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Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved Unknown Unknown Unknown Diagnostic


Small molecule Approved CANCER; OTHER INJECTION; INTRAVENOUS Digestive System Diseases; Gastrointestinal Stromal Tumors; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Diseases; Lymphoma, T-Cell, Cutaneous; Melanoma; Myelodysplastic Syndromes; Neuroblastoma; Triple Negative Breast Neoplasms; Anus Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Klatskin Tumor; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Esophageal Neoplasms; Gallbladder Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Neoplasms DNA inhibitor

Small molecule

Approved

CANCER; OTHER

INJECTION; INTRAVENOUS

Digestive System Diseases; Gastrointestinal Stromal Tumors; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Diseases; Lymphoma, T-Cell, Cutaneous; Melanoma; Myelodysplastic Syndromes; Neuroblastoma; Triple Negative Breast Neoplasms; Anus Neoplasms; Bile Duct Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Klatskin Tumor; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Esophageal Neoplasms; Gallbladder Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Neoplasms

DNA inhibitor


Small molecule Approved OTHER; PEDIATRICS ORAL Albinism; Alkaptonuria; Tyrosinemias 4-hydroxyphenylpyruvate dioxygenase inhibitor


Small molecule Approved OTHER ORAL Common Cold; Infections; Respiratory Tract Infections; Cough; Fever; Headache; Sinusitis Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL HIV Infections; Irritable Bowel Syndrome; Kidney Diseases; Liver Diseases; Bronchiolitis; Crohn Disease; Diabetes Mellitus, Type 2; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Sexually Transmitted Diseases; Tuberculosis; Arthritis, Rheumatoid; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Amebiasis; Diarrhea Pyruvate:ferredoxin oxidoreductase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL

HIV Infections; Irritable Bowel Syndrome; Kidney Diseases; Liver Diseases; Bronchiolitis; Crohn Disease; Diabetes Mellitus, Type 2; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Sexually Transmitted Diseases; Tuberculosis; Arthritis, Rheumatoid; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Amebiasis; Diarrhea

Pyruvate:ferredoxin oxidoreductase inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Constipation; Irritable Bowel Syndrome Serotonin 4 (5-HT4) receptor partial agonist


Small molecule Approved OTHER ORAL HIV Infections; Prostatic Neoplasms, Castration-Resistant; Hepatitis C, Chronic; Hepatitis D; Non-alcoholic Fatty Liver Disease; Aortic Valve Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Metabolic Syndrome; Metabolism, Inborn Errors; Myocardial Infarction; Cardiovascular Diseases; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II Niemann-Pick C1-like protein 1 inhibitor

Small molecule

Approved

OTHER

ORAL

HIV Infections; Prostatic Neoplasms, Castration-Resistant; Hepatitis C, Chronic; Hepatitis D; Non-alcoholic Fatty Liver Disease; Aortic Valve Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Metabolic Syndrome; Metabolism, Inborn Errors; Myocardial Infarction; Cardiovascular Diseases; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II

Niemann-Pick C1-like protein 1 inhibitor


Small molecule Approved OTHER ORAL Hepatitis C; Insulin Resistance; Tuberculosis; Liver Cirrhosis, Biliary; Multiple Sclerosis; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic; Infections; Severe Acute Respiratory Syndrome; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved Unknown Unknown Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Hypersensitivity Unknown


Small molecule Approved OTHER ORAL Angioedema; Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria Histamine H1 receptor antagonist


Small molecule Approved Unknown Unknown Hypersensitivity Unknown


Small molecule Approved Unknown ORAL Diabetes Mellitus, Type 1; Hematologic Neoplasms; Severe Acute Respiratory Syndrome; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Constipation; Multiple Sclerosis; Kidney Calculi; Prostatitis; Urinary Bladder, Neurogenic; Urinary Retention; Prostatic Hyperplasia Unknown


Small molecule Approved Unknown Unknown Dermatitis, Atopic Unknown


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY ORAL Astrocytoma; Depressive Disorder, Major; Glioblastoma; Head and Neck Neoplasms; Heart Failure; Muscular Dystrophies; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Pancreatic Neoplasms; Priapism; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Premature Ejaculation; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension Phosphodiesterase 5A inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY

ORAL

Astrocytoma; Depressive Disorder, Major; Glioblastoma; Head and Neck Neoplasms; Heart Failure; Muscular Dystrophies; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Pancreatic Neoplasms; Priapism; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Premature Ejaculation; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension

Phosphodiesterase 5A inhibitor


Small molecule Approved OTHER ORAL Unknown Voltage-gated L-type calcium channel blocker


