AFIMETORAN

Search structure
Synonyms:
Status: Phase 2
Entry Type: Small molecule
Molecule Category: UNKNOWN

Structure
InChI Key SNFVHLQYHFQOEP-UHFFFAOYSA-N
Smile Cc1c(-c2[nH]c3ccc(C4CCN(CC(N)=O)CC4)cc3c2C(C)C)cn2ncnc2c1C
InChI
InChI=1S/C26H32N6O/c1-15(2)24-20-11-19(18-7-9-31(10-8-18)13-23(27)33)5-6-22(20)30-25(24)21-12-32-26(28-14-29-32)17(4)16(21)3/h5-6,11-12,14-15,18,30H,7-10,13H2,1-4H3,(H2,27,33)

Physicochemical Descriptors

Property Name Value
Molecular Formula C26H32N6O
Molecular Weight 444.58
AlogP 4.28
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 2.0
Number of Rotational Bond 5.0
Polar Surface Area 92.31
Molecular species NEUTRAL
Aromatic Rings 4.0
Heavy Atoms 33.0

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Lupus Erythematosus, Systemic 2 D008180 ClinicalTrials
Lupus Erythematosus, Cutaneous 1 D008178 ClinicalTrials

Cross References

Resources Reference
ChEMBL CHEMBL4650329
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