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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
GSK-461364
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin
Serine/threonine-protein kinase PLK1 inhibitor
GSK-461364
×
Maximum Phase:
1
First Approval:
None
UNII:
8QO27TK6Q4
Molecule Type:
Small molecule
Molecular Formula:
C27H28F3N5O2S
Molecular Weight:
543.62
AlogP:
5.09
PSA:
76.62
HBD:
1.0
HBA:
#RotB:
7.0
Source:
CXD-101
1
Small molecule
Investigational
Unknown
Unknown
Colorectal Neoplasms; Neoplasms
Unknown
CXD-101
×
Maximum Phase:
1
First Approval:
None
UNII:
5TNV87ICD2
Molecule Type:
Small molecule
Molecular Formula:
C24H29N5O
Molecular Weight:
403.53
AlogP:
3.94
PSA:
76.18
HBD:
2.0
HBA:
#RotB:
5.0
Source:
LISAVANBULIN
1
Small molecule
Investigational
Unknown
Unknown
Glioblastoma; Neoplasms
Unknown
LISAVANBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
5PT0QP06X5
Molecule Type:
Small molecule
Molecular Formula:
C26H29N9O3
Molecular Weight:
515.58
AlogP:
2.69
PSA:
190.77
HBD:
4.0
HBA:
#RotB:
13.0
Source:
131-I-MIP-1145
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
131-I-MIP-1145
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TOLONIUM CHLORIDE
1
Small molecule
Investigational
Unknown
Unknown
Dental Caries
Unknown
TOLONIUM CHLORIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
15XUH0X66N
Molecule Type:
Small molecule
Molecular Formula:
C15H16ClN3S
Molecular Weight:
305.83
AlogP:
3.69
PSA:
42.15
HBD:
1.0
HBA:
#RotB:
1.0
Source:
RG7893
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Sodium channel protein type IX alpha subunit blocker
RG7893
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INZOMELID
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
INZOMELID
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C19H24N4O3S
Molecular Weight:
388.49
AlogP:
2.95
PSA:
93.09
HBD:
2.0
HBA:
#RotB:
4.0
Source:
5-METHYL-2'-FLUOROARAURACIL F-18
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
5-METHYL-2'-FLUOROARAURACIL F-18
×
Maximum Phase:
1
First Approval:
None
UNII:
J932A2CDQO
Molecule Type:
Small molecule
Molecular Formula:
C10H13FN2O5
Molecular Weight:
259.22
AlogP:
-1.57
PSA:
104.55
HBD:
3.0
HBA:
#RotB:
2.0
Source:
RINTODESTRANT
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Ductal
Unknown
RINTODESTRANT
×
Maximum Phase:
1
First Approval:
None
UNII:
W3Y784Y0ES
Molecule Type:
Small molecule
Molecular Formula:
C26H19FO5S
Molecular Weight:
462.5
AlogP:
6.48
PSA:
83.83
HBD:
2.0
HBA:
#RotB:
6.0
Source:
METHANESULFONYL FLUORIDE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
METHANESULFONYL FLUORIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
9H250YYY0R
Molecule Type:
Small molecule
Molecular Formula:
CH3FO2S
Molecular Weight:
98.1
AlogP:
-0.08
PSA:
34.14
HBD:
0.0
HBA:
#RotB:
0.0
Source:
MBC-11
1
Small molecule
Investigational
Unknown
Unknown
Neoplasm Metastasis
Unknown
MBC-11
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C11H20N3O14P3
Molecular Weight:
511.21
AlogP:
-2.39
PSA:
281.42
HBD:
8.0
HBA:
#RotB:
8.0
Source:
ETHANE DIMETHANE SULFONATE
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Lung Neoplasms; Lymphoma, Non-Hodgkin
Unknown
ETHANE DIMETHANE SULFONATE
×
Maximum Phase:
1
First Approval:
None
UNII:
EW8V7BJ66Q
Molecule Type:
