DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PEDIATRICS ORAL Acidosis, Lactic; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; AIDS Dementia Complex; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Neoplasms; Panic Disorder; Anxiety; Anxiety Disorders; Anxiety, Separation; Autistic Disorder; Dementia; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Severe Acute Respiratory Syndrome; Depressive Disorder Unknown


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL HIV Infections; Lecithin Cholesterol Acyltransferase Deficiency; Mental Disorders; Alcoholism; Cocaine-Related Disorders; Cognitive Dysfunction; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neuralgia, Postherpetic; Neurofibromatosis 1; Opioid-Related Disorders; Substance-Related Disorders; Anxiety; Dementia; Epilepsy, Absence; Feeding and Eating Disorders; Mood Disorders; Obesity; Pain; Peripheral Nervous System Diseases; Schizophrenia; Bipolar Disorder; Depressive Disorder; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Lennox Gastaut Syndrome; Seizures Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

HIV Infections; Lecithin Cholesterol Acyltransferase Deficiency; Mental Disorders; Alcoholism; Cocaine-Related Disorders; Cognitive Dysfunction; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Neuralgia, Postherpetic; Neurofibromatosis 1; Opioid-Related Disorders; Substance-Related Disorders; Anxiety; Dementia; Epilepsy, Absence; Feeding and Eating Disorders; Mood Disorders; Obesity; Pain; Peripheral Nervous System Diseases; Schizophrenia; Bipolar Disorder; Depressive Disorder; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Lennox Gastaut Syndrome; Seizures

Sodium channel alpha subunit blocker


Small molecule Approved Unknown Unknown Migraine Disorders; Neuromyelitis Optica; Rhinitis; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pemphigus; Pruritus; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Hypersensitivity Unknown


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Approved Unknown Unknown Anemia, Sickle Cell; Barrett Esophagus; Cardiovascular Diseases; Diabetic Retinopathy; Pulmonary Disease, Chronic Obstructive; Thoracic Neoplasms; Anxiety Disorders; Breast Carcinoma In Situ; Depressive Disorder, Major; Diabetes Insipidus; Head and Neck Neoplasms; HIV Infections; Li-Fraumeni Syndrome; Liver Diseases; Multiple Sclerosis; Muscular Dystrophy, Duchenne; Neuralgia; Osteoarthritis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sleep Apnea, Obstructive; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Adenomatous Polyposis Coli; Aortic Aneurysm, Abdominal; Arthritis, Rheumatoid; Atrial Fibrillation; Bardet-Biedl Syndrome; Blindness; Breast Neoplasms; Burns; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cerebral Palsy; Colitis, Ulcerative; Colonic Neoplasms; Diabetic Foot; Endometrial Hyperplasia; Esophageal Neoplasms; Fragile X Syndrome; Frontotemporal Dementia; Geographic Atrophy; Glioblastoma; Heart Failure, Systolic; Hemangiosarcoma; Hepatitis; HIV-Associated Lipodystrophy Syndrome; Hypertension, Pulmonary; Intellectual Disability; Leukemia, Lymphocytic, Chronic, B-Cell; Low Back Pain; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Melanoma; Multiple Myeloma; Neoplasms; Neurobehavioral Manifestations; Neuroendocrine Tumors; Non-alcoholic Fatty Liver Disease; Ovarian Neoplasms; Pancreatic Neoplasms; Periodontitis; Peripheral Nervous System Diseases; Pregnancy; Prostatic Neoplasms; Rectal Neoplasms; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Sex Chromosome Disorders of Sex Development; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Weight Gain; Aging; Atherosclerosis; Bipolar Disorder; Brain Neoplasms; Cognitive Dysfunction; Colorectal Neoplasms; Coronary Disease; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endometrial Neoplasms; Fatty Liver; Glucose Intolerance; Hidradenitis Suppurativa; Huntington Disease; Hypercholesterolemia; Hypertension; Infertility; Insulin Resistance; Lipid Metabolism Disorders; Liver Neoplasms; Metabolic Diseases; Metabolic Syndrome; Migraine Disorders; Muscular Dystrophies; Obesity; Peripheral Arterial Disease; Polycystic Kidney, Autosomal Dominant; Polycystic Ovary Syndrome; Prediabetic State; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Psychotic Disorders; Schizophrenia; Diabetes Mellitus Unknown

