LINCOMYCIN HYDROCHLORIDE

Search structure
Trade Names:
Synonyms:
Status: Approved (1964)
Entry Type: Small molecule
Molecule Category: Salt
UNII: M6T05Z2B68
Parent Compound: LINCOMYCIN

Structure
InChI Key POUMFISTNHIPTI-BOMBIWCESA-N
Smile CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)N(C)C1.Cl
InChI
InChI=1S/C18H34N2O6S.ClH/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H/t9-,10-,11+,12-,13+,14-,15-,16-,18-;/m1./s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H37ClN2O7S
Molecular Weight 461.02
AlogP -0.86
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 7.0
Polar Surface Area 122.49
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 27.0

Pharmacology

Action Mechanism of Action Reference
INHIBITOR 70S ribosome inhibitor PubMed PubMed

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

Scaffolds

Parent

Adverse Reactions

SOC By Demographic Distribution
System Organ Classification (SOC)
Relative Frequency (%)
Immune system disorders
26.65
Gastrointestinal disorders
12.03
Skin and subcutaneous tissue disorders
11.75
Infections and infestations
6.59
General disorders and administration site conditions
6.3
Nervous system disorders
5.44
Injury, poisoning and procedural complications
4.87
Vascular disorders
4.3
Cardiac disorders
3.72
Respiratory, thoracic and mediastinal disorders
3.44
Metabolism and nutrition disorders
2.58
Renal and urinary disorders
2.29

Cross References

Resources Reference
ChEBI 6472
ChEMBL CHEMBL3989551
FDA SRS M6T05Z2B68
KEGG C14002
PubChem 71476
SureChEMBL SCHEMBL192963
ZINC ZINC03982483
CONTENTS