Small molecule Approved Unknown Unknown Abdominal Pain; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Hematologic Neoplasms; Multiple Myeloma; Neoplasm Metastasis; Osteonecrosis; Osteoporosis; Osteoporosis, Postmenopausal; Pain Unknown


Small molecule Approved Unknown Unknown Central Nervous System Diseases; Central Nervous System Neoplasms; Depressive Disorder, Major; Glioma; Neoplasms; Obesity; Tobacco Use Disorder; Alcohol Drinking; Alcoholism; Amyotrophic Lateral Sclerosis; Autistic Disorder; Cocaine-Related Disorders; Fragile X Syndrome; Glioblastoma; Heroin Dependence; Huntington Disease; Lupus Erythematosus, Systemic; Neuralgia; Opioid-Related Disorders; Psychotic Disorders; Trichotillomania; Alzheimer Disease; Anxiety; Bipolar Disorder; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depressive Disorder; Fibromyalgia; Glaucoma, Open-Angle; Ischemic Stroke; Migraine Disorders; Multiple Sclerosis; Obsessive-Compulsive Disorder; Pain; Parkinson Disease; Schizophrenia; Substance-Related Disorders; Tension-Type Headache; Dementia Unknown

Small molecule

Approved

Unknown

Central Nervous System Diseases; Central Nervous System Neoplasms; Depressive Disorder, Major; Glioma; Neoplasms; Obesity; Tobacco Use Disorder; Alcohol Drinking; Alcoholism; Amyotrophic Lateral Sclerosis; Autistic Disorder; Cocaine-Related Disorders; Fragile X Syndrome; Glioblastoma; Heroin Dependence; Huntington Disease; Lupus Erythematosus, Systemic; Neuralgia; Opioid-Related Disorders; Psychotic Disorders; Trichotillomania; Alzheimer Disease; Anxiety; Bipolar Disorder; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depressive Disorder; Fibromyalgia; Glaucoma, Open-Angle; Ischemic Stroke; Migraine Disorders; Multiple Sclerosis; Obsessive-Compulsive Disorder; Pain; Parkinson Disease; Schizophrenia; Substance-Related Disorders; Tension-Type Headache; Dementia

Unknown


Small molecule Approved Unknown Unknown Hypoglycemia; Rhinoscleroma; Helicobacter Infections; Peritonitis; Bacterial Infections Unknown


Small molecule Approved Unknown Unknown Gastroesophageal Reflux Potassium-transporting ATPase inhibitor


Small molecule Approved CANCER; GASTROINTESTINAL; OTHER INTRAVENOUS; ORAL Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting Neurokinin 1 receptor antagonist

Small molecule

Approved

CANCER; GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting

Neurokinin 1 receptor antagonist


Small molecule Approved CANCER ORAL Carcinoma; Carcinoma, Renal Cell; Nasopharyngeal Carcinoma; Pancreatic Neoplasms; Prostatic Neoplasms; Bile Duct Neoplasms; Breast Neoplasms, Male; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Breast Neoplasms; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Lung Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms Epidermal growth factor receptor erbB1 inhibitor

Small molecule

Approved

CANCER

ORAL

Carcinoma; Carcinoma, Renal Cell; Nasopharyngeal Carcinoma; Pancreatic Neoplasms; Prostatic Neoplasms; Bile Duct Neoplasms; Breast Neoplasms, Male; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Kidney Neoplasms; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Breast Neoplasms; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Lung Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms

Epidermal growth factor receptor erbB1 inhibitor


Small molecule Approved OTHER ORAL Diarrhea; Neuronal Ceroid-Lipofuscinoses; Cystic Fibrosis; HIV Infections; Spastic Paraplegia, Hereditary; Gangliosidoses, GM2; Glycogen Storage Disease; Niemann-Pick Disease, Type C; Sandhoff Disease; Gaucher Disease; Glycogen Storage Disease Type II; Niemann-Pick Diseases Ceramide glucosyltransferase inhibitor


Small molecule Approved Unknown Unknown Unknown Radioactive metals chelating agent


Small molecule Approved OTHER INTRAVENOUS; IV (INFUSION) Meningitis; Renal Insufficiency, Chronic; Sepsis; Hematologic Neoplasms; Meningitis, Pneumococcal; Cross Infection; Diabetic Foot; Osteomyelitis; Pneumonia, Bacterial; Renal Insufficiency; Skin Diseases; Staphylococcal Infections; Bacteremia; Bacterial Infections; Endocarditis; Endocarditis, Bacterial; Gram-Positive Bacterial Infections; Infections; Skin Diseases, Bacterial; Soft Tissue Infections Cell membrane inhibitor

Small molecule

Approved

OTHER

INTRAVENOUS; IV (INFUSION)

