DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved Unknown Unknown Common Cold; Influenza, Human; Respiratory Tract Diseases; Respiratory Tract Infections Histamine H1 receptor antagonist


Small molecule Approved Unknown Unknown Fractures, Bone; Heart Arrest; Kidney Diseases; Lung Neoplasms; Organophosphate Poisoning; Pain; Prostatic Neoplasms, Castration-Resistant; Myalgia; Pancreatic Neoplasms Unknown


Small molecule Approved Unknown Unknown Marijuana Abuse; Cocaine-Related Disorders; Depressive Disorder Unknown


Small molecule Approved Unknown Unknown Desmoplastic Small Round Cell Tumor; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Adenocarcinoma of Lung; Carcinoma, Large Cell; Diffuse Intrinsic Pontine Glioma; Fallopian Tube Neoplasms; Glioma; Head and Neck Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Melanoma; Multiple Myeloma; Ovarian Neoplasms; Rhabdomyosarcoma; Sarcoma; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Hodgkin Disease; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mesothelioma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Neoplasms Unknown

Small molecule

Approved

Unknown

Desmoplastic Small Round Cell Tumor; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Adenocarcinoma of Lung; Carcinoma, Large Cell; Diffuse Intrinsic Pontine Glioma; Fallopian Tube Neoplasms; Glioma; Head and Neck Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Melanoma; Multiple Myeloma; Ovarian Neoplasms; Rhabdomyosarcoma; Sarcoma; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Hodgkin Disease; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mesothelioma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Neoplasms

Unknown


Small molecule Approved OTHER ORAL Cardiovascular Diseases; Hypertension Voltage-gated L-type calcium channel blocker


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Approved Unknown Unknown Opioid-Related Disorders; Alcoholism Unknown


Small molecule Approved Unknown Unknown Ependymoma; Infectious Mononucleosis; Lung Neoplasms; Pancreatic Neoplasms; Paraganglioma; Periodontitis; Prostatic Neoplasms; Astrocytoma; Bipolar Disorder; Cytomegalovirus Infections; Glioblastoma; Glioma; Hepatitis C, Chronic; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Neuralgia, Postherpetic; Post-Acute COVID-19 Syndrome; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Stomatitis, Herpetic; Waldenstrom Macroglobulinemia; Encephalitis; Herpes Simplex; HIV Infections; Neoplasms; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases Unknown

Small molecule

Approved

Unknown

Ependymoma; Infectious Mononucleosis; Lung Neoplasms; Pancreatic Neoplasms; Paraganglioma; Periodontitis; Prostatic Neoplasms; Astrocytoma; Bipolar Disorder; Cytomegalovirus Infections; Glioblastoma; Glioma; Hepatitis C, Chronic; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Neuralgia, Postherpetic; Post-Acute COVID-19 Syndrome; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Stomatitis, Herpetic; Waldenstrom Macroglobulinemia; Encephalitis; Herpes Simplex; HIV Infections; Neoplasms; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases

Unknown


Small molecule Approved GASTROINTESTINAL; OTHER INTRAVENOUS; ORAL Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer; Stomach Ulcer Potassium-transporting ATPase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Duodenal Ulcer; Gastroesophageal Reflux; Heartburn; Peptic Ulcer; Stomach Ulcer

Potassium-transporting ATPase inhibitor


Small molecule Approved CANCER; OTHER ORAL Aging; Breast Diseases; Endometrial Neoplasms; Hypertension; Kallmann Syndrome; Anovulation; Breast Neoplasms, Male; Carcinoma; Endometriosis; Fibrous Dysplasia, Polyostotic; Hypertension, Pulmonary; Hypogonadism; Hypopituitarism; Metabolic Syndrome; Puberty, Precocious; Triple Negative Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Gynecomastia; Klinefelter Syndrome; Ovarian Neoplasms; Breast Neoplasms; Neoplasms Cytochrome P450 19A1 inhibitor

Small molecule

Approved

CANCER; OTHER

ORAL

Aging; Breast Diseases; Endometrial Neoplasms; Hypertension; Kallmann Syndrome; Anovulation; Breast Neoplasms, Male; Carcinoma; Endometriosis; Fibrous Dysplasia, Polyostotic; Hypertension, Pulmonary; Hypogonadism; Hypopituitarism; Metabolic Syndrome; Puberty, Precocious; Triple Negative Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Gynecomastia; Klinefelter Syndrome; Ovarian Neoplasms; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Breast Neoplasms; Neoplasms; Schizophrenia; Stress Disorders, Post-Traumatic; Alzheimer Disease; Atrial Fibrillation; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Breast Neoplasms; Neoplasms; Schizophrenia; Stress Disorders, Post-Traumatic; Alzheimer Disease; Atrial Fibrillation; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis

Sodium channel alpha subunit blocker


Small molecule Approved Unknown Unknown Burns; Glycogen Storage Disease Type III; Migraine Disorders; Neuromyelitis Optica; Alopecia; Rhinitis; Conjunctivitis, Allergic; Dermatitis; Eczema; Multiple Sclerosis; Pemphigus; Pruritus; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Severe Acute Respiratory Syndrome; Eye Manifestations; Hypersensitivity Unknown


Small molecule Approved Unknown Unknown Pre-Eclampsia; Eosinophilic Esophagitis; Non-alcoholic Fatty Liver Disease; Essential Hypertension; Hypertrophy, Left Ventricular; Marfan Syndrome; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Proteinuria; Stroke Type-1 angiotensin II receptor antagonist


Small molecule Approved CARDIOVASCULAR; OTHER INJECTION Unknown HERG blocker


Small molecule Approved Unknown Unknown Arrhythmias, Cardiac Unknown


Small molecule Approved Unknown Unknown Heart Defects, Congenital; Neoplasms; Osteosarcoma; Ganglioneuroblastoma; Leukemia, Myeloid, Acute; Multiple Sclerosis; Myelodysplastic Syndromes; Neuroblastoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Hepatoblastoma; Leukemia; Lymphoma, Large B-Cell, Diffuse; Precursor Cell Lymphoblastic Leukemia-Lymphoma DNA topoisomerase II inhibitor


Small molecule Approved CARDIOVASCULAR; IMMUNE SYSTEM; OTHER ORAL Arthritis, Rheumatoid; beta-Thalassemia; Carcinoma, Renal Cell; DiGeorge Syndrome; Glioblastoma; Gliosarcoma; Hypertension; Lecithin Cholesterol Acyltransferase Deficiency; Leukemia, Lymphoid; Leukemia, Myeloid; Neoplasms, Neuroepithelial; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Autoimmune Diseases; Bronchiolitis Obliterans Syndrome; Burkitt Lymphoma; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Crohn Disease; Epidermolysis Bullosa; Fanconi Anemia; Gout; Granuloma, Lethal Midline; Graves Disease; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinuria; Hepatitis, Alcoholic; Histiocytosis, Langerhans-Cell; HIV Infections; Hyperlipoproteinemia Type I; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunologic Deficiency Syndromes; Kidney Neoplasms; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Mast-Cell; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Leukemia, Prolymphocytic, B-Cell; Leukemia, Prolymphocytic, T-Cell; Liver Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Multiple Sclerosis; Mycosis Fungoides; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Pemphigoid, Benign Mucous Membrane; Pemphigoid, Bullous; Polycythemia Vera; Primary Myelofibrosis; Psoriasis; Renal Insufficiency, Chronic; Scleroderma, Diffuse; Scleroderma, Limited; Scleroderma, Systemic; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Sjogren's Syndrome; Vasculitis; Wiskott-Aldrich Syndrome; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Carcinoma, Hepatocellular; Cardiovascular Diseases; Cystitis, Interstitial; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Hepatitis C; Hodgkin Disease; Kidney Diseases; Kidney Failure, Chronic; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Microscopic Polyangiitis; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasms; Nephrotic Syndrome; Neuromyelitis Optica; Pemphigus; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Red-Cell Aplasia, Pure; Renal Insufficiency; Takayasu Arteritis; Uveitis; Waldenstrom Macroglobulinemia; Delayed Graft Function Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor

Small molecule

Approved

CARDIOVASCULAR; IMMUNE SYSTEM; OTHER

ORAL

Arthritis, Rheumatoid; beta-Thalassemia; Carcinoma, Renal Cell; DiGeorge Syndrome; Glioblastoma; Gliosarcoma; Hypertension; Lecithin Cholesterol Acyltransferase Deficiency; Leukemia, Lymphoid; Leukemia, Myeloid; Neoplasms, Neuroepithelial; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Autoimmune Diseases; Bronchiolitis Obliterans Syndrome; Burkitt Lymphoma; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Crohn Disease; Epidermolysis Bullosa; Fanconi Anemia; Gout; Granuloma, Lethal Midline; Graves Disease; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinuria; Hepatitis, Alcoholic; Histiocytosis, Langerhans-Cell; HIV Infections; Hyperlipoproteinemia Type I; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunologic Deficiency Syndromes; Kidney Neoplasms; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Mast-Cell; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Leukemia, Prolymphocytic, B-Cell; Leukemia, Prolymphocytic, T-Cell; Liver Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Multiple Sclerosis; Mycosis Fungoides; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Pemphigoid, Benign Mucous Membrane; Pemphigoid, Bullous; Polycythemia Vera; Primary Myelofibrosis; Psoriasis; Renal Insufficiency, Chronic; Scleroderma, Diffuse; Scleroderma, Limited; Scleroderma, Systemic; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Sjogren's Syndrome; Vasculitis; Wiskott-Aldrich Syndrome; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Carcinoma, Hepatocellular; Cardiovascular Diseases; Cystitis, Interstitial; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Hepatitis C; Hodgkin Disease; Kidney Diseases; Kidney Failure, Chronic; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Microscopic Polyangiitis; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasms; Nephrotic Syndrome; Neuromyelitis Optica; Pemphigus; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Red-Cell Aplasia, Pure; Renal Insufficiency; Takayasu Arteritis; Uveitis; Waldenstrom Macroglobulinemia; Delayed Graft Function

Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor


Small molecule Approved Unknown Unknown Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Central Nervous System Neoplasms; Ganglioneuroblastoma; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Lymphoma; Neuroblastoma; Sarcoma; Breast Neoplasms; Cardiomyopathies; Extravasation of Diagnostic and Therapeutic Materials DNA topoisomerase II inhibitor

Small molecule

Approved

Unknown

Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Central Nervous System Neoplasms; Ganglioneuroblastoma; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Lymphoma; Neuroblastoma; Sarcoma; Breast Neoplasms; Cardiomyopathies; Extravasation of Diagnostic and Therapeutic Materials

DNA topoisomerase II inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER ORAL Alzheimer Disease; Glioma; Colorectal Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; Carcinoma, Hepatocellular; Diarrhea; Liver Cirrhosis; Tuberculosis; Autoimmune Diseases; Hepatitis; Hepatitis B; Hepatitis B, Chronic; HIV Infections; Infections; Inflammation; Virus Diseases DNA inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER

ORAL

Alzheimer Disease; Glioma; Colorectal Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; Carcinoma, Hepatocellular; Diarrhea; Liver Cirrhosis; Tuberculosis; Autoimmune Diseases; Hepatitis; Hepatitis B; Hepatitis B, Chronic; HIV Infections; Infections; Inflammation; Virus Diseases

DNA inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Angina, Stable; Arthritis, Rheumatoid; Glioblastoma; Vascular Diseases; Breast Neoplasms; Cardiomyopathies; Cocaine-Related Disorders; Epilepsy; Esophageal and Gastric Varices; Hypertension, Pulmonary; Hypoglycemia; Kidney Diseases; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hematologic Neoplasms; Hypercholesterolemia; Hypertension, Portal; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Multiple Myeloma; Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Adrenergic receptor alpha-1 antagonist

Small molecule

Approved

OTHER

ORAL

Angina, Stable; Arthritis, Rheumatoid; Glioblastoma; Vascular Diseases; Breast Neoplasms; Cardiomyopathies; Cocaine-Related Disorders; Epilepsy; Esophageal and Gastric Varices; Hypertension, Pulmonary; Hypoglycemia; Kidney Diseases; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hematologic Neoplasms; Hypercholesterolemia; Hypertension, Portal; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Multiple Myeloma; Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left

Adrenergic receptor alpha-1 antagonist


Small molecule Approved DERMATOLOGY ORAL Osteomyelitis; Bacterial Infections Bacterial 70S ribosome inhibitor


Small molecule Approved Unknown Unknown Osteomyelitis; Pyelonephritis; Bacterial Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved Unknown Unknown Breast Neoplasms; Hepatitis B, Chronic; Aortic Valve Stenosis; Asthma; Bone Resorption; Coronary Stenosis; Fibrous Dysplasia, Polyostotic; HIV Infections; Osteoarthritis; Ovarian Neoplasms; Periodontitis; Bone Diseases, Metabolic; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Bone Diseases Unknown


Small molecule Approved Unknown Unknown Brain Injuries; Reperfusion Injury; Severe Acute Respiratory Syndrome; Subarachnoid Hemorrhage; Hypertension, Pulmonary; Thrombosis Unknown


Small molecule Approved Unknown Unknown Liver Cirrhosis, Biliary; Cardiovascular Diseases Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Atherosclerosis; Coronary Disease; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

INJECTION

Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neoplasms, Plasma Cell; Neuroblastoma; Retinoblastoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia

Reactive metabolite scavenging agent

Small molecule

Approved

Unknown

Alopecia Areata; Anemia, Sickle Cell; Anxiety Disorders; Barrett Esophagus; Breast Carcinoma In Situ; Cardiovascular Diseases; Colonic Neoplasms; Depressive Disorder, Major; Diabetes Insipidus; Diabetic Retinopathy; Glomerulosclerosis, Focal Segmental; Head and Neck Neoplasms; HIV Infections; Li-Fraumeni Syndrome; Liver Diseases; Malaria; Multiple Sclerosis, Chronic Progressive; Muscular Dystrophy, Duchenne; Neuralgia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sleep Apnea, Obstructive; Thoracic Neoplasms; Tuberculosis; Acne Vulgaris; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Adenomatous Polyposis Coli; Aortic Aneurysm, Abdominal; Arthritis, Rheumatoid; Atrial Fibrillation; Bardet-Biedl Syndrome; Blindness; Breast Neoplasms; Burns; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cerebral Palsy; Colitis, Ulcerative; Diabetic Foot; Endocrine Gland Neoplasms; Esophageal Neoplasms; Fibromyalgia; Fragile X Syndrome; Frontotemporal Dementia; Geographic Atrophy; Glioblastoma; Heart Failure; Heart Failure, Systolic; Hemangiosarcoma; Hepatitis; HIV-Associated Lipodystrophy Syndrome; Hypertension, Pulmonary; Inflammatory Bowel Diseases; Intellectual Disability; Leprosy; Leukemia, Lymphocytic, Chronic, B-Cell; Leukoplakia, Oral; Low Back Pain; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Melanoma; Melanosis; Motor Activity; Multiple Myeloma; Multiple Sclerosis; Neoplasms; Neurobehavioral Manifestations; Neuroendocrine Tumors; Ovarian Neoplasms; Pancreatic Neoplasms; Parkinson Disease; Periodontitis; Peripheral Nervous System Diseases; Pregnancy; Prostatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Renal Insufficiency, Chronic; Sarcoidosis; Sex Chromosome Disorders of Sex Development; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Weight Gain; Acute Coronary Syndrome; Aging; Atherosclerosis; Bipolar Disorder; Brain Neoplasms; Cognitive Dysfunction; Colorectal Neoplasms; Coronary Disease; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endometrial Neoplasms; Epilepsy; Fatty Liver; Glaucoma; Glucose Intolerance; Hidradenitis Suppurativa; Huntington Disease; Hypercholesterolemia; Hypertension; Infertility; Insulin Resistance; Intermittent Claudication; Lipid Metabolism Disorders; Liver Neoplasms; Metabolic Diseases; Metabolic Syndrome; Migraine Disorders; Muscular Dystrophies; Non-alcoholic Fatty Liver Disease; Obesity; Osteoarthritis; Peripheral Arterial Disease; Polycystic Kidney, Autosomal Dominant; Polycystic Ovary Syndrome; Post-Acute COVID-19 Syndrome; Prediabetic State; Pre-Eclampsia; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Psychotic Disorders; Reperfusion Injury; Schizophrenia; Sepsis; Severe Acute Respiratory Syndrome; Thyroid Neoplasms; Diabetes Mellitus

Unknown


Small molecule Approved Unknown Unknown Kidney Diseases; Opioid-Related Disorders; Dermatitis, Atopic; Gambling; Non-alcoholic Fatty Liver Disease; Smoking Cessation; Substance-Related Disorders; Alcoholism Unknown


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Hypotension, Orthostatic; Nesidioblastosis; Obesity; Aging; Kidney Neoplasms; Non-alcoholic Fatty Liver Disease; Atherosclerosis; Coronary Disease; Diabetes, Gestational; Hypercholesterolemia; Hypertension; Metabolic Diseases; Metabolic Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2 Maltase-glucoamylase inhibitor

Small molecule

Approved

Unknown

Pancreatitis; Uveal Melanoma; Breast Neoplasms; Carcinoma, Squamous Cell; Depressive Disorder, Major; Hip Fractures; Neoplasms; Osteoarthritis; Rotator Cuff Injuries; Substance Withdrawal Syndrome; Wounds and Injuries; Abdominal Pain; Chronic Pain; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Neuralgia; Opioid-Related Disorders; Osteoarthritis, Knee; Pain

Unknown

Small molecule

Approved

Unknown

Aging; Carcinoma, Squamous Cell; Constriction, Pathologic; Diabetes Mellitus, Type 2; Keloid; Melanoma; Osteoarthritis, Knee; Osteosarcoma; Peripheral Arterial Disease; Wounds and Injuries; Anemia, Sickle Cell; Aortic Valve Insufficiency; Breast Neoplasms; Cardiomyopathy, Hypertrophic; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; HIV Infections; Idiopathic Pulmonary Fibrosis; Inflammation; Neurilemmoma; Neuroma, Acoustic; Pancreatic Neoplasms; Peripheral Nervous System Diseases; Respiratory Distress Syndrome; Sarcopenia; Stress Disorders, Post-Traumatic; Diabetic Nephropathies; Essential Hypertension; Glioblastoma; Glomerulonephritis, IGA; Heart Failure; Hyperoxaluria, Primary; Hypertension; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Kidney Diseases; Marfan Syndrome; Non-alcoholic Fatty Liver Disease; Proteinuria; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases

Unknown


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Brain Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Bile Duct Neoplasms; Central Nervous System Neoplasms; Gallbladder Neoplasms; Klatskin Tumor; Barrett Esophagus; Neoplasms DNA inhibitor