LISINOPRIL

Search structure
Synonyms:
Status: Approved (1987)
Entry Type: Small molecule
Molecule Category: Parent
ATC: C09AA03
UNII: E7199S1YWR

Structure
InChI Key RLAWWYSOJDYHDC-BZSNNMDCSA-N
Smile NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)N1CCC[C@H]1C(=O)O
InChI
InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C21H35N3O7
Molecular Weight 441.53
AlogP 1.24
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 4.0
Number of Rotational Bond 12.0
Polar Surface Area 132.96
Molecular species ZWITTERION
Aromatic Rings 1.0
Heavy Atoms 29.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Angiotensin-converting enzyme inhibitor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Heart Failure 4 D006333 FDA

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 6503
ChEMBL CHEMBL419213
DrugBank DB00722
EPA CompTox DTXSID2045600
FDA SRS E7199S1YWR
Human Metabolome Database HMDB01938
PDB LPR
PubChem 5362118
SureChEMBL SCHEMBL15680
ChEBI 6503
ChEMBL CHEMBL1237
DrugBank DB00722
DrugCentral 1587
EPA CompTox DTXSID6040537
FDA SRS E7199S1YWR
Human Metabolome Database HMDB01938
Guide to Pharmacology 6360
PDB LPR
PharmGKB PA450242
PubChem 5362118
SureChEMBL SCHEMBL15680
ZINC ZINC000003812863
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