LINCOMYCIN

Search structure
Synonyms:
Status: Approved (1964)
Entry Type: Small molecule
Molecule Category: Parent
ATC: J01FF02
UNII: BOD072YW0F

Structure
InChI Key OJMMVQQUTAEWLP-KIDUDLJLSA-N
Smile CCC[C@@H]1C[C@@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O)N(C)C1
InChI
InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1

Physicochemical Descriptors

Property Name Value
Molecular Formula C18H34N2O6S
Molecular Weight 406.55
AlogP -0.86
Hydrogen Bond Acceptor 8.0
Hydrogen Bond Donor 5.0
Number of Rotational Bond 7.0
Polar Surface Area 122.49
Molecular species NEUTRAL
Aromatic Rings 0.0
Heavy Atoms 27.0

Pharmacology

Targets EC50(nM) IC50(nM) Kd(nM) Ki(nM) Inhibition(%)
Enzyme Hydrolase
- - - -
Secreted protein
- - 12000 - -

Indications

Mesh Heading Maximum Phase Mesh ID Reference
Bacterial Infections 4 D001424 ClinicalTrials
Osteomyelitis 0 D010019 ClinicalTrials

Related Entries

MCS

Scaffolds

Salt

Cross References

Resources Reference
CAS NUMBER 154-21-2
ChEBI 6472
ChEMBL CHEMBL1447
DrugBank DB01627
DrugCentral 1582
EPA CompTox DTXSID3023215
FDA SRS BOD072YW0F
Guide to Pharmacology 10941
KEGG C06812
PDB 3QB
PubChem 3000540
SureChEMBL SCHEMBL4010
ZINC ZINC000003982483
CONTENTS