Display Options:
Total: 6532
Small molecule
Approved
Unknown
Unknown
Migraine with Aura; Migraine without Aura; Migraine Disorders
Unknown
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS
Raynaud Disease; Diabetic Foot; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis
Prostanoid IP receptor agonist
Small molecule
Approved
CANCER
INTRAMUSCULAR
Carcinoma, Ductal; Carcinoma, Squamous Cell; Colorectal Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Lymphoma; Lymphoma, Non-Hodgkin; Mesothelioma; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fibrous Dysplasia, Polyostotic; Genital Neoplasms, Female; Hypertension, Pulmonary; Lung Neoplasms; Lupus Erythematosus, Systemic; Ovarian Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Endometrial Stromal; Uterine Neoplasms; Carcinoma, Lobular; Neoplasm Metastasis; Breast Neoplasms; Neoplasms
Estrogen receptor antagonist
Small molecule
Approved
OTHER
ORAL
Common Cold; Infections; Respiratory Tract Infections; Cough; Fever; Headache; Sinusitis
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER; PEDIATRICS
ORAL
HIV Infections; Bronchiolitis; Crohn Disease; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Tuberculosis; Amebiasis; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Diarrhea
Pyruvate:ferredoxin oxidoreductase inhibitor
Small molecule
Approved
CARDIOVASCULAR; OTHER
ORAL
Diabetes Mellitus, Type 2; Atrial Fibrillation; Breast Neoplasms; Central Serous Chorioretinopathy; Diabetic Nephropathies; Hyperparathyroidism, Primary; Cardiomyopathies; Essential Hypertension; Muscular Dystrophy, Duchenne; Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Stroke
Mineralocorticoid receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Melanoma; Vomiting; Brain Neoplasms; Breast Neoplasms; Glioma; Multiple Myeloma; Stomach Neoplasms; Neoplasms; Postoperative Nausea and Vomiting; Strabismus; Nausea
Unknown
Small molecule
Approved
Unknown
Unknown
Constipation; Multiple Sclerosis; Kidney Calculi; Prostatitis; Urinary Bladder, Neurogenic; Urinary Retention; Prostatic Hyperplasia
Unknown
Small molecule
Approved
OTHER
ORAL
Hepatitis C; Insulin Resistance; Tuberculosis; Liver Cirrhosis, Biliary; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic; Infections; Severe Acute Respiratory Syndrome; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
Unknown
ORAL
Diabetes Mellitus, Type 1; Hematologic Neoplasms; Severe Acute Respiratory Syndrome; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Hypersensitivity
Unknown
Small molecule
Approved
Unknown
Unknown
Hypersensitivity
Unknown
Small molecule
Approved
OTHER
TOPICAL
Candidiasis, Vulvovaginal; Tinea Pedis
Cytochrome P450 51 inhibitor
Small molecule
Approved
OTHER
ORAL
Angioedema; Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria
Histamine H1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Radioactive metals chelating agent
Small molecule
Approved
OTHER
INTRAVENOUS; IV (INFUSION)
Meningitis; Renal Insufficiency, Chronic; Sepsis; Meningitis, Pneumococcal; Bacteremia; Diabetic Foot; Endocarditis, Bacterial; Gram-Positive Bacterial Infections; Osteomyelitis; Pneumonia, Bacterial; Renal Insufficiency; Skin Diseases; Staphylococcal Infections; Bacterial Infections; Endocarditis; Infections
Cell membrane inhibitor
Small molecule
Approved
CANCER; GASTROINTESTINAL; OTHER
INTRAVENOUS; ORAL
Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting
Neurokinin 1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Reperfusion Injury; Cystic Fibrosis; Prostatic Hyperplasia; Raynaud Disease; Tinnitus; Urinary Bladder, Overactive; Hypertension, Pulmonary; Erectile Dysfunction
Unknown
Small molecule
Approved
CANCER
INJECTION; INTRAVENOUS; SUBCUTANEOUS; UNKNOWN
Myeloproliferative Disorders; Anemia, Refractory, with Excess of Blasts; Astrocytoma; Burkitt Lymphoma; Carcinoma, Medullary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Glioblastoma; Immunoblastic Lymphadenopathy; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Muscular Dystrophies; Mycosis Fungoides; Neuroblastoma; Oligodendroglioma; Peritoneal Neoplasms; Sezary Syndrome; Smoldering Multiple Myeloma; Uremia; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma, Follicular; Adenocarcinoma of Lung; Breast Neoplasms; Bronchiolitis Obliterans; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Castleman Disease; Central Nervous System Neoplasms; Colorectal Neoplasms; Encephalitis, Japanese; Esophageal Neoplasms; Glioma; Gliosarcoma; Graft vs Host Disease; Head and Neck Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Immune System Diseases; Kidney Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Plasma Cell; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neuromyelitis Optica; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Red-Cell Aplasia, Pure; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Amyloidosis; Amyloidosis, Familial; Cholangiocarcinoma; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Sarcoma, Myeloid; Waldenstrom Macroglobulinemia; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasms
26S proteosome inhibitor
Small molecule
Approved
Unknown
Unknown
Dermatitis, Atopic
Unknown
Small molecule
Approved
Unknown
Unknown