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Total: 6532
Small molecule
Approved
Unknown
Unknown
Amyotrophic Lateral Sclerosis; Blast Crisis; Carcinoma, Non-Small-Cell Lung; Dementia; Leukemia, Myeloid, Acute; Mesothelioma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymoma; Thymus Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Glioblastoma; Leukemia; Polycystic Kidney, Autosomal Dominant; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms
Bcr/Abl fusion protein
Small molecule
Approved
Unknown
Unknown
Kidney Failure, Chronic; Pneumonia, Bacterial
Bacterial penicillin-binding protein inhibitor
Small molecule
Unknown
Unknown
Unknown
Pancreatitis; Atrial Fibrillation; Embolism; Stroke; Venous Thrombosis
Thrombin inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
INTRAVENOUS
Kidney Diseases; Meningitis; Pneumonia; Systemic Inflammatory Response Syndrome; Sepsis; Urinary Tract Infections; Infections; Pneumonia, Bacterial; Bacterial Infections
Unknown
Small molecule
Approved
MUSCULOSKELETAL
ORAL
Optic Neuritis; Cerebral Palsy; Motor Neuron Disease; Renal Insufficiency; Guillain-Barre Syndrome; Muscular Atrophy, Spinal; Prostatic Diseases; Sleep Apnea, Obstructive; Trauma, Nervous System; Ischemic Stroke; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Muscle Spasticity; Spinal Cord Injuries; Stroke; Multiple Sclerosis
Voltage-gated potassium channel blocker
Small molecule
Approved
Unknown
Unknown
Uterine Cervical Dysplasia; Cervical Intraepithelial Neoplasia; Lichen Planus
Unknown
Small molecule
Approved
Unknown
Unknown
Anorexia Nervosa; Dysmenorrhea; Endometriosis; Metrorrhagia; Menorrhagia
Unknown
Small molecule
Approved
Unknown
Unknown
Autistic Disorder; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Schizophrenia; Psychotic Disorders
Unknown
Small molecule
Approved
CANCER; DERMATOLOGY; OTHER
TOPICAL
Molluscum Contagiosum; Cheilitis; Warts; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Condylomata Acuminata; Keratosis; Keratosis, Seborrheic; Lentigo; Skin Diseases; Keratosis, Actinic
Unknown
Small molecule
Unknown
Unknown
Unknown
Acne Vulgaris; Anemia, Iron-Deficiency
Unknown
Small molecule
Approved
MUSCULOSKELETAL
ORAL
Astrocytoma; Glioblastoma; Breast Neoplasms; Renal Insufficiency; Rett Syndrome; Asthma; Optic Neuritis; Schizophrenia; Severe Acute Respiratory Syndrome; Stroke; Uveitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Immune System Diseases
Unknown
Small molecule
Approved
RESPIRATORY
ORAL
Glioblastoma; Heart Failure; Idiopathic Pulmonary Fibrosis; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Hypertension
Endothelin receptor, ET-A/ET-B antagonist
Small molecule
Approved
OTHER
OPHTHALMIC
Conjunctivitis, Allergic; Eye Manifestations
Histamine H1 receptor antagonist
Small molecule
Approved
PREGNANCY AND GYNECOLOGY
ORAL
Adenomyosis; Breast Neoplasms; Charcot-Marie-Tooth Disease; Depressive Disorder; Menopause; Premenstrual Syndrome; Hemorrhage; Leiomyoma
Progesterone receptor modulator
Small molecule
Approved
Unknown
ORAL
Hematologic Diseases; Non-alcoholic Fatty Liver Disease; Prostatic Neoplasms; Renal Insufficiency; Renal Insufficiency, Chronic; Coronary Disease; Atrial Fibrillation; Stroke; Thromboembolism; Venous Thromboembolism; Venous Thrombosis; Thrombosis
Unknown
Small molecule
Approved
Unknown
Unknown
Carcinoma, Renal Cell; Fallopian Tube Neoplasms; Melanoma; Ovarian Neoplasms; Hemangioendothelioma, Epithelioid; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Inflammatory Breast Neoplasms; Sarcoma; Solitary Fibrous Tumors; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms
Unknown
Small molecule
Unknown
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
INJECTION; INTRAVENOUS; IV (INFUSION)
Brain Neoplasms; Glioma; Adrenal Cortex Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Liposarcoma; Ovarian Neoplasms; Penile Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Testicular Neoplasms; Urinary Bladder Neoplasms; Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Tubulin inhibitor
