| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1967) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt Prodrug |
| UNII: | 9IFA5XM7R2 |
| Parent Compound: | BETAMETHASONE |
Structure
| InChI Key | SNHRLVCMMWUAJD-SUYDQAKGSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C27H37FO6 |
| Molecular Weight | 476.59 |
| AlogP | 3.64 |
| Hydrogen Bond Acceptor | 6.0 |
| Hydrogen Bond Donor | 2.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 100.9 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 34.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Oxidoreductase
|
- | - | - | - | 67 | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 10 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Dermatitis, Atopic | 3 | D003876 | ClinicalTrials |
| Oral Submucous Fibrosis | 3 | D009914 | ClinicalTrials |
| Psoriasis | 1 | D011565 | ClinicalTrials |
| Psoriasis | 1 | D011565 | ClinicalTrials |
Related Entries
Scaffolds
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 31277 |
| ChEMBL | CHEMBL1497 |
| DrugCentral | 354 |
| EPA CompTox | DTXSID7022673 |
| FDA SRS | 9IFA5XM7R2 |
| PubChem | 16533 |
| SureChEMBL | SCHEMBL7270 |
| ZINC | ZINC000003882052 |
CONTENTS