Small molecule

Approved

Unknown

Anemia, Sickle Cell; Barrett Esophagus; Cardiovascular Diseases; Diabetic Retinopathy; Pulmonary Disease, Chronic Obstructive; Thoracic Neoplasms; Anxiety Disorders; Breast Carcinoma In Situ; Depressive Disorder, Major; Diabetes Insipidus; Head and Neck Neoplasms; HIV Infections; Li-Fraumeni Syndrome; Liver Diseases; Multiple Sclerosis; Muscular Dystrophy, Duchenne; Neuralgia; Osteoarthritis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sleep Apnea, Obstructive; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Adenomatous Polyposis Coli; Aortic Aneurysm, Abdominal; Arthritis, Rheumatoid; Atrial Fibrillation; Bardet-Biedl Syndrome; Blindness; Breast Neoplasms; Burns; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cerebral Palsy; Colitis, Ulcerative; Colonic Neoplasms; Diabetic Foot; Endometrial Hyperplasia; Esophageal Neoplasms; Fragile X Syndrome; Frontotemporal Dementia; Geographic Atrophy; Glioblastoma; Heart Failure, Systolic; Hemangiosarcoma; Hepatitis; HIV-Associated Lipodystrophy Syndrome; Hypertension, Pulmonary; Intellectual Disability; Leukemia, Lymphocytic, Chronic, B-Cell; Low Back Pain; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Melanoma; Multiple Myeloma; Neoplasms; Neurobehavioral Manifestations; Neuroendocrine Tumors; Non-alcoholic Fatty Liver Disease; Ovarian Neoplasms; Pancreatic Neoplasms; Periodontitis; Peripheral Nervous System Diseases; Pregnancy; Prostatic Neoplasms; Rectal Neoplasms; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Sex Chromosome Disorders of Sex Development; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Weight Gain; Aging; Atherosclerosis; Bipolar Disorder; Brain Neoplasms; Cognitive Dysfunction; Colorectal Neoplasms; Coronary Disease; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endometrial Neoplasms; Fatty Liver; Glucose Intolerance; Hidradenitis Suppurativa; Huntington Disease; Hypercholesterolemia; Hypertension; Infertility; Insulin Resistance; Lipid Metabolism Disorders; Liver Neoplasms; Metabolic Diseases; Metabolic Syndrome; Migraine Disorders; Muscular Dystrophies; Obesity; Peripheral Arterial Disease; Polycystic Kidney, Autosomal Dominant; Polycystic Ovary Syndrome; Prediabetic State; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Psychotic Disorders; Schizophrenia; Diabetes Mellitus

Unknown


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis Sodium channel alpha subunit blocker

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Breast Neoplasms; Stress Disorders, Post-Traumatic; Alzheimer Disease; Bipolar Disorder; Cerebellar Ataxia; Child Development Disorders, Pervasive; Depressive Disorder; Depressive Disorder, Major; Melanoma; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Muscular Atrophy, Spinal; Obsessive-Compulsive Disorder; Peripheral Nervous System Diseases; Spinal Cord Injuries; Huntington Disease; Multiple System Atrophy; Spinal Cord Diseases; Spinocerebellar Ataxias; Supranuclear Palsy, Progressive; Amyotrophic Lateral Sclerosis

Sodium channel alpha subunit blocker


Small molecule Approved Unknown Unknown Breast Neoplasms; Carcinoma, Squamous Cell; Depressive Disorder, Major; Hip Fractures; Neuralgia; Osteoarthritis; Rotator Cuff Injuries; Substance Withdrawal Syndrome; Wounds and Injuries; Abdominal Pain; Chronic Pain; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Opioid-Related Disorders; Osteoarthritis, Knee; Pain Unknown


Small molecule Approved OTHER ORAL Glioblastoma; Vascular Diseases; Breast Neoplasms; Cocaine-Related Disorders; Epilepsy; Esophageal and Gastric Varices; Hypertension, Pulmonary; Hypoglycemia; Kidney Diseases; Lymphoma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Portal; Hypertrophy, Left Ventricular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Multiple Myeloma; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Adrenergic receptor alpha-1 antagonist

