DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved Unknown Unknown Premature Birth; Sleep Apnea, Obstructive; Sleep Apnea Syndromes; Brain Neoplasms; Obesity, Morbid; Respiratory Insufficiency; Breast Diseases; Ear Neoplasms; Heart Diseases; Intelligence; Neoplasms; Neuralgia, Postherpetic; Opioid-Related Disorders; Pain; Shock, Septic; Stroke Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER DENTAL; TOPICAL Stomatitis; Lung Diseases, Obstructive Phosphodiesterase 4 inhibitor


Small molecule Approved Unknown Unknown Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Hypersensitivity; Nasal Obstruction Unknown


Small molecule Approved Unknown Unknown Tinea Pedis Unknown


Small molecule Approved OTHER ORAL HIV Infections; Alzheimer Disease; Dermatitis; Melanoma; Psoriasis Retinoid receptor agonist


Small molecule Approved OTHER; RESPIRATORY ORAL Breast Neoplasms; Hypersensitivity; Ovarian Neoplasms; Asthma; Lung Diseases, Obstructive Cysteinyl leukotriene receptor 1 antagonist


Small molecule Approved DERMATOLOGY; OTHER TOPICAL Skin Diseases; Molluscum Contagiosum; Acne Vulgaris Retinoic acid receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Stomach Diseases; Alcoholism; Amphetamine-Related Disorders; Anorexia; Anorexia Nervosa; Cachexia; Cocaine-Related Disorders; Fibromyalgia; Paraganglioma; Substance-Related Disorders; Weight Loss; Anxiety; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders Adrenergic receptor alpha-2 antagonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Stomach Diseases; Alcoholism; Amphetamine-Related Disorders; Anorexia; Anorexia Nervosa; Cachexia; Cocaine-Related Disorders; Fibromyalgia; Paraganglioma; Substance-Related Disorders; Weight Loss; Anxiety; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders

Adrenergic receptor alpha-2 antagonist


Small molecule Approved Unknown Unknown Melanoma; Muscle Spasticity; Pain Unknown


Small molecule Approved CANCER; OTHER; PREGNANCY AND GYNECOLOGY INJECTION; INTRAVENOUS Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Neoplasms, Plasma Cell; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Prostatic Neoplasms; Stomach Neoplasms Tubulin inhibitor

Small molecule

Approved

CANCER; OTHER; PREGNANCY AND GYNECOLOGY

INJECTION; INTRAVENOUS

Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Neoplasms, Plasma Cell; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Prostatic Neoplasms; Stomach Neoplasms

Tubulin inhibitor


Small molecule Approved OTHER ORAL Prostatic Neoplasms, Castration-Resistant; Neoplasms; Prostatic Neoplasms Androgen Receptor antagonist


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved EYE; OTHER; UROLOGY AND KIDNEY INJECTION; OPHTHALMIC; ORAL Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Bronchitis; Cataract; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Influenza, Human; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Severe Acute Respiratory Syndrome; Skin Diseases; Staphylococcal Infections; Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; Infections; Pneumonia; Respiratory Tract Infections; Sinusitis; Urinary Tract Infections DNA gyrase inhibitor

Small molecule

Approved

EYE; OTHER; UROLOGY AND KIDNEY

INJECTION; OPHTHALMIC; ORAL

Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Bronchitis; Cataract; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Influenza, Human; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Severe Acute Respiratory Syndrome; Skin Diseases; Staphylococcal Infections; Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; Infections; Pneumonia; Respiratory Tract Infections; Sinusitis; Urinary Tract Infections

DNA gyrase inhibitor


Small molecule Approved Unknown Unknown Arthritis, Rheumatoid; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms; Dermatitis, Atopic; Edema; Gastroesophageal Reflux; Rhinitis, Allergic, Perennial; Asthma; Diabetic Nephropathies; Pruritus; Rhinitis, Allergic, Seasonal; Hypersensitivity Unknown


Small molecule Approved OTHER; RESPIRATORY ORAL Anemia, Sickle Cell; Inflammation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Acne Vulgaris; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Tobacco Use Disorder; Pulmonary Disease, Chronic Obstructive; Asthma Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Infections; Osteomyelitis; Pouchitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudomonas Infections; Appendicitis; Neonatal Sepsis; Neoplasms; Pneumonia, Bacterial; Gonorrhea; Staphylococcal Infections; Urinary Tract Infections; Bacterial Infections Unknown


