Display Options:
Total: 6532
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Diabetes Mellitus; Diabetes Mellitus, Type 2
Sulfonylurea receptor 1, Kir6.2 blocker
Small molecule
Approved
Unknown
Unknown
Unknown
Voltage-sensitive sodium channel alpha-subunit blocker
Small molecule
Approved
Unknown
Unknown
Pregnancy; Diabetes Mellitus; Bipolar Disorder; Graves Disease; Hypothyroidism; Congenital Hypothyroidism; Lipid Metabolism Disorders
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Cocaine-Related Disorders; Hearing Loss, Noise-Induced; Tobacco Use Disorder; Essential Tremor; Hearing Loss; Migraine Disorders; Obesity; Parkinson Disease; Alcoholism; Epilepsy, Complex Partial; Feeding and Eating Disorders; Psychotic Disorders; Schizophrenia; Smoking Cessation; Weight Gain; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
Unknown
Unknown
Unknown
Cytochrome P450 inhibitor
Small molecule
Unknown
Unknown
Unknown
Acquired Immunodeficiency Syndrome; Brain Neoplasms; Carcinoma, Basal Cell; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Colorectal Neoplasms; Gliosarcoma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanoma; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Breast Neoplasms; Carcinoma, Hepatocellular; Endometrial Neoplasms; Graft vs Host Disease; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Lung Neoplasms; Lupus Erythematosus, Systemic; Lymphoma; Multiple Myeloma; Neuroblastoma; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Leukemia, Promyelocytic, Acute; Neoplasms
Thioredoxin reductase 1 inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
IMMUNE SYSTEM
TOPICAL
Herpes Simplex; Virus Diseases
Envelope glycoprotein inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Xerostomia
Unknown
Small molecule
Approved
OTHER
INTRAVENOUS; ORAL
Burns; Cystic Fibrosis; Meningitis; Abscess; Cellulitis; Gram-Positive Bacterial Infections; Optic Nerve Diseases; Pneumonia, Bacterial; Pneumonia, Pneumococcal; Skin Diseases; Staphylococcal Infections; Tuberculosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Bacteremia; Bacterial Infections; Infections; Osteomyelitis; Pneumonia
Bacterial 70S ribosome inhibitor
Small molecule
Approved
Unknown
Unknown
Hepatitis C; Insulin Resistance; Respiratory Distress Syndrome; Tuberculosis; Coronavirus Infections; Infections; Pregnancy; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Severe Acute Respiratory Syndrome; HIV Infections
Human immunodeficiency virus type 1 protease inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS
ORAL
Neoplasms; Multiple Sclerosis; Aggression; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Neuralgia; Psychomotor Agitation; Schizophrenia; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
MUSCULOSKELETAL; OTHER
ORAL
Lupus Erythematosus, Systemic; Dysmenorrhea; Pharyngitis; Toothache; Low Back Pain; Migraine Disorders; Pain; Prostatic Neoplasms; Shoulder Pain; Spondylitis, Ankylosing; Tuberculosis; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases
Cyclooxygenase-2 inhibitor
Small molecule
Approved
EYE
OPHTHALMIC
Macular Degeneration; Retinitis Pigmentosa; Glaucoma
Unknown
Small molecule
Approved
CARDIOVASCULAR; HEMATOLOGY; OTHER
INJECTION; INTRAVENOUS
Angina, Unstable; Ischemic Stroke; Thrombocytopenia; Thrombosis
Thrombin inhibitor
Small molecule
Approved
Unknown
Unknown
Gastroesophageal Reflux; Malaria, Falciparum; Malaria
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Carcinoma, Intraductal, Noninfiltrating; Tobacco Use Disorder; Anxiety; Breast Neoplasms, Male; Diabetes Mellitus; Persian Gulf Syndrome; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Adenomyosis; Alcoholism; Alzheimer Disease; Bipolar Disorder; Borderline Personality Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Serous Chorioretinopathy; Cocaine-Related Disorders; Endometrial Neoplasms; Endometriosis; Fallopian Tube Neoplasms; Hepatitis C; HIV Infections; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Stress Disorders, Post-Traumatic; Abortion, Spontaneous; Depressive Disorder; Depressive Disorder, Major; Leiomyoma; Meningioma; Pituitary ACTH Hypersecretion; Cushing Syndrome
Glucocorticoid receptor antagonist
Small molecule
Approved
Unknown
Unknown
