DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved DERMATOLOGY; OTHER INTRAVENOUS Neurofibromatosis 1; Hemorrhoids; Macular Degeneration; Melanoma; Tendinopathy; Tennis Elbow; Venous Insufficiency; Telangiectasis; Varicose Veins Unknown


Small molecule Approved OTHER OPHTHALMIC Conjunctivitis, Allergic; Eye Manifestations Histamine H1 receptor antagonist


Small molecule Approved PREGNANCY AND GYNECOLOGY ORAL Adenomyosis; Breast Neoplasms; Charcot-Marie-Tooth Disease; Depressive Disorder; Menopause; Premenstrual Syndrome; Hemorrhage; Contraception, Postcoital; Leiomyoma Progesterone receptor modulator


Small molecule Approved Unknown ORAL Carcinoma, Non-Small-Cell Lung; Hematologic Diseases; Non-alcoholic Fatty Liver Disease; Prostatic Neoplasms; Renal Insufficiency; Renal Insufficiency, Chronic; Coronary Disease; Atrial Fibrillation; Stroke; Thromboembolism; Venous Thromboembolism; Venous Thrombosis; Thrombosis Unknown


Small molecule Approved UROLOGY AND KIDNEY ORAL Metabolism, Inborn Errors; Amino Acid Metabolism, Inborn Errors; Hyperammonemia; Propionic Acidemia Carbamoyl-phosphate synthase [ammonia], mitochondrial positive allosteric modulator


Small molecule Approved Unknown Unknown Fallopian Tube Neoplasms; Melanoma; Ovarian Neoplasms; Hemangioendothelioma, Epithelioid; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Inflammatory Breast Neoplasms; Solitary Fibrous Tumors; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Sarcoma; Triple Negative Breast Neoplasms; Neoplasms Unknown


Small molecule Approved MUSCULOSKELETAL ORAL Cerebral Palsy; Motor Neuron Disease; Optic Neuritis; Renal Insufficiency; Carpal Tunnel Syndrome; Guillain-Barre Syndrome; Memory, Short-Term; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Wounds and Injuries; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis Voltage-gated potassium channel blocker

Small molecule

Approved

MUSCULOSKELETAL

ORAL

Cerebral Palsy; Motor Neuron Disease; Optic Neuritis; Renal Insufficiency; Carpal Tunnel Syndrome; Guillain-Barre Syndrome; Memory, Short-Term; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Wounds and Injuries; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis

Voltage-gated potassium channel blocker


Small molecule Approved Unknown Unknown Anorexia Nervosa; Leiomyoma; Dysmenorrhea; Endometriosis; Metrorrhagia; Menorrhagia Unknown


Small molecule Approved MUSCULOSKELETAL ORAL Astrocytoma; Breast Neoplasms; Cerebral Hemorrhage; Glioblastoma; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Unknown

Small molecule

Approved

MUSCULOSKELETAL

ORAL

Astrocytoma; Breast Neoplasms; Cerebral Hemorrhage; Glioblastoma; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Unknown


Small molecule Approved OTHER; RESPIRATORY INTRAVENOUS Kidney Diseases; Systemic Inflammatory Response Syndrome; Sepsis; Urinary Tract Infections; Infections; Pneumonia, Bacterial; Bacterial Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved Unknown Unknown Autistic Disorder; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Psychotic Disorders; Schizophrenia Unknown


Small molecule Approved Unknown Unknown Lichen Planus; Uterine Cervical Dysplasia Unknown


Small molecule Approved Unknown Unknown Attention Deficit Disorder with Hyperactivity Unknown


Small molecule Approved Unknown Unknown Amyotrophic Lateral Sclerosis; Blast Crisis; Carcinoma, Non-Small-Cell Lung; Cognitive Dysfunction; Dementia; Mesothelioma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Thymoma; Thymus Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Glioblastoma; Leukemia; Polycystic Kidney, Autosomal Dominant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms Tyrosine-protein kinase ABL inhibitor

Small molecule

Approved

Unknown

Amyotrophic Lateral Sclerosis; Blast Crisis; Carcinoma, Non-Small-Cell Lung; Cognitive Dysfunction; Dementia; Mesothelioma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Thymoma; Thymus Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Glioblastoma; Leukemia; Polycystic Kidney, Autosomal Dominant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms

