| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Small molecule |
| Molecule Category: | UKNOWN |
| UNII: | 578H0RMP25 |
Structure
| InChI Key | TUOSYWCFRFNJBS-BHVANESWSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C40H33F3N4O3 |
| Molecular Weight | 674.72 |
| AlogP | 8.25 |
| Hydrogen Bond Acceptor | 4.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 83.44 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 6.0 |
| Heavy Atoms | 50.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Other cytosolic protein
|
- | 0-3 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Obesity | 1 | D009765 | ClinicalTrials |
Related Entries
Scaffolds
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL410414 |
| DrugBank | DB11399 |
| EPA CompTox | DTXSID00897432 |
| FDA SRS | 578H0RMP25 |
| SureChEMBL | SCHEMBL37781 |
| ZINC | ZINC000003988502 |
CONTENTS