PRAZIQUANTEL

Search structure
Synonyms:
Status: Approved (1982)
Entry Type: Small molecule
Molecule Category: Parent
ATC: P02BA01
UNII: 6490C9U457

Structure
InChI Key FSVJFNAIGNNGKK-UHFFFAOYSA-N
Smile O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3C2C1
InChI
InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2

Physicochemical Descriptors

Property Name Value
Molecular Formula C19H24N2O2
Molecular Weight 312.41
AlogP 2.53
Hydrogen Bond Acceptor 2.0
Hydrogen Bond Donor 0.0
Number of Rotational Bond 1.0
Polar Surface Area 40.62
Molecular species NEUTRAL
Aromatic Rings 1.0
Heavy Atoms 23.0

Pharmacology

Action Mechanism of Action Reference
BLOCKER Voltage-activated calcium channel beta 1 subunit blocker PubMed PubMed Wikipedia
Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Transporter Electrochemical transporter SLC superfamily of solute carriers SLC21/SLCO family of organic anion transporting polypeptides
- - - - 126
Transporter Primary active transporter ATP-binding cassette ABCB subfamily
- 60270-96800 - - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Schistosomiasis haematobia 3 D012553 ClinicalTrials
Cysticercosis 3 D003551 ClinicalTrials
Schistosomiasis mansoni 2 D012555 ClinicalTrials

Related Entries

Scaffolds

Cross References

Resources Reference
ChEBI 91583
ChEMBL CHEMBL976
DrugBank DB01058
DrugCentral 2241
EPA CompTox DTXSID9021182
FDA SRS 6490C9U457
Human Metabolome Database HMDB0015191
KEGG C07367
PharmGKB PA164764583
SureChEMBL SCHEMBL16019896
CONTENTS