.45
Hydrogen Bond Acceptor 1.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 0.0
Polar Surface Area 39.37
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 2.0

Pharmacology

Action Mechanism of Action Reference
ACTIVATOR Soluble guanylate cyclase activator DailyMed Wikipedia

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Respiratory Insufficiency 4 D012131 ClinicalTrials
Hypertension, Pulmonary 4 D006976 ClinicalTrials
Bronchopulmonary Dysplasia 3 D001997 ClinicalTrials
Leishmaniasis, Cutaneous 3 D016773 ClinicalTrials
Bronchiolitis 3 D001988 ClinicalTrials
Lung Diseases 3 D008171 ClinicalTrials
Reperfusion Injury 3 D015427 ClinicalTrials
Hernias, Diaphragmatic, Congenital 3 D065630 ClinicalTrials
Respiratory Distress Syndrome 3 D012128 ClinicalTrials
Diabetic Foot 3 D017719 ClinicalTrials
Acute Kidney Injury 3 D058186 ClinicalTrials
Sepsis 3 D018805 ClinicalTrials
Pneumonia 3 D011014 ClinicalTrials
Premature Birth 3 D047928 ClinicalTrials
Hypoxia 3 D000860 ClinicalTrials
Respiratory Distress Syndrome, Newborn 3 D012127 ClinicalTrials
Persistent Fetal Circulation Syndrome 3 D010547 ClinicalTrials
Pneumonia, Aspiration 3 D011015 ClinicalTrials
Brain Injuries 3 D001930 ClinicalTrials
Hypoxia 3 D000860 ClinicalTrials
Stroke 2 D020521 ClinicalTrials
Myocardial Ischemia 2 D017202 ClinicalTrials
Tinea Pedis 2 D014008 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Inflammation 2 D007249 ClinicalTrials
Severe Acute Respiratory Syndrome 2 D045169 ClinicalTrials
Infections 2 D007239 ClinicalTrials
Death, Sudden, Cardiac 2 D016757 ClinicalTrials
Myocardial Infarction 2 D009203 ClinicalTrials
Skin Ulcer 2 D012883 ClinicalTrials
Varicose Ulcer 2 D014647 ClinicalTrials
ST Elevation Myocardial Infarction 2 D000072657 ClinicalTrials
Neuralgia 2 D009437 ClinicalTrials
Dyspnea 2 D004417 ClinicalTrials
Cystic Fibrosis 2 D003550 ClinicalTrials
Heart Failure 2 D006333 ClinicalTrials
Sinusitis 2 D012852 ClinicalTrials
Anemia, Sickle Cell 2 D000755 ClinicalTrials
Malaria 2 D008288 ClinicalTrials
Pneumonia, Viral 2 D011024 ClinicalTrials
Opioid-Related Disorders 2 D009293 ClinicalTrials
Pulmonary Embolism 2 D011655 ClinicalTrials
Colorectal Neoplasms 1 D015179 ClinicalTrials
Anemia 1 D000740 ClinicalTrials
Pulmonary Disease, Chronic Obstructive 1 D029424 ClinicalTrials
Pressure Ulcer 1 D003668 ClinicalTrials
Brain Ischemia 1 D002545 ClinicalTrials
Heart Arrest 0 D006323 ClinicalTrials

Cross References

Resources Reference
ChEBI 16480
ChEMBL CHEMBL1200689
DrugBank DB00435
DrugCentral 1948
EPA CompTox DTXSID1020938
FDA SRS 31C4KY9ESH
Human Metabolome Database HMDB0003378
KEGG C00533
PharmGKB PA450635
SureChEMBL SCHEMBL7560
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