Small molecule Approved OTHER INTRAMUSCULAR; ORAL Dyskinesia, Drug-Induced; Lecithin Cholesterol Acyltransferase Deficiency; Mood Disorders; Weight Loss; Amyotrophic Lateral Sclerosis; Anorexia Nervosa; Autistic Disorder; Delirium; Opioid-Related Disorders; Vomiting; Alcoholism; Anorexia; Anxiety; Borderline Personality Disorder; Dementia; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Developmental Disabilities; Feeding and Eating Disorders; Gambling; Genital Neoplasms, Female; Huntington Disease; Intellectual Disability; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Testicular Neoplasms; Weight Gain; Bipolar Disorder; Depressive Disorder, Major; Mental Disorders; Psychomotor Agitation; Psychotic Disorders; Schizophrenia D2-like dopamine receptor antagonist

Small molecule

Approved

OTHER

INTRAMUSCULAR; ORAL

Dyskinesia, Drug-Induced; Lecithin Cholesterol Acyltransferase Deficiency; Mood Disorders; Weight Loss; Amyotrophic Lateral Sclerosis; Anorexia Nervosa; Autistic Disorder; Delirium; Opioid-Related Disorders; Vomiting; Alcoholism; Anorexia; Anxiety; Borderline Personality Disorder; Dementia; Depressive Disorder; Depressive Disorder, Treatment-Resistant; Developmental Disabilities; Feeding and Eating Disorders; Gambling; Genital Neoplasms, Female; Huntington Disease; Intellectual Disability; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Testicular Neoplasms; Weight Gain; Bipolar Disorder; Depressive Disorder, Major; Mental Disorders; Psychomotor Agitation; Psychotic Disorders; Schizophrenia

D2-like dopamine receptor antagonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Bulimia Nervosa; Cognitive Dysfunction; Feeding and Eating Disorders; Hernias, Diaphragmatic, Congenital; HIV Infections; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Deafness; Diabetes Mellitus; Hearing Loss, Sudden; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Mood Disorders; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures Carbonic anhydrase II inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS

ORAL

Bulimia Nervosa; Cognitive Dysfunction; Feeding and Eating Disorders; Hernias, Diaphragmatic, Congenital; HIV Infections; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Deafness; Diabetes Mellitus; Hearing Loss, Sudden; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Mood Disorders; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures

Carbonic anhydrase II inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL Amyotrophic Lateral Sclerosis; Anus Neoplasms; Erectile Dysfunction; Glioblastoma; Glioma; Hypertension; Hypertension, Pulmonary; Insulin Resistance; Kidney Diseases; Liver Diseases; Malaria; Neoplasm Metastasis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Tuberculosis; Hepatitis B, Chronic; Mycobacterium avium-intracellulare Infection; Neoplasms; Post-Acute COVID-19 Syndrome; Pregnancy; Sarcoma; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Coronavirus Infections; Hepatitis D; Infections; Influenza, Human; Pneumonia; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Virus Diseases Cytochrome P450 3A inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL

Amyotrophic Lateral Sclerosis; Anus Neoplasms; Erectile Dysfunction; Glioblastoma; Glioma; Hypertension; Hypertension, Pulmonary; Insulin Resistance; Kidney Diseases; Liver Diseases; Malaria; Neoplasm Metastasis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Tuberculosis; Hepatitis B, Chronic; Mycobacterium avium-intracellulare Infection; Neoplasms; Post-Acute COVID-19 Syndrome; Pregnancy; Sarcoma; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Coronavirus Infections; Hepatitis D; Infections; Influenza, Human; Pneumonia; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Virus Diseases

Cytochrome P450 3A inhibitor


Small molecule Approved Unknown Unknown Hepatopulmonary Syndrome; Hypotension, Orthostatic; Ischemic Stroke; Ascites; Hypotension; Shock, Septic; Spinal Cord Injuries; Cardiovascular Diseases Unknown


Small molecule Approved Unknown TOPICAL Herpes Labialis; Virus Diseases Human herpesvirus 1 DNA polymerase inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Hemorrhagic Fever, Ebola; Marfan Syndrome; Acute Kidney Injury; Atrial Fibrillation; Ehlers-Danlos Syndrome; Essential Hypertension; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Heart Failure; Hepatitis C, Chronic; Hypercholesterolemia; Myocardial Ischemia; Renal Insufficiency, Chronic; Sepsis; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypertension; Kidney Failure, Chronic Type-1 angiotensin II receptor antagonist