Small molecule
Molecular Formula:
C4H10O6S2
Molecular Weight:
218.25
AlogP:
-1.06
PSA:
86.74
HBD:
0.0
HBA:
#RotB:
5.0
Source:
USL311
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
USL311
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VLX-1005
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VLX-1005
×
Maximum Phase:
1
First Approval:
None
UNII:
JKU4XCC48Y
Molecule Type:
Small molecule
Molecular Formula:
C21H19N3O4S2
Molecular Weight:
441.53
AlogP:
4.42
PSA:
100.55
HBD:
3.0
HBA:
#RotB:
7.0
Source:
TEGLARINAD
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
TEGLARINAD
×
Maximum Phase:
1
First Approval:
None
UNII:
NUG9P5GWZB
Molecule Type:
Small molecule
Molecular Formula:
C30H43ClN5O8+
Molecular Weight:
637.15
AlogP:
3.91
PSA:
145.77
HBD:
2.0
HBA:
#RotB:
23.0
Source:
LINZAGOLIX
1
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Liver Diseases; Endometriosis
Gonadotropin-releasing hormone receptor antagonist
LINZAGOLIX
×
Maximum Phase:
1
First Approval:
None
UNII:
7CDW97HUEX
Molecule Type:
Small molecule
Molecular Formula:
C22H15F3N2O7S
Molecular Weight:
508.43
AlogP:
3.45
PSA:
119.85
HBD:
2.0
HBA:
#RotB:
7.0
Source:
RODATRISTAT ETHYL
1
Small molecule
Investigational
Unknown
Unknown
Hypertension, Pulmonary
Tryptophan 5-hydroxylase 1 inhibitor
RODATRISTAT ETHYL
×
Maximum Phase:
1
First Approval:
None
UNII:
507FY6OL37
Molecule Type:
Small molecule
Molecular Formula:
C29H31ClF3N5O3
Molecular Weight:
590.05
AlogP:
5.57
PSA:
102.6
HBD:
2.0
HBA:
#RotB:
7.0
Source:
ZOTATIFIN
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Severe Acute Respiratory Syndrome
Unknown
ZOTATIFIN
×
Maximum Phase:
1
First Approval:
None
UNII:
2EWN8Z05CN
Molecule Type:
Small molecule
Molecular Formula:
C28H29N3O5
Molecular Weight:
487.56
AlogP:
2.78
PSA:
108.07
HBD:
2.0
HBA:
#RotB:
6.0
Source:
FILOCICLOVIR
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FILOCICLOVIR
×
Maximum Phase:
1
First Approval:
None
UNII:
EAO0TD9B13
Molecule Type:
Small molecule
Molecular Formula:
C11H13N5O3
Molecular Weight:
263.26
AlogP:
-1.08
PSA:
130.05
HBD:
4.0
HBA:
#RotB:
3.0
Source:
OSI-930
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Stem cell growth factor receptor inhibitor
OSI-930
×
Maximum Phase:
1
First Approval:
None
UNII:
G1PEG5Q9Y2
Molecule Type:
Small molecule
Molecular Formula:
C22H16F3N3O2S
Molecular Weight:
443.45
AlogP:
6.06
PSA:
63.25
HBD:
2.0
HBA:
#RotB:
6.0
Source:
MOMELOTINIB DIHYDROCHLORIDE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MOMELOTINIB DIHYDROCHLORIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
RBH995N496
Molecule Type:
Small molecule
Molecular Formula:
C23H24Cl2N6O2
Molecular Weight:
487.39
AlogP:
2.98
PSA:
103.17
HBD:
2.0
HBA:
#RotB:
6.0
Source:
HYMECROMONE
1
Small molecule
Investigational
Unknown
Unknown
Respiratory Tract Diseases
Unknown
HYMECROMONE
×
Maximum Phase:
1
First Approval:
None
UNII:
3T5NG4Q468
Molecule Type:
Small molecule
Molecular Formula:
C10H8O3
Molecular Weight:
176.17
AlogP:
1.81
PSA:
50.44
HBD:
1.0
HBA:
#RotB:
0.0
Source:
TEPOTINIB HYDROCHLORIDE
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Carcinoma, Non-Small-Cell Lung
Hepatocyte growth factor receptor inhibitor
TEPOTINIB HYDROCHLORIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
VY5YX2TQ1F
