CIPROFLOXACIN HYDROCHLORIDE

Search structure
Synonyms:
Status: Approved (1987)
Entry Type: Small molecule
Molecule Category: Parent
UNII: 4BA73M5E37

Structure
InChI Key DIOIOSKKIYDRIQ-UHFFFAOYSA-N
Smile Cl.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
InChI
InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H

Physicochemical Descriptors

Property Name Value
Molecular Formula C17H19ClFN3O3
Molecular Weight 367.81
AlogP 1.58
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 3.0
Polar Surface Area 74.57
Molecular species ZWITTERION
Aromatic Rings 2.0
Heavy Atoms 24.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Bacterial DNA gyrase inhibitor
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Isomerase
- 0.2 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Rectal Neoplasms 2 D012004 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 310388
ChEMBL CHEMBL1202
EPA CompTox DTXSID1047788
FDA SRS 4BA73M5E37
PubChem 62999
SureChEMBL SCHEMBL42310
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