Small molecule

Approved

OTHER

ORAL

Glioblastoma; Vascular Diseases; Breast Neoplasms; Cocaine-Related Disorders; Epilepsy; Esophageal and Gastric Varices; Hypertension, Pulmonary; Hypoglycemia; Kidney Diseases; Lymphoma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Atherosclerosis; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Portal; Hypertrophy, Left Ventricular; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Multiple Myeloma; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left

Adrenergic receptor alpha-1 antagonist


Small molecule Approved Unknown Unknown Ependymoma; Glioma; Infectious Mononucleosis; Lung Neoplasms; Prostatic Neoplasms; Astrocytoma; Bipolar Disorder; Cytomegalovirus Infections; Glioblastoma; Hepatitis C, Chronic; Leukemia, Lymphocytic, Chronic, B-Cell; Neuralgia, Postherpetic; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Stomatitis, Herpetic; Waldenstrom Macroglobulinemia; Encephalitis; Herpes Simplex; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases Unknown

Small molecule

Approved

Unknown

Ependymoma; Glioma; Infectious Mononucleosis; Lung Neoplasms; Prostatic Neoplasms; Astrocytoma; Bipolar Disorder; Cytomegalovirus Infections; Glioblastoma; Hepatitis C, Chronic; Leukemia, Lymphocytic, Chronic, B-Cell; Neuralgia, Postherpetic; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Stomatitis, Herpetic; Waldenstrom Macroglobulinemia; Encephalitis; Herpes Simplex; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Herpes Genitalis; Herpes Labialis; Herpes Zoster; Virus Diseases

Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER ORAL Alzheimer Disease; Lymphoma; Lymphoma, Non-Hodgkin; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; Carcinoma, Hepatocellular; Diarrhea; Liver Cirrhosis; Tuberculosis; Autoimmune Diseases; Hepatitis; Hepatitis B; Hepatitis B, Chronic; HIV Infections; Infections; Inflammation; Virus Diseases DNA inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER

ORAL

Alzheimer Disease; Lymphoma; Lymphoma, Non-Hodgkin; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Acquired Immunodeficiency Syndrome; AIDS-Associated Nephropathy; Carcinoma, Hepatocellular; Diarrhea; Liver Cirrhosis; Tuberculosis; Autoimmune Diseases; Hepatitis; Hepatitis B; Hepatitis B, Chronic; HIV Infections; Infections; Inflammation; Virus Diseases

DNA inhibitor


Small molecule Approved Unknown Unknown Breast Neoplasms; Hepatitis B, Chronic; Aortic Valve Stenosis; Asthma; Coronary Stenosis; Fibrous Dysplasia, Polyostotic; HIV Infections; Osteoarthritis; Ovarian Neoplasms; Periodontitis; Bone Diseases, Metabolic; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Bone Diseases Unknown


Small molecule Approved Unknown Unknown Kidney Diseases; Opioid-Related Disorders; Dermatitis, Atopic; Gambling; Non-alcoholic Fatty Liver Disease; Smoking Cessation; Alcoholism Unknown


Small molecule Approved Unknown Unknown Heart Defects, Congenital; Neoplasms; Osteosarcoma; Ganglioneuroblastoma; Leukemia, Myeloid, Acute; Multiple Sclerosis; Myelodysplastic Syndromes; Neuroblastoma; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Hepatoblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma DNA topoisomerase II inhibitor


Small molecule Unknown Unknown Unknown Small Cell Lung Carcinoma; Carcinoma, Non-Small-Cell Lung; Urinary Bladder Neoplasms; Brain Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Bile Duct Neoplasms; Central Nervous System Neoplasms; Gallbladder Neoplasms; Klatskin Tumor; Neoplasms DNA inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER INJECTION Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Retinoblastoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Nasopharyngeal Neoplasms; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia Reactive metabolite scavenging agent

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

INJECTION

Chordoma; Fanconi Anemia; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myeloproliferative Disorders; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Retinoblastoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Hodgkin Disease; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Squamous Cell; Hepatoblastoma; Lung Neoplasms; Multiple Myeloma; Nasopharyngeal Neoplasms; Peripheral Nervous System Diseases; Trigeminal Neuralgia; Head and Neck Neoplasms; Ovarian Neoplasms; Xerostomia