Molecule Type:
Small molecule
Molecular Formula:
C29H31ClN6O3
Molecular Weight:
547.06
AlogP:
4.01
PSA:
96.93
HBD:
0.0
HBA:
#RotB:
7.0
Source:
BIAPENEM
1
Small molecule
Investigational
Unknown
Unknown
Bacterial Infections
Unknown
BIAPENEM
×
Maximum Phase:
1
First Approval:
None
UNII:
YR5U3L9ZH1
Molecule Type:
Small molecule
Molecular Formula:
C15H18N4O4S
Molecular Weight:
350.4
AlogP:
-1.89
PSA:
102.37
HBD:
1.0
HBA:
#RotB:
4.0
Source:
PF-05180999
1
Small molecule
Investigational
Unknown
Unknown
Migraine Disorders; Schizophrenia
Unknown
PF-05180999
×
Maximum Phase:
1
First Approval:
None
UNII:
5L84K4IEN9
Molecule Type:
Small molecule
Molecular Formula:
C19H17F3N8
Molecular Weight:
414.4
AlogP:
3.12
PSA:
77.03
HBD:
0.0
HBA:
#RotB:
3.0
Source:
GSK-2018682
1
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting
Unknown
GSK-2018682
×
Maximum Phase:
1
First Approval:
None
UNII:
NJL503AIJA
Molecule Type:
Small molecule
Molecular Formula:
C22H21ClN4O4
Molecular Weight:
440.89
AlogP:
5.06
PSA:
103.27
HBD:
1.0
HBA:
#RotB:
8.0
Source:
E-2212
1
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Unknown
E-2212
×
Maximum Phase:
1
First Approval:
None
UNII:
V9KGF25853
Molecule Type:
Small molecule
Molecular Formula:
C25H23F3N6O
Molecular Weight:
480.49
AlogP:
5.29
PSA:
70.65
HBD:
0.0
HBA:
#RotB:
5.0
Source:
8-CHLOROADENOSINE
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute
Unknown
8-CHLOROADENOSINE
×
Maximum Phase:
1
First Approval:
None
UNII:
PA05MFH3I7
Molecule Type:
Small molecule
Molecular Formula:
C10H12ClN5O4
Molecular Weight:
301.69
AlogP:
-1.33
PSA:
139.54
HBD:
4.0
HBA:
#RotB:
2.0
Source:
AS-703988
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
AS-703988
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIIF 1149 BS
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BIIF 1149 BS
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IRSOGLADINE MALEATE
1
Small molecule
Investigational
Unknown
Unknown
Gastritis; Peptic Ulcer; Stomach Ulcer
Unknown
IRSOGLADINE MALEATE
×
Maximum Phase:
1
First Approval:
None
UNII:
66GVU60EPQ
Molecule Type:
Small molecule
Molecular Formula:
C13H11Cl2N5O4
Molecular Weight:
372.17
AlogP:
2.01
PSA:
90.71
HBD:
2.0
HBA:
#RotB:
1.0
Source:
VS-4718
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Pancreatic Neoplasms
Focal adhesion kinase 1 inhibitor
VS-4718
×
Maximum Phase:
1
First Approval:
None
UNII:
L2BD0MW4OL
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FEDOVAPAGON
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FEDOVAPAGON
×
Maximum Phase:
1
First Approval:
None
UNII:
VX2GBO4I0V
Molecule Type:
Small molecule
Molecular Formula:
C27H34N4O3
Molecular Weight:
462.59
AlogP:
3.74
PSA:
72.96
HBD:
1.0
HBA:
#RotB:
4.0
Source:
LGX-806
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Serine/threonine-protein kinase B-raf inhibitor
LGX-806
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-3043
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AZD-3043
×
Maximum Phase:
1
First Approval:
None
UNII:
372AB76LQL
Molecule Type:
Small molecule
Molecular Formula:
C19H29NO5
Molecular Weight:
351.44
AlogP:
2.83
PSA:
65.07
HBD:
0.0
HBA:
#RotB:
11.0
Source:
1
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Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA