Synonyms:
Status: Approved (2022)
Entry Type: Unknown
Molecule Category: UNKNOWN

Physicochemical Descriptors

Property Name Value
Molecular Formula C34H40N4O10
Molecular Weight 664.71
AlogP 4.47
Hydrogen Bond Acceptor 7.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 4.0
Polar Surface Area 67.68
Molecular species None
Aromatic Rings 2.0
Heavy Atoms 35.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR Activin receptor type-1 inhibitor

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Polycythemia Vera 4 D011087 FDA
Primary Myelofibrosis 4 D055728 FDA