FLUOROMETHOLONE ACETATE

Search structure
Trade Names:
Synonyms:
Status: Approved (1986)
Entry Type: Small molecule
Molecule Category: Salt Prodrug
UNII: 9I50C3I3OK
Parent Compound: FLUOROMETHOLONE

Structure
InChI Key YRFXGQHBPBMFHW-SBTZIJSASA-N
Smile CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
InChI
InChI=1S/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C24H31FO5
Molecular Weight 418.51
AlogP 3.49
Hydrogen Bond Acceptor 5.0
Hydrogen Bond Donor 1.0
Number of Rotational Bond 2.0
Polar Surface Area 80.67
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 30.0

Pharmacology

Action Mechanism of Action Reference
AGONIST Glucocorticoid receptor agonist Expert PubMed DailyMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference

Related Entries

Scaffolds

Parent
Mixture

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Eye disorders
29.85
Nervous system disorders
13.43
Respiratory, thoracic and mediastinal disorders
11.94
Cardiac disorders
5.97
General disorders and administration site conditions
4.48
Investigations
4.48
Skin and subcutaneous tissue disorders
4.48
Product issues
4.48
Immune system disorders
2.99
Infections and infestations
2.99
Injury, poisoning and procedural complications
2.99
Psychiatric disorders
2.99
Vascular disorders
2.99

Cross References

Resources Reference
ChEBI 78354
ChEMBL CHEMBL1201064
DrugCentral 4647
EPA CompTox DTXSID20191424
FDA SRS 9I50C3I3OK
PubChem 240767
SureChEMBL SCHEMBL43184
ZINC ZINC000004213357
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