Meningitis; Renal Insufficiency, Chronic; Sepsis; Hematologic Neoplasms; Meningitis, Pneumococcal; Cross Infection; Diabetic Foot; Osteomyelitis; Pneumonia, Bacterial; Renal Insufficiency; Skin Diseases; Staphylococcal Infections; Bacteremia; Bacterial Infections; Endocarditis; Endocarditis, Bacterial; Gram-Positive Bacterial Infections; Infections; Skin Diseases, Bacterial; Soft Tissue Infections

Cell membrane inhibitor


Small molecule Approved OTHER TOPICAL Candidiasis, Vulvovaginal; Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved Unknown Unknown Reperfusion Injury; Cystic Fibrosis; Prostatic Hyperplasia; Raynaud Disease; Tinnitus; Urinary Bladder, Overactive; Hypertension, Pulmonary; Erectile Dysfunction Unknown

Small molecule

Approved

Unknown

Anemia; Anemia, Sickle Cell; Angioedemas, Hereditary; Asthma; Carcinoma, Non-Small-Cell Lung; Craniocerebral Trauma; Crohn Disease; Diabetes Mellitus, Type 2; Endotoxemia; Friedreich Ataxia; Hypertriglyceridemia; Immune System Diseases; Lupus Erythematosus, Systemic; Malaria; Melanoma; Metabolic Diseases; Neoplasms; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Syncytial Virus Infections; Skin Diseases; Amnesia; Arthritis, Rheumatoid; Breast Neoplasms; Burns; Cerebral Hemorrhage; Colitis, Ulcerative; Depressive Disorder; Diabetes Mellitus; Diabetic Neuropathies; Endometrial Neoplasms; Hepatitis C; Ischemia; Myocardial Infarction; Orthomyxoviridae Infections; Ovarian Neoplasms; Periodontitis; Pre-Eclampsia; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Renal Artery Obstruction; Sepsis; Tuberculosis, Pulmonary; Venous Thromboembolism; Acute Coronary Syndrome; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Aortic Valve Stenosis; Atherosclerosis; Cardiomyopathy, Dilated; Colorectal Neoplasms; Coronary Artery Disease; Coronary Disease; Heart Failure; Hip Fractures; HIV Infections; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type III; Hypertension; Ischemic Stroke; Lipid Metabolism Disorders; Metabolic Syndrome; Necrosis; Non-alcoholic Fatty Liver Disease; Obesity; Renal Insufficiency; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Stroke; Cardiovascular Diseases

Unknown

Small molecule

Approved

CANCER

INJECTION; INTRAVENOUS; SUBCUTANEOUS; UNKNOWN

Anemia, Refractory, with Excess of Blasts; Astrocytoma; Burkitt Lymphoma; Carcinoma, Medullary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Immunoblastic Lymphadenopathy; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Muscular Dystrophies; Mycosis Fungoides; Myeloproliferative Disorders; Neuroblastoma; Oligodendroglioma; Peritoneal Neoplasms; Sezary Syndrome; Smoldering Multiple Myeloma; Uremia; Adenocarcinoma, Follicular; Adenocarcinoma of Lung; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases of the Nervous System; Breast Neoplasms; Bronchiolitis Obliterans; Bronchiolitis Obliterans Syndrome; Carcinoma, Adenoid Cystic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Castleman Disease; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Glioblastoma; Gliosarcoma; Graft vs Host Disease; Head and Neck Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Immune System Diseases; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Plasma Cell; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lung Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Plasma Cell; Neuromyelitis Optica; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Red-Cell Aplasia, Pure; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; Amyloidosis; Amyloidosis, Familial; Cholangiocarcinoma; Immunoglobulin Light-chain Amyloidosis; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Sarcoma, Myeloid; Waldenstrom Macroglobulinemia; Neoplasms

26S proteasome inhibitor


Small molecule Approved Unknown Unknown Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Melanoma; Vomiting; Brain Neoplasms; Breast Neoplasms; Glioma; Multiple Myeloma; Stomach Neoplasms; Neoplasms; Postoperative Nausea and Vomiting; Strabismus; Nausea Unknown

Small molecule

Approved

OTHER

INHALATION

Asthma; Humeral Fractures; Myocardial Infarction; Heart Arrest; Lung Neoplasms; Multiple Organ Failure; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Scleroderma, Systemic; Raynaud Disease; Respiratory Distress Syndrome; Shock, Septic; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis

Prostanoid IP receptor agonist


Small molecule Approved OTHER; UROLOGY AND KIDNEY ORAL Pulmonary Disease, Chronic Obstructive; Schizophrenia; Urinary Bladder, Overactive; Urinary Incontinence, Urge Muscarinic acetylcholine receptor M2 antagonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Marijuana Abuse; Anxiety Disorders; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved Unknown Unknown Constipation Unknown