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ENT (5)
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NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
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PHARMACOLOGY (8)
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RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
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Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
JNJ-39393406
2
Small molecule
Investigational
Unknown
Unknown
Schizophrenia; Depressive Disorder; Smoking Cessation
Neuronal acetylcholine receptor protein alpha-7 subunit positive allosteric modulator
JNJ-39393406
×
Maximum Phase:
2
First Approval:
None
UNII:
T930SOU82P
Molecule Type:
Small molecule
Molecular Formula:
C19H18F2N6O3
Molecular Weight:
416.39
AlogP:
2.88
PSA:
94.4
HBD:
1.0
HBA:
#RotB:
6.0
Source:
PF-04217329
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PF-04217329
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ATOPAXAR HYDROBROMIDE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ATOPAXAR HYDROBROMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
K3D2WJ7U0I
Molecule Type:
Small molecule
Molecular Formula:
C29H39BrFN3O5
Molecular Weight:
608.55
AlogP:
4.79
PSA:
84.32
HBD:
1.0
HBA:
#RotB:
9.0
Source:
SELTOREXANT
2
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Liver Diseases; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Depressive Disorder, Major
Orexin receptor 2 antagonist
SELTOREXANT
×
Maximum Phase:
2
First Approval:
None
UNII:
AIS8N3O50B
Molecule Type:
Small molecule
Molecular Formula:
C21H22FN7O
Molecular Weight:
407.45
AlogP:
2.02
PSA:
80.04
HBD:
0.0
HBA:
#RotB:
3.0
Source:
GW813893
2
Small molecule
Investigational
Unknown
Unknown
Venous Thromboembolism
Unknown
GW813893
×
Maximum Phase:
2
First Approval:
None
UNII:
1Y3JD5PEMS
Molecule Type:
Small molecule
Molecular Formula:
C17H22ClN3O5S2
Molecular Weight:
447.97
AlogP:
1.14
PSA:
96.02
HBD:
1.0
HBA:
#RotB:
6.0
Source:
FX-005
2
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis, Knee
MAP kinase p38 alpha inhibitor
FX-005
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MIVAVOTINIB
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MIVAVOTINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
8QR88H79VX
Molecule Type:
Small molecule
Molecular Formula:
C17H21FN6O
Molecular Weight:
344.39
AlogP:
1.55
PSA:
97.86
HBD:
3.0
HBA:
#RotB:
3.0
Source:
FLORBENAZINE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FLORBENAZINE
×
Maximum Phase:
2
First Approval:
None
UNII:
K5GDY88W5X
Molecule Type:
Small molecule
Molecular Formula:
C21H32FNO3
Molecular Weight:
365.49
AlogP:
3.76
PSA:
41.93
HBD:
1.0
HBA:
#RotB:
7.0
Source:
ARTEFENOMEL
2
Small molecule
Investigational
Unknown
Unknown
Malaria; Malaria, Falciparum; Malaria, Vivax; Schistosomiasis haematobia
Unknown
ARTEFENOMEL
×
Maximum Phase:
2
First Approval:
None
UNII:
RIK029813G
Molecule Type:
Small molecule
Molecular Formula:
C28H39NO5
Molecular Weight:
469.62
AlogP:
4.88
PSA:
49.39
HBD:
0.0
HBA:
#RotB:
5.0
Source:
QUARFLOXIN
2
Small molecule
Investigational
Unknown
Unknown
Lymphoma; Carcinoid Tumor; Leukemia, Lymphocytic, Chronic, B-Cell
Unknown
QUARFLOXIN
×
Maximum Phase:
2
First Approval:
None
UNII:
8M31J5031Q
Molecule Type:
Small molecule
Molecular Formula:
C35H33FN6O3
Molecular Weight:
604.69
AlogP:
5.39
PSA:
92.59
HBD:
1.0
HBA:
#RotB:
6.0
Source:
PIRITREXIM
2
Small molecule
Investigational
Unknown
Unknown
Urethral Neoplasms; Urinary Bladder Neoplasms
Dihydrofolate reductase inhibitor
PIRITREXIM
×
Maximum Phase:
2
First Approval:
None
UNII:
MK2A783ZUT
Molecule Type:
Small molecule
Molecular Formula:
C17H19N5O2
Molecular Weight:
325.37
AlogP:
2.11
PSA:
109.17
HBD:
2.0
HBA:
#RotB:
4.0
Source:
ADC3680
2
Small molecule
Investigational
Unknown
Unknown
Asthma
G protein-coupled receptor 44 antagonist
ADC3680
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SPEBRUTINIB BESYLATE
2
Small molecule
Investigational
Unknown
Unknown
Leukemia; Lymphoma, Large B-Cell, Diffuse; Arthritis, Rheumatoid
Tyrosine-protein kinase BTK inhibitor
SPEBRUTINIB BESYLATE
×
Maximum Phase:
2
First Approval:
None
UNII:
RC3ET192UJ
Molecule Type:
Small molecule
Molecular Formula:
C28H28FN5O6S
Molecular Weight:
581.63
AlogP:
4.25
PSA:
97.4
HBD:
3.0
HBA:
#RotB:
10.0
Source:
TEGOBUVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
TEGOBUVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
5NOK5X389M
Molecule Type:
Small molecule
Molecular Formula:
C25H14F7N5
Molecular Weight:
517.41
AlogP:
6.73
PSA:
56.49
HBD:
0.0
HBA:
#RotB:
4.0
Source:
ETAVOPIVAT
2
Small molecule
Investigational
Unknown
Unknown
Anemia, Sickle Cell
Unknown
ETAVOPIVAT
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C22H23N3O6S
Molecular Weight:
457.51
AlogP:
0.77
PSA:
109.27
HBD:
1.0
HBA:
#RotB:
5.0
Source:
GOLVATINIB
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Squamous Cell; Neoplasms; Stomach Neoplasms
Hepatocyte growth factor receptor inhibitor
GOLVATINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
516Z3YP58E
Molecule Type:
Small molecule
Molecular Formula:
C33H37F2N7O4
Molecular Weight:
633.7
AlogP:
4.75
PSA:
119.14
HBD:
3.0
HBA:
#RotB:
8.0
Source:
CHF6001
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CHF6001
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
APR-246
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
APR-246
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EGANELISIB
2
Small molecule
Investigational
Unknown
Unknown
Unknown
PI3-kinase p110-gamma subunit inhibitor
EGANELISIB
×
Maximum Phase:
2
First Approval:
None
UNII:
FOF5155FMZ
Molecule Type:
Small molecule
Molecular Formula:
C30H24N8O2
Molecular Weight:
528.58
AlogP:
3.24
PSA:
125.13
HBD:
2.0
HBA:
#RotB:
4.0
Source:
DIHOMO-GAMMA-LINOLENIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Dermatitis, Atopic
Unknown
DIHOMO-GAMMA-LINOLENIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
FC398RK06S
Molecule Type:
Small molecule
Molecular Formula:
C20H34O2
Molecular Weight:
306.49
AlogP:
6.44
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
15.0
Source:
EPELSIBAN BESYLATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
EPELSIBAN BESYLATE
×
Maximum Phase:
2
First Approval:
None
UNII:
H629P9T4UN
Molecule Type:
Small molecule
Molecular Formula:
C36H44N4O7S
Molecular Weight:
676.84
AlogP:
2.76
PSA:
91.84
HBD:
1.0
HBA:
#RotB:
6.0
Source:
AZD1446
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease; Attention Deficit Disorder with Hyperactivity
Neuronal acetylcholine receptor; alpha4/beta2 agonist
AZD1446
×
Maximum Phase:
2
First Approval:
None
UNII:
ANR9OP1V17
Molecule Type:
Small molecule
Molecular Formula:
C11H13ClN2O2
Molecular Weight:
240.69
AlogP:
1.22
PSA:
45.48
HBD:
1.0
HBA:
#RotB:
1.0
Source:
JBPOS-0101
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
JBPOS-0101
×
Maximum Phase:
2
First Approval:
None
UNII:
D7NM51C3GU
Molecule Type:
Small molecule
Molecular Formula:
C10H12ClNO3
Molecular Weight:
229.66
AlogP:
1.86
PSA:
72.55
HBD:
2.0
HBA:
#RotB:
3.0
Source:
PROFLAVINE
2
Small molecule
Investigational
Unknown
Unknown
Genital Neoplasms, Female; Barrett Esophagus; Carcinoma, Squamous Cell; Uterine Neoplasms
DNA disrupting agent
PROFLAVINE
×
Maximum Phase:
2
First Approval:
None
UNII:
CY3RNB3K4T
Molecule Type:
Small molecule
Molecular Formula:
C13H11N3
Molecular Weight:
209.25
AlogP:
2.55
PSA:
64.93
HBD:
2.0
HBA:
#RotB:
0.0
Source:
HYDROXYPROGESTERONE
2
Small molecule
Investigational
Unknown
Unknown
Premature Birth
Unknown
HYDROXYPROGESTERONE
×
Maximum Phase:
2
First Approval:
None
UNII:
21807M87J2
Molecule Type:
Small molecule
Molecular Formula:
C21H30O3
Molecular Weight:
330.47
AlogP:
3.84
PSA:
54.37
HBD:
1.0
HBA:
#RotB:
1.0
Source:
GSK-3117391
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
Unknown
GSK-3117391
×
Maximum Phase:
2
First Approval:
None
UNII:
CKA3P0O1VI
Molecule Type:
Small molecule
Molecular Formula:
C22H33N3O4
Molecular Weight:
403.52
AlogP:
3.04
PSA:
100.55
HBD:
3.0
HBA:
#RotB:
9.0
Source:
MARALIXIBAT CHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Cholangitis, Sclerosing; Liver Cirrhosis, Biliary; Alagille Syndrome; Pruritus
Ileal bile acid transporter inhibitor
MARALIXIBAT CHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
V78M04F0XC
Molecule Type:
Small molecule
Molecular Formula:
C40H56ClN3O4S
Molecular Weight:
710.42
AlogP:
6.62
PSA:
70.08
HBD:
1.0
HBA:
#RotB:
13.0
Source:
BLZ945
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Amyotrophic Lateral Sclerosis
Unknown
BLZ945
×
Maximum Phase:
2
First Approval:
None
UNII:
7W3V82OQ0P
Molecule Type:
Small molecule
Molecular Formula:
C20H22N4O3S
Molecular Weight:
398.49
AlogP:
3.56
PSA:
96.37
HBD:
3.0
HBA:
#RotB:
5.0
Source:
HP184
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HP184
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
REVAPRAZAN
2
Small molecule
Investigational
Unknown
Unknown
Gastroesophageal Reflux
Unknown
REVAPRAZAN
×
Maximum Phase:
2
First Approval:
None
UNII:
5P184180P5
Molecule Type:
Small molecule
Molecular Formula:
C22H23FN4
Molecular Weight:
362.45
AlogP:
5.1
PSA:
41.05
HBD:
1.0
HBA:
#RotB:
3.0
Source:
VB-201
2
Small molecule
Investigational
Unknown
Unknown
Colitis, Ulcerative; Psoriasis; Severe Acute Respiratory Syndrome
Monocyte differentiation antigen CD14 inhibitor
VB-201
×
Maximum Phase:
2
First Approval:
None
UNII:
SJ5A8151JO
Molecule Type:
Small molecule
Molecular Formula:
C29H60NO8P
Molecular Weight:
581.77
AlogP:
6.33
PSA:
114.35
HBD:
1.0
HBA:
#RotB:
30.0
Source:
CTS-1027
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Unknown
CTS-1027
×
Maximum Phase:
2
First Approval:
None
UNII:
2QD3F58224
Molecule Type:
Small molecule
Molecular Formula:
C19H20ClNO6S
Molecular Weight:
425.89
AlogP:
3.21
PSA:
101.93
HBD:
2.0
HBA:
#RotB:
6.0
Source:
TAK-448
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms; Hypogonadism
Unknown
TAK-448
×
Maximum Phase:
2
First Approval:
None
UNII:
YO029HR229
Molecule Type:
Small molecule
Molecular Formula:
C58H80N16O14
Molecular Weight:
1225.38
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
PRS-211375
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Cannabinoid CB2 receptor agonist
PRS-211375
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
9-AMINOCAMPTOTHECIN
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Esophageal Neoplasms; Kidney Neoplasms; Lung Neoplasms; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Stomach Neoplasms
Unknown
9-AMINOCAMPTOTHECIN
×
Maximum Phase:
2
First Approval:
None
UNII:
5MB77ICE2Q
Molecule Type:
Small molecule
Molecular Formula:
C20H17N3O4
Molecular Weight:
363.37
AlogP:
1.66
PSA:
107.44
HBD:
2.0
HBA:
#RotB:
1.0
Source:
1
2
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Molecular Formula
Molecular Weight
ALogP
PSA