Acute Coronary Syndrome; Aspergillosis; Bacterial Infections; Multiple Sclerosis; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Esophagitis; Gastrinoma; Helicobacter Infections; Prostatic Neoplasms, Castration-Resistant; Schizophrenia; Zollinger-Ellison Syndrome; Barrett Esophagus; Diabetes Mellitus; Esophageal Diseases; Gastrointestinal Hemorrhage; Heart Failure; Hemorrhage; Laryngopharyngeal Reflux; Ulcer; Gastroesophageal Reflux; Peptic Ulcer
Unknown
Small molecule
Approved
Unknown
Unknown
Constipation; Heartburn
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Anemia, Sickle Cell; Malaria
Dihydrofolate reductase inhibitor
Small molecule
Approved
HEMATOLOGY; OTHER; UROLOGY AND KIDNEY
INTRAVENOUS
Renal Insufficiency; Hematologic Neoplasms; Hypertension, Pulmonary; Anemia; Anemia, Iron-Deficiency; Renal Insufficiency, Chronic
Unknown
Small molecule
Approved
EYE
INJECTION
Central Nervous System Neoplasms; Glioblastoma; Melanoma; Pleural Effusion; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Histoplasmosis; Pancreatic Neoplasms; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Macular Degeneration; Myopia, Degenerative; Retinal Neovascularization; Wet Macular Degeneration
DNA inhibitor
Small molecule
Approved
Unknown
TOPICAL
Nausea; Communicable Diseases; Acromegaly; Anemia; Arthritis, Psoriatic; Arthritis, Rheumatoid; Burns; Colitis, Ulcerative; Constipation; Eczema; Infections; Multiple Sclerosis; Prostatic Neoplasms; Psoriasis; Spondylitis, Ankylosing
Unknown
Small molecule
Unknown
Unknown
Unknown
Pain; Bipolar Disorder; Congenital Hypothyroidism; Hypothyroidism; Thyroid Neoplasms
Thyroid hormone receptor agonist
Small molecule
Approved
Unknown
Unknown
Irritable Bowel Syndrome; Digestive System Diseases
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
TRANSDERMAL
Amphetamine-Related Disorders; Cocaine-Related Disorders; Down Syndrome; Substance-Related Disorders; Anxiety; Brain Injuries; Cognitive Dysfunction; Delirium; Dementia, Vascular; Depressive Disorder; Neurobehavioral Manifestations; Schizophrenia; Supranuclear Palsy, Progressive; Alzheimer Disease; Dementia; Parkinson Disease
Cholinesterases; ACHE & BCHE inhibitor
Small molecule
Approved
Unknown
ORAL
Bulimia; Bulimia Nervosa; Depressive Disorder; Hidradenitis Suppurativa; Premenstrual Syndrome; Dysmenorrhea; Polycystic Ovary Syndrome; Acne Vulgaris
Mineralocorticoid receptor antagonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Non-Small-Cell Lung; Common Cold; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pruritus; Rhinitis, Allergic, Perennial; Hypersensitivity; Rhinitis, Allergic, Seasonal; Urticaria
Histamine H1 receptor antagonist
Small molecule
Approved
OTHER
ORAL
Cystic Fibrosis; Diabetes Mellitus, Type 2; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infertility, Female; Leukemia, Lymphocytic, Chronic, B-Cell; Non-alcoholic Fatty Liver Disease; Bulimia; Bulimia Nervosa; Depressive Disorder; Endometrial Neoplasms; Hidradenitis Suppurativa; Hyperandrogenism; Metrorrhagia; Osteoporosis; Premenstrual Syndrome; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Migraine Disorders; Neural Tube Defects; Polycystic Ovary Syndrome; Pregnancy; Turner Syndrome; Acne Vulgaris; Neoplasms
Estrogen receptor alpha agonist
Small molecule
Approved
Unknown
Unknown
Opioid-Related Disorders; Substance-Related Disorders; Cardiovascular Diseases; Autistic Disorder; Borderline Personality Disorder; Depressive Disorder, Major; Mood Disorders; Phobia, Social; Anxiety; Bipolar Disorder; Dementia; Depressive Disorder; Schizophrenia; Psychotic Disorders
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Urinary Tract Infections; Bronchitis, Chronic; Infections; Pharyngitis; Tonsillitis
Bacterial penicillin-binding protein inhibitor
Small molecule
Unknown
Unknown
Unknown
Diabetes Mellitus; Fever; Glaucoma; Heart Failure; Mitral Valve Stenosis; Pancreatic Neoplasms; Asthma; Hepatopulmonary Syndrome; Hernias, Diaphragmatic, Congenital; Hypoplastic Left Heart Syndrome; Liver Cirrhosis; Melanoma; Pulmonary Disease, Chronic Obstructive; Diabetes Mellitus, Type 2; Eisenmenger Complex; Heart Septal Defects, Atrial; Idiopathic Pulmonary Fibrosis; Optic Neuropathy, Ischemic; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Heart Defects, Congenital; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension
Endothelin receptor, ET-A/ET-B antagonist