Small molecule
Approved
DERMATOLOGY; OTHER
INTRAVENOUS
Hemorrhoids; Macular Degeneration; Melanoma; Tennis Elbow; Telangiectasis; Varicose Veins
Unknown
Small molecule
Approved
UROLOGY AND KIDNEY
ORAL
Metabolism, Inborn Errors; Propionic Acidemia; Hyperammonemia
Carbamoyl-phosphate synthase [ammonia], mitochondrial positive allosteric modulator
Small molecule
Approved
CARDIOVASCULAR
ORAL
Cardiovascular Diseases; Ischemia; Kidney Diseases; Aortic Aneurysm, Abdominal; Carotid Stenosis; Pneumonia; Pulmonary Disease, Chronic Obstructive; Anemia, Sickle Cell; Angina, Stable; Aortic Valve Stenosis; Atrial Fibrillation; Intracranial Aneurysm; Non-ST Elevated Myocardial Infarction; Peripheral Arterial Disease; Renal Insufficiency, Chronic; ST Elevation Myocardial Infarction; Acute Coronary Syndrome; Coronary Artery Disease; Coronary Disease; Diabetes Mellitus, Type 2; Myocardial Infarction; Stroke; Thrombosis
Purinergic receptor P2Y12 negative allosteric modulator
Small molecule
Approved
OTHER
TOPICAL
Lice Infestations
Nicotinic acetylcholine receptor agonist
Small molecule
Approved
DERMATOLOGY
ORAL
Glioma; Lymphoma; Skin Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Craniopharyngioma; Histiocytosis; Histiocytosis, Langerhans-Cell; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Thyroid Neoplasms; Melanoma; Neoplasms
Serine/threonine-protein kinase B-raf inhibitor
Small molecule
Approved
Unknown
Unknown
Essential Hypertension; Hypertension; Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Kidney Diseases; Erectile Dysfunction
Phosphodiesterase 5A inhibitor
Small molecule
Approved
RESPIRATORY
ORAL
Multiple Sclerosis; Alveolitis, Extrinsic Allergic; Bronchiolitis Obliterans; Burns; Cardiomyopathy, Hypertrophic; Glomerulosclerosis, Focal Segmental; Heart Failure; Leiomyoma; Liver Cirrhosis; Lung Diseases, Interstitial; Nephrotic Syndrome; Neurofibromatosis 1; Pneumoconiosis; Proteinuria; Pulmonary Fibrosis; Radiation Pneumonitis; Renal Insufficiency; Renal Insufficiency, Chronic; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Diabetic Foot; Keloid; Pneumonia; Idiopathic Pulmonary Fibrosis; Immune System Diseases
Unknown
Small molecule
Approved
OTHER
INHALATION
Asthma; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
Small molecule
Approved
Unknown
Unknown
Glioblastoma; Leukemia, Biphenotypic, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Pneumonia; Alopecia Areata; Arthritis, Rheumatoid; beta-Thalassemia; Breast Neoplasms; Bronchiolitis Obliterans; Cachexia; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Hematologic Neoplasms; Hidradenitis Suppurativa; HIV Infections; Hodgkin Disease; Hypereosinophilic Syndrome; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lichen Planus; Lupus Erythematosus, Discoid; Lymphoma; Multiple Myeloma; Necrobiosis Lipoidica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Thrombocythemia, Essential; Dermatitis, Atopic; Graft vs Host Disease; Lymphohistiocytosis, Hemophagocytic; Myeloproliferative Disorders; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Severe Acute Respiratory Syndrome; Vitiligo; Neoplasms
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Amyotrophic Lateral Sclerosis; Depressive Disorder; Depressive Disorder, Major; Neuralgia, Postherpetic; Epilepsy; Seizures
KCNQ (Kv7) potassium channel opener
Small molecule
Approved
Unknown
Unknown
Parkinson Disease; Multiple System Atrophy; Parkinsonian Disorders
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms
Androgen Receptor antagonist
Small molecule
Approved
GASTROINTESTINAL
ORAL
Clostridium Infections; Diarrhea; Infections
DNA-directed RNA polymerase inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Polycystic Ovary Syndrome; Renal Insufficiency; Diabetes Mellitus, Type 1; Obesity; Diabetic Nephropathies; Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2
Sodium/glucose cotransporter 2 inhibitor