Tyrosine-protein kinase ABL inhibitor


Small molecule Approved CANCER; DERMATOLOGY; OTHER TOPICAL Cheilitis; Molluscum Contagiosum; Warts; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Condylomata Acuminata; Keratosis; Keratosis, Seborrheic; Skin Diseases; Keratosis, Actinic Unknown


Small molecule Approved Unknown Unknown Pancreatitis; Arthroplasty, Replacement; Atrial Fibrillation; Embolism; Stroke; Venous Thromboembolism; Venous Thrombosis Thrombin inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved RESPIRATORY ORAL Glioblastoma; Heart Failure; Idiopathic Pulmonary Fibrosis; Hernias, Diaphragmatic, Congenital; Pulmonary Embolism; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary Endothelin receptor, ET-A/ET-B antagonist


Small molecule Approved Unknown Unknown Community-Acquired Infections; Kidney Failure, Chronic; Pneumonia; Pneumonia, Bacterial; Skin Diseases, Infectious Bacterial penicillin-binding protein inhibitor


Small molecule Approved Unknown Unknown Acne Vulgaris; Anemia, Iron-Deficiency Unknown


Small molecule Approved OTHER INJECTION; INTRAVENOUS; IV (INFUSION) Brain Neoplasms; Glioma; Adrenal Cortex Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Liposarcoma; Ovarian Neoplasms; Penile Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Testicular Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant Tubulin inhibitor

Small molecule

Approved

OTHER

INJECTION; INTRAVENOUS; IV (INFUSION)

Brain Neoplasms; Glioma; Adrenal Cortex Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Liposarcoma; Ovarian Neoplasms; Penile Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Testicular Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant

Tubulin inhibitor


Small molecule Approved IMMUNE SYSTEM ORAL Thrombocytopenia; Hepatitis C; Hepatitis C, Chronic; Virus Diseases Hepatitis C virus serine protease, NS3/NS4A inhibitor


Small molecule Approved OTHER; UROLOGY AND KIDNEY ORAL Kidney Diseases; Erectile Dysfunction Phosphodiesterase 5A inhibitor


Small molecule Approved CARDIOVASCULAR ORAL Cardiovascular Diseases; Ischemia; Kidney Diseases; Kidney Failure, Chronic; Aortic Aneurysm, Abdominal; Carotid Stenosis; Pulmonary Disease, Chronic Obstructive; Anemia, Sickle Cell; Angina, Stable; Aortic Valve Stenosis; Atrial Fibrillation; Influenza, Human; Intracranial Aneurysm; Ischemic Stroke; Non-ST Elevated Myocardial Infarction; Peripheral Arterial Disease; Pneumonia; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Acute Coronary Syndrome; Coronary Artery Disease; Diabetes Mellitus, Type 2; Myocardial Infarction; Peripheral Vascular Diseases; Stroke; Thrombosis Purinergic receptor P2Y12 negative allosteric modulator

Small molecule

Approved

CARDIOVASCULAR

ORAL

Cardiovascular Diseases; Ischemia; Kidney Diseases; Kidney Failure, Chronic; Aortic Aneurysm, Abdominal; Carotid Stenosis; Pulmonary Disease, Chronic Obstructive; Anemia, Sickle Cell; Angina, Stable; Aortic Valve Stenosis; Atrial Fibrillation; Influenza, Human; Intracranial Aneurysm; Ischemic Stroke; Non-ST Elevated Myocardial Infarction; Peripheral Arterial Disease; Pneumonia; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Acute Coronary Syndrome; Coronary Artery Disease; Diabetes Mellitus, Type 2; Myocardial Infarction; Peripheral Vascular Diseases; Stroke; Thrombosis

Purinergic receptor P2Y12 negative allosteric modulator


Small molecule Approved DERMATOLOGY ORAL Lymphoma; Paraganglioma; Skin Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Craniopharyngioma; Hematologic Neoplasms; Histiocytosis; Histiocytosis, Langerhans-Cell; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Pancreatic Neoplasms; Thyroid Neoplasms; Melanoma; Neoplasms Serine/threonine-protein kinase B-raf inhibitor

Small molecule

Approved

DERMATOLOGY

ORAL

Lymphoma; Paraganglioma; Skin Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Craniopharyngioma; Hematologic Neoplasms; Histiocytosis; Histiocytosis, Langerhans-Cell; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Pancreatic Neoplasms; Thyroid Neoplasms; Melanoma; Neoplasms

Serine/threonine-protein kinase B-raf inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Amyotrophic Lateral Sclerosis; Depressive Disorder; Depressive Disorder, Major; Neuralgia, Postherpetic; Epilepsy; Seizures KCNQ (Kv7) potassium channel opener

