| Trade Names: | |
| Synonyms: | |
| Status: | Approved (1956) |
| Entry Type: | Small molecule |
| Molecule Category: | Salt |
| UNII: | 4956DJR58O |
| Parent Compound: | MECAMYLAMINE |
Structure
| InChI Key | PKVZBNCYEICAQP-UHFFFAOYSA-N |
|---|---|
| Smile | |
| InChI |
|
Physicochemical Descriptors
| Property Name | Value |
|---|---|
| Molecular Formula | C11H22ClN |
| Molecular Weight | 203.76 |
| AlogP | 2.42 |
| Hydrogen Bond Acceptor | 1.0 |
| Hydrogen Bond Donor | 1.0 |
| Number of Rotational Bond | 1.0 |
| Polar Surface Area | 12.03 |
| Molecular species | BASE |
| Aromatic Rings | 0.0 |
| Heavy Atoms | 12.0 |
Pharmacology
| Targets | EC50(nM) | IC50(nM) | Kd(nM) | Ki(nM) | Inhibition(%) | |
|---|---|---|---|---|---|---|
|
Transporter
Electrochemical transporter
SLC superfamily of solute carriers
SLC21/SLCO family of organic anion transporting polypeptides
|
- | - | - | - | 107 |
Indications
| Mesh Heading | Maximum Phase | Mesh ID | Reference |
|---|---|---|---|
| Depressive Disorder | 2 | D003866 | ClinicalTrials |
Related Entries
Scaffolds
Adverse Reactions
Cross References
| Resources | Reference |
|---|---|
| ChEBI | 6707 |
| ChEMBL | CHEMBL1237082 |
| EPA CompTox | DTXSID70896795 |
| FDA SRS | 4956DJR58O |
| Guide to Pharmacology | 3990 |
| KEGG | C07511 |
| PubChem | 13221 |
| SureChEMBL | SCHEMBL123951 |
| ZINC | ZINC38140873 |
CONTENTS