Reactive metabolite scavenging agent


Small molecule Unknown Unknown Unknown Hypertension Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Peripheral Arterial Disease; Aging; Constriction, Pathologic; Diabetes Mellitus, Type 2; Melanoma; Osteoarthritis, Knee; Osteosarcoma; Wounds and Injuries; Anemia, Sickle Cell; Cardiomyopathy, Hypertrophic; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; HIV Infections; Idiopathic Pulmonary Fibrosis; Inflammation; Pancreatic Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Stress Disorders, Post-Traumatic; Diabetic Nephropathies; Essential Hypertension; Glioblastoma; Glomerulonephritis, IGA; Heart Failure; Hyperoxaluria, Primary; Hypertension; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Kidney Diseases; Marfan Syndrome; Non-alcoholic Fatty Liver Disease; Proteinuria; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases Unknown

Small molecule

Approved

Unknown

Peripheral Arterial Disease; Aging; Constriction, Pathologic; Diabetes Mellitus, Type 2; Melanoma; Osteoarthritis, Knee; Osteosarcoma; Wounds and Injuries; Anemia, Sickle Cell; Cardiomyopathy, Hypertrophic; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glomerulosclerosis, Focal Segmental; HIV Infections; Idiopathic Pulmonary Fibrosis; Inflammation; Pancreatic Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Stress Disorders, Post-Traumatic; Diabetic Nephropathies; Essential Hypertension; Glioblastoma; Glomerulonephritis, IGA; Heart Failure; Hyperoxaluria, Primary; Hypertension; Hypertension, Pulmonary; Hypertrophy, Left Ventricular; Kidney Diseases; Marfan Syndrome; Non-alcoholic Fatty Liver Disease; Proteinuria; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases

Unknown


Small molecule Approved DERMATOLOGY; OTHER TOPICAL Dermatitis, Perioral; Dermatitis, Seborrheic; Acne Vulgaris; Erythema; Rosacea Unknown


Small molecule Unknown Unknown Unknown Osteomyelitis; Pyelonephritis; Bacterial Infections; Bronchitis, Chronic; Otitis Media Bacterial penicillin-binding protein inhibitor


Small molecule Unknown Unknown Unknown Colorectal Neoplasms; Heart Diseases; Inflammation; Postoperative Complications; Acute Kidney Injury; Alcohol-Related Disorders; Brain Injuries; Breast Neoplasms; Delirium; Hernias, Diaphragmatic, Congenital; Lung Neoplasms; Myocardial Infarction; Obesity; Obesity, Morbid; Opioid-Related Disorders; Renal Insufficiency; Shock, Septic; Subarachnoid Hemorrhage; Tonsillitis; Back Pain; Coronary Disease; Esophageal Neoplasms; Fluoride Poisoning; Intracranial Aneurysm; Neoplasms; Pain; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Insufficiency; Severe Acute Respiratory Syndrome GABA-A receptor; anion channel positive allosteric modulator

Small molecule

Unknown

Colorectal Neoplasms; Heart Diseases; Inflammation; Postoperative Complications; Acute Kidney Injury; Alcohol-Related Disorders; Brain Injuries; Breast Neoplasms; Delirium; Hernias, Diaphragmatic, Congenital; Lung Neoplasms; Myocardial Infarction; Obesity; Obesity, Morbid; Opioid-Related Disorders; Renal Insufficiency; Shock, Septic; Subarachnoid Hemorrhage; Tonsillitis; Back Pain; Coronary Disease; Esophageal Neoplasms; Fluoride Poisoning; Intracranial Aneurysm; Neoplasms; Pain; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Insufficiency; Severe Acute Respiratory Syndrome

GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved Unknown Unknown Brain Injuries; Reperfusion Injury; Severe Acute Respiratory Syndrome; Subarachnoid Hemorrhage; Hypertension, Pulmonary; Kidney Diseases; Thrombosis Unknown