Small molecule

Approved

Unknown

Hemorrhagic Fever, Ebola; Marfan Syndrome; Acute Kidney Injury; Atrial Fibrillation; Ehlers-Danlos Syndrome; Essential Hypertension; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Heart Failure; Hepatitis C, Chronic; Hypercholesterolemia; Myocardial Ischemia; Renal Insufficiency, Chronic; Sepsis; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypertension; Kidney Failure, Chronic

Type-1 angiotensin II receptor antagonist


Small molecule Approved Unknown Unknown Hyperprolactinemia; Cocaine-Related Disorders; Fibromyalgia; Stroke; Unverricht-Lundborg Syndrome; Restless Legs Syndrome; Parkinson Disease Unknown


Small molecule Approved Unknown Unknown Alcoholism; Cocaine-Related Disorders; Sleep Apnea, Obstructive; Anxiety; Schizophrenia; Epilepsy Unknown

Small molecule

Approved

Unknown

Amphetamine-Related Disorders; Cocaine-Related Disorders; Dyskinesia, Drug-Induced; Renal Insufficiency, Chronic; Alcoholism; Anorexia Nervosa; Attention Deficit Disorder with Hyperactivity; Depression, Postpartum; Marijuana Abuse; Obsessive-Compulsive Disorder; Parkinson Disease; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Anxiety; Bipolar Disorder; Borderline Personality Disorder; Cognitive Dysfunction; Delirium; Dementia; Depressive Disorder; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Mental Disorders; Mood Disorders; Phobia, Social; Schizophrenia; Psychotic Disorders

Unknown


Small molecule Approved Unknown Unknown Prostatic Neoplasms; Alzheimer Disease; Endometrial Neoplasms; Menopause; Severe Acute Respiratory Syndrome; Bone Diseases, Metabolic; Breast Neoplasms; Cognitive Dysfunction; Osteoporosis; Osteoporosis, Postmenopausal; Polycystic Ovary Syndrome; Psychotic Disorders; Schizophrenia Estrogen receptor modulator


Small molecule Approved OTHER INJECTION Bacterial Infections Bacterial DNA gyrase inhibitor

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Brain Neoplasms; Carcinoma, Endometrioid; Carcinoma, Non-Small-Cell Lung; Leiomyoma; Lymphoma, Non-Hodgkin; Mesothelioma; Pregnancy, Ectopic; Adenomyosis; Anovulation; Carcinoma; Carcinoma, Lobular; Dwarfism; Endometriosis; Fallopian Tube Neoplasms; Hemangiosarcoma; Hermanski-Pudlak Syndrome; Infertility, Male; Inflammatory Breast Neoplasms; Leiomyosarcoma; Liver Neoplasms; Lymphangioleiomyomatosis; Peritoneal Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Abortion, Spontaneous; Azoospermia; Carcinoma, Intraductal, Noninfiltrating; Endometrial Neoplasms; Follicular Cyst; Hereditary Breast and Ovarian Cancer Syndrome; Hypogonadism; Infertility; Menopause; Neoplasm Metastasis; Osteoporosis; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Polycystic Ovary Syndrome; Pregnancy; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor


Small molecule Approved OTHER OPHTHALMIC Conjunctivitis, Allergic Histamine H1 receptor antagonist


Small molecule Approved Unknown Unknown Pain Unknown

Small molecule

Approved

OTHER

ORAL

Lecithin Cholesterol Acyltransferase Deficiency; Multiple Sclerosis; Alcoholism; Anxiety; Anxiety Disorders; Borderline Personality Disorder; Brain Concussion; Dementia; Depressive Disorder; Neurotic Disorders; Obsessive-Compulsive Disorder; Phobia, Social; Psychomotor Agitation; Psychotic Disorders; Stress Disorders, Post-Traumatic; Bipolar Disorder; Depressive Disorder, Major; Schizophrenia

Dopamine D2 receptor antagonist


Small molecule Approved Unknown Unknown Lymphoma, T-Cell, Cutaneous; Idiopathic Pulmonary Fibrosis; Skin Diseases; Skin Neoplasms; Acne Vulgaris; Hypopigmentation; Lentigo; Psoriasis Retinoic acid receptor agonist


Small molecule Approved Unknown Unknown Osteomyelitis; Bacterial Infections Bacterial DNA gyrase inhibitor