| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1950) Withdrawn (2012) |
| Entry Type: | Small molecule |
| Molecule Category: | Parent |
| ATC: | D06AX02 |
| UNII: | 66974FR9Q1 |
Structure
| InChI Key | WIIZWVCIJKGZOK-RKDXNWHRSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C11H12Cl2N2O5 |
| Molecular Weight | 323.13 |
| AlogP | 0.91 |
| Hydrogen Bond Acceptor | 5.0 |
| Hydrogen Bond Donor | 3.0 |
| Number of Rotational Bond | 6.0 |
| Polar Surface Area | 112.7 |
| Molecular species | NEUTRAL |
| Aromatic Rings | 1.0 |
| Heavy Atoms | 20.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Enzyme
Ligase
|
7900 | - | - | - | - | |
|
Other cytosolic protein
|
- | 430 | - | - | - | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 85 | |
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC22 family of organic cation and anion transporters
|
- | - | - | - | 1 | |
|
Unclassified protein
|
- | 430 | - | - | - |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Osteomyelitis | 0 | D010019 | ClinicalTrials |
Related Entries
Adverse Reactions
System Organ Classification (SOC)
Cross References
| Resources | Reference |
|---|---|
| CAS NUMBER | 56-75-7 |
| ChEBI | 17698 |
| ChEMBL | CHEMBL130 |
| DrugBank | DB00446 |
| DrugCentral | 589 |
| EPA CompTox | DTXSID7020265 |
| FDA SRS | 66974FR9Q1 |
| Human Metabolome Database | HMDB0014589 |
| Guide to Pharmacology | 10901 |
| KEGG | C00918 |
| PDB | CLM |
| PubChem | 5959 |
| SureChEMBL | SCHEMBL16111 |
| ZINC | ZINC000000113382 |
CONTENTS