Small molecule Approved CARDIOVASCULAR; OTHER INJECTION Unknown HERG blocker


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Hypotension, Orthostatic; Nesidioblastosis; Obesity; Aging; Non-alcoholic Fatty Liver Disease; Atherosclerosis; Coronary Disease; Diabetes, Gestational; Hypercholesterolemia; Hypertension; Metabolic Diseases; Metabolic Syndrome; Diabetes Mellitus; Diabetes Mellitus, Type 2 Maltase-glucoamylase inhibitor


Small molecule Unknown Unknown Unknown Alcoholism Opioid receptors; mu/kappa/delta antagonist

Small molecule

Approved

GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Cystic Fibrosis; Laryngopharyngeal Reflux; Neoplasms; Pain; Endometrial Neoplasms; Eosinophilic Esophagitis; Leukemia, Lymphocytic, Chronic, B-Cell; Premature Birth; Pseudomyxoma Peritonei; Rectal Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Diabetes Mellitus, Type 1; Duodenal Ulcer; Esophagitis, Peptic; Gastritis; Gout; Helicobacter Infections; Idiopathic Pulmonary Fibrosis; Lymphoma; Osteoarthritis; Gastroesophageal Reflux; Peptic Ulcer; Stomach Ulcer

Potassium-transporting ATPase inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Atherosclerosis; Coronary Disease; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker


Small molecule Approved Unknown Unknown Arrhythmias, Cardiac Unknown


Small molecule Unknown Unknown Unknown Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Central Nervous System Neoplasms; Inflammatory Breast Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Lymphoma; Sarcoma; Breast Neoplasms; Cardiomyopathies Unknown


Small molecule Approved DERMATOLOGY ORAL Osteomyelitis; Bacterial Infections Bacterial 70S ribosome inhibitor

Small molecule

Approved

CARDIOVASCULAR; IMMUNE SYSTEM; OTHER

ORAL

Neoplasms, Neuroepithelial; Arthritis, Rheumatoid; beta-Thalassemia; Carcinoma, Renal Cell; DiGeorge Syndrome; Gliosarcoma; Hypertension; Lecithin Cholesterol Acyltransferase Deficiency; Lymphoma, T-Cell; Pancreatic Neoplasms; Scleroderma, Diffuse; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Anemia, Sickle Cell; Autoimmune Diseases; Burkitt Lymphoma; Chemical and Drug Induced Liver Injury; Crohn Disease; Epidermolysis Bullosa; Fanconi Anemia; Gout; Granuloma, Lethal Midline; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinuria, Paroxysmal; Hepatitis, Alcoholic; Histiocytosis, Langerhans-Cell; HIV Infections; Hyperlipoproteinemia Type I; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Mast-Cell; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Leukemia, Prolymphocytic, B-Cell; Leukemia, Prolymphocytic, T-Cell; Liver Diseases; Lymphoma; Lymphoma, Follicular; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Multiple Sclerosis; Mycosis Fungoides; Myeloproliferative Disorders; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Pemphigoid, Benign Mucous Membrane; Pemphigoid, Bullous; Polycythemia Vera; Primary Myelofibrosis; Psoriasis; Purpura, Schoenlein-Henoch; Scleroderma, Limited; Scleroderma, Systemic; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Sjogren's Syndrome; Vasculitis; Wiskott-Aldrich Syndrome; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Carcinoma, Hepatocellular; Cardiovascular Diseases; Cystitis, Interstitial; Cytomegalovirus Infections; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Hepatitis C; Hodgkin Disease; Kidney Diseases; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Microscopic Polyangiitis; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasms; Nephrotic Syndrome; Neuromyelitis Optica; Pemphigus; Polyradiculopathy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Red-Cell Aplasia, Pure; Renal Insufficiency; Renal Insufficiency, Chronic; Sarcoidosis, Pulmonary; Takayasu Arteritis; Uveitis; Waldenstrom Macroglobulinemia

Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor

Small molecule

Approved

CANCER; OTHER

ORAL

Hypertension; Aging; Endometrial Neoplasms; Kallmann Syndrome; Anovulation; Breast Neoplasms, Male; Carcinoma; Endometriosis; Fibrous Dysplasia, Polyostotic; Hypertension, Pulmonary; Hypogonadism; Hypopituitarism; Metabolic Syndrome; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Triple Negative Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Gynecomastia; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor