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Total: 6532
Small molecule
Approved
Unknown
Unknown
Hypertension
Angiotensin-converting enzyme inhibitor
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Pyelonephritis; Bacterial Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Brain Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Bile Duct Neoplasms; Central Nervous System Neoplasms; Gallbladder Neoplasms; Klatskin Tumor; Barrett Esophagus; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Fallopian Tube Neoplasms; Gynecomastia; Ovarian Neoplasms; Peritoneal Neoplasms; Puberty, Precocious; Salivary Gland Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Carcinoma; Neoplasms
Androgen Receptor antagonist
Small molecule
Approved
Unknown
Unknown
Alopecia Areata; Anemia, Sickle Cell; Anxiety Disorders; Barrett Esophagus; Breast Carcinoma In Situ; Cardiovascular Diseases; Colonic Neoplasms; Depressive Disorder, Major; Diabetes Insipidus; Diabetic Retinopathy; Glomerulosclerosis, Focal Segmental; Head and Neck Neoplasms; HIV Infections; Li-Fraumeni Syndrome; Liver Diseases; Malaria; Multiple Sclerosis, Chronic Progressive; Muscular Dystrophy, Duchenne; Neuralgia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sleep Apnea, Obstructive; Thoracic Neoplasms; Tuberculosis; Acne Vulgaris; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Adenomatous Polyposis Coli; Aortic Aneurysm, Abdominal; Arthritis, Rheumatoid; Atrial Fibrillation; Bardet-Biedl Syndrome; Blindness; Breast Neoplasms; Burns; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cerebral Palsy; Colitis, Ulcerative; Diabetic Foot; Endocrine Gland Neoplasms; Esophageal Neoplasms; Fibromyalgia; Fragile X Syndrome; Frontotemporal Dementia; Geographic Atrophy; Glioblastoma; Heart Failure; Heart Failure, Systolic; Hemangiosarcoma; Hepatitis; HIV-Associated Lipodystrophy Syndrome; Hypertension, Pulmonary; Inflammatory Bowel Diseases; Intellectual Disability; Leprosy; Leukemia, Lymphocytic, Chronic, B-Cell; Leukoplakia, Oral; Low Back Pain; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Melanoma; Melanosis; Motor Activity; Multiple Myeloma; Multiple Sclerosis; Neoplasms; Neurobehavioral Manifestations; Neuroendocrine Tumors; Ovarian Neoplasms; Pancreatic Neoplasms; Parkinson Disease; Periodontitis; Peripheral Nervous System Diseases; Pregnancy; Prostatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Renal Insufficiency, Chronic; Sarcoidosis; Sex Chromosome Disorders of Sex Development; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Weight Gain; Acute Coronary Syndrome; Aging; Atherosclerosis; Bipolar Disorder; Brain Neoplasms; Cognitive Dysfunction; Colorectal Neoplasms; Coronary Disease; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endometrial Neoplasms; Epilepsy; Fatty Liver; Glaucoma; Glucose Intolerance; Hidradenitis Suppurativa; Huntington Disease; Hypercholesterolemia; Hypertension; Infertility; Insulin Resistance; Intermittent Claudication; Lipid Metabolism Disorders; Liver Neoplasms; Metabolic Diseases; Metabolic Syndrome; Migraine Disorders; Muscular Dystrophies; Non-alcoholic Fatty Liver Disease; Obesity; Osteoarthritis; Peripheral Arterial Disease; Polycystic Kidney, Autosomal Dominant; Polycystic Ovary Syndrome; Post-Acute COVID-19 Syndrome; Prediabetic State; Pre-Eclampsia; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Psychotic Disorders; Reperfusion Injury; Schizophrenia; Sepsis; Severe Acute Respiratory Syndrome; Thyroid Neoplasms; Diabetes Mellitus
Unknown
Small molecule
Approved
Unknown
Unknown
Amyotrophic Lateral Sclerosis; Cystic Fibrosis; Lymphoma; Muscular Atrophy, Spinal; Myelodysplastic-Myeloproliferative Diseases; Myelodysplastic Syndromes; Argininosuccinic Aciduria; HIV Infections; Huntington Disease; Leukemia; Machado-Joseph Disease; Pyruvate Dehydrogenase Complex Deficiency Disease; Tuberculosis, Pulmonary; Carbamoyl-Phosphate Synthase I Deficiency Disease; Citrullinemia; Hyperammonemia; Ornithine Carbamoyltransferase Deficiency Disease; Urea Cycle Disorders, Inborn
Glutamine sequestering agent
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Nasal Obstruction
Unknown
Small molecule
Approved
Unknown
Unknown
Acquired Immunodeficiency Syndrome; Infections; Tuberculosis; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
OTHER
INJECTION
Argininosuccinic Aciduria; Carbamoyl-Phosphate Synthase I Deficiency Disease; Citrullinemia; Ornithine Carbamoyltransferase Deficiency Disease; Carcinoma, Hepatocellular; Hand-Foot Syndrome; Head and Neck Neoplasms; Non-alcoholic Fatty Liver Disease; Pain; Psoriasis; Skin Diseases; Cicatrix; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Radiodermatitis
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Diabetes Mellitus, Type 1; Diabetes Mellitus; Diabetes Mellitus, Type 2
Lysosomal alpha-glucosidase inhibitor
Small molecule
Approved
OTHER
INJECTION
Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Bile Duct Neoplasms; Biliary Tract Diseases; Bone Neoplasms; Carcinoma, Large Cell; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Esthesioneuroblastoma, Olfactory; Gastrointestinal Stromal Tumors; Glioma; Head and Neck Neoplasms; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Genital Neoplasms, Female; Granuloma, Lethal Midline; Hepatoblastoma; Hernia; Hernia, Ventral; Hodgkin Disease; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms
Unknown
Small molecule
Approved
RESPIRATORY
ORAL
Osteomyelitis; Bacterial Infections
Bacterial DNA gyrase inhibitor
Small molecule
Approved
Unknown
ORAL
Hepatitis C, Chronic; Infertility, Male; Hepatitis C; Hyperoxaluria, Primary; Non-alcoholic Fatty Liver Disease; Obesity; Syringomyelia; Xerostomia; Depressive Disorder; Homocystinuria
Betaine-homocysteine S-methyltransferase substrate
Small molecule
Approved
Unknown
Unknown
Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Abdominal Pain; Otitis Media; Colorectal Neoplasms; Diarrhea; Dyspepsia; Infertility
Antifoaming agent
Small molecule
Approved
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Dopamine transporter releasing agent
Small molecule
Approved
Unknown
Unknown
Breath Tests; Helicobacter Infections
Diagnostic agent
Small molecule
Approved
Unknown
TOPICAL
Herpes Labialis; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Acute Coronary Syndrome; Aortic Valve Insufficiency; Cardiomyopathy, Hypertrophic; Diabetic Nephropathies; Nephritis, Hereditary; Peripheral Arterial Disease; Renal Insufficiency, Chronic; Atherosclerosis; Atrial Fibrillation; Chagas Cardiomyopathy; Coronary Disease; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Pulmonary; Kidney Diseases; Lipid Metabolism Disorders; Metabolic Syndrome; Non-ST Elevated Myocardial Infarction; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke; Ventricular Dysfunction, Left
Type-1 angiotensin II receptor antagonist
Small molecule
Approved
EYE; IMMUNE SYSTEM; OTHER
INJECTION
Condylomata Acuminata; Herpes Simplex; HIV Infections; Kidney Diseases; Uterine Cervical Neoplasms; Infections; Papilloma; Sarcoma; Uterine Cervical Dysplasia; Anus Neoplasms; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Primary Immunodeficiency Diseases; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Osteomyelitis; Communicable Diseases; Hematologic Neoplasms; Enterobacteriaceae Infections; Pneumonia, Ventilator-Associated; Pyelonephritis; Shock, Septic; Urinary Tract Infections; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Narcolepsy
Dopamine transporter releasing agent
Small molecule
Approved
OTHER
OPHTHALMIC
Alopecia Areata; Meniere Disease; Vitiligo; Glaucoma; Glaucoma, Open-Angle; Hypertension; Ocular Hypertension
Prostanoid FP receptor agonist
Small molecule
Approved
Unknown
Unknown
Premature Birth; Sleep Apnea, Obstructive; Sleep Apnea Syndromes; Brain Neoplasms; Obesity, Morbid; Respiratory Insufficiency; Breast Diseases; Ear Neoplasms; Heart Diseases; Intelligence; Neoplasms; Neuralgia, Postherpetic; Opioid-Related Disorders; Pain; Shock, Septic; Stroke
Unknown
Small molecule
Approved
Unknown
Unknown
Arthritis, Rheumatoid; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms; Dermatitis, Atopic; Edema; Gastroesophageal Reflux; Rhinitis, Allergic, Perennial; Asthma; Diabetic Nephropathies; Pruritus; Rhinitis, Allergic, Seasonal; Hypersensitivity
Unknown
Small molecule
Approved
OTHER
INTRAMUSCULAR; ORAL
Dyskinesia, Drug-Induced; Lecithin Cholesterol Acyltransferase Deficiency; Mood Disorders; Weight Loss; Amyotrophic Lateral Sclerosis; Anorexia Nervosa; Autistic Disorder; Delirium; Opioid-Related Disorders; Vomiting; Alcoholism; Anorexia; Anxiety; Borderline Personality Disorder; Dementia; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Developmental Disabilities; Feeding and Eating Disorders; Gambling; Genital Neoplasms, Female; Huntington Disease; Intellectual Disability; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Testicular Neoplasms; Weight Gain; Bipolar Disorder; Depressive Disorder, Major; Mental Disorders; Psychomotor Agitation; Psychotic Disorders; Schizophrenia
D2-like dopamine receptor antagonist
Small molecule
Approved
Unknown
Unknown
Carcinoid Tumor; Desmoplastic Small Round Cell Tumor; Diffuse Intrinsic Pontine Glioma; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liver Neoplasms; Mesothelioma; Oligodendroglioma; Pulmonary Disease, Chronic Obstructive; Adenocarcinoma; Astrocytoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Bone Neoplasms; Carcinoma; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangiosarcoma; Kidney Neoplasms; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Ovarian Neoplasms; Paraganglioma; Peritoneal Neoplasms; Pinealoma; Rhabdomyosarcoma; Sarcoma; Wilms Tumor; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Ganglioneuroblastoma; Hepatoblastoma; Lung Neoplasms; Neoplasm Metastasis; Neuroblastoma; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Neoplasms
Unknown
Small molecule
Approved
GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
INJECTION; INTRAVENOUS
Gram-Negative Bacterial Infections; Osteomyelitis; Pancreatitis; Respiratory Insufficiency; Appendicitis; Communicable Diseases; Hematologic Neoplasms; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Lung Diseases; Mental Disorders; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Urinary Bladder Neoplasms; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Stomach Diseases; Alcoholism; Amphetamine-Related Disorders; Anorexia; Anorexia Nervosa; Cachexia; Cocaine-Related Disorders; Fibromyalgia; Paraganglioma; Substance-Related Disorders; Weight Loss; Anxiety; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders
Adrenergic receptor alpha-2 antagonist
Small molecule
Approved
Unknown
Unknown
Fasciitis, Plantar; Hernia, Inguinal; Rib Fractures; Sinusitis; Appendicitis; Joint Diseases; Leiomyoma; Neoplasms; Osteoarthritis; Postoperative Nausea and Vomiting; Pregnancy; Rotator Cuff Injuries; Shoulder Pain; Stress Disorders, Post-Traumatic; Abdominal Pain; Analgesia; Breast Neoplasms; Chronic Pain; Fractures, Bone; Genital Neoplasms, Male; Hallux Valgus; Hypotension; Knee Injuries; Osteoarthritis, Knee; Ovarian Cysts; Ovarian Neoplasms; Pain; Paralysis; Stomach Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Astrocytoma; Carcinoma, Renal Cell; Carcinoma, Small Cell; Desmoplastic Small Round Cell Tumor; Fibroma; Fibrosarcoma; Genital Neoplasms, Female; Glioma; Histiocytoma; Liposarcoma, Myxoid; Lymphoma; Melanoma; Meningeal Neoplasms; Meningitis, Aseptic; Myoepithelioma; Neoplasms, Plasma Cell; Oligodendroglioma; Paraganglioma; Rectal Neoplasms; Sarcoma, Clear Cell; Severe Acute Respiratory Syndrome; Triple Negative Breast Neoplasms; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Central Nervous System Neoplasms; Colonic Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Mediastinal Neoplasms; Medulloblastoma; Multiple Myeloma; Peritoneal Neoplasms; Rhabdomyosarcoma; Sarcoma; Sarcoma, Ewing; Uterine Neoplasms; Wilms Tumor; Carcinoma, Non-Small-Cell Lung; Ganglioneuroblastoma; Lung Neoplasms; Neoplasms; Neuroblastoma; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinoblastoma; Small Cell Lung Carcinoma; Uterine Cervical Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Myositis, Inclusion Body; Neuroblastoma; beta-Thalassemia; Brain Neoplasms; HIV Infections; Maple Syrup Urine Disease; Tuberculosis, Pulmonary
Unknown
Small molecule
Approved
Unknown
Unknown
Status Epilepticus; Epilepsy
Unknown
Small molecule
Approved
Unknown
Unknown
Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Hypersensitivity; Nasal Obstruction
Unknown