Small molecule

Approved

RESPIRATORY

ORAL

Multiple Sclerosis; Acute Lung Injury; Alveolitis, Extrinsic Allergic; Bronchiolitis Obliterans; Burns; Carcinoma, Squamous Cell; Cardiomyopathy, Hypertrophic; Glomerulosclerosis, Focal Segmental; Heart Failure; Leiomyoma; Lung Diseases, Interstitial; Lung Neoplasms; Nephrotic Syndrome; Neurofibromatosis 1; Pancreatitis; Proteinuria; Pulmonary Fibrosis; Radiation Pneumonitis; Renal Insufficiency; Renal Insufficiency, Chronic; Scleroderma, Systemic; Diabetic Foot; Keloid; Pneumoconiosis; Pneumonia; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Immune System Diseases; Lung Diseases; Respiratory Tract Diseases

Unknown

Small molecule

Approved

Unknown

Carcinoma, Pancreatic Ductal; Dermatitis; Glioblastoma; Leukemia, Biphenotypic, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Malignant Atrophic Papulosis; Neuromyelitis Optica; Paraganglioma; Pneumonia; Uveal Melanoma; Alopecia Areata; Anemia; Arthritis, Rheumatoid; beta-Thalassemia; Breast Neoplasms; Bronchiolitis Obliterans; Bronchiolitis Obliterans Syndrome; Cachexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Dermatitis, Seborrheic; Hematologic Neoplasms; Hidradenitis Suppurativa; Histiocytosis; HIV Infections; Hodgkin Disease; Hypereosinophilic Syndrome; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lichen Planus; Lichen Sclerosus et Atrophicus; Lupus Erythematosus, Discoid; Lymphoma; Multiple Myeloma; Necrobiosis Lipoidica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Immunodeficiency Diseases; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Dermatitis, Atopic; Graft vs Host Disease; Lymphohistiocytosis, Hemophagocytic; Macrophage Activation Syndrome; Myeloproliferative Disorders; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Prurigo; Severe Acute Respiratory Syndrome; Thrombocythemia, Essential; Vitiligo; Eczema; Neoplasms

Unknown


Small molecule Approved OTHER ORAL Hepatitis C; Insulin Resistance; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Small molecule

Approved

CARDIOVASCULAR; HEMATOLOGY; OTHER

ORAL

Blood Coagulation Disorders; Obesity, Morbid; Renal Insufficiency, Chronic; Anemia, Sickle Cell; Aortic Valve Disease; Heart Diseases; Hemorrhage; Ischemia; Multiple Myeloma; Thromboembolism; Angina, Unstable; Aortic Valve Stenosis; Diabetes Mellitus, Type 2; Hematoma; Hip Fractures; Ischemic Stroke; Liver Cirrhosis; Myocardial Infarction; Neoplasms; Polyendocrinopathies, Autoimmune; Renal Insufficiency; Rheumatic Heart Disease; Severe Acute Respiratory Syndrome; Thrombocytopenia; Acute Coronary Syndrome; Arthroplasty, Replacement; Atrial Fibrillation; Coronary Artery Disease; Peripheral Arterial Disease; Pulmonary Embolism; Stroke; Thrombosis; Venous Thromboembolism; Venous Thrombosis

Coagulation factor X inhibitor

Small molecule

Approved

CANCER; OTHER; RESPIRATORY

ORAL

Breast Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Prostatic Neoplasms, Castration-Resistant; Adenocarcinoma; Bile Duct Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Gallbladder Neoplasms; Granuloma, Plasma Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Multiple Myeloma; Neurofibromatosis 2; Stomach Neoplasms; Uveal Melanoma; Adenocarcinoma of Lung; Carcinoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms

ALK tyrosine kinase receptor inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Polycystic Ovary Syndrome; Renal Insufficiency; Breast Neoplasms; Diabetes Mellitus, Type 1; Obesity; Renal Insufficiency, Chronic; Diabetic Nephropathies; Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sodium/glucose cotransporter 2 inhibitor


Small molecule Approved Unknown Unknown Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms Androgen Receptor antagonist


Small molecule Approved Unknown Unknown Marijuana Abuse; Memory Disorders; Anxiety Disorders; Depressive Disorder Unknown


Small molecule Approved GASTROINTESTINAL ORAL Clostridium Infections; Diarrhea; Infections DNA-directed RNA polymerase inhibitor