| Synonyms: | |
| Status: | Phase 1 |
| Entry Type: | Unknown |
| Molecule Category: | UNKNOWN |
| UNII: | H6NYM0V650 |
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C41H43ClFN9O6 |
| Molecular Weight | 812.3 |
| AlogP | 3.7 |
| Hydrogen Bond Acceptor | 12.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 9.0 |
| Polar Surface Area | 181.17 |
| Molecular species | None |
| Aromatic Rings | 3.0 |
| Heavy Atoms | 58.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transcription factor
Nuclear receptor
Nuclear hormone receptor subfamily 3
Nuclear hormone receptor subfamily 3 group C
Nuclear hormone receptor subfamily 3 group C member 4
|
3.6-5.5 | - | - | - | 57 | |
|
Unclassified protein
|
- | - | - | - | 57 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Prostatic Neoplasms, Castration-Resistant | 1 | D064129 | ClinicalTrials |
| Prostatic Neoplasms | 1 | D011471 | ClinicalTrials |
Cross References
| Resources | Reference |
|---|---|
| ChEMBL | CHEMBL4802189 |
| FDA SRS | H6NYM0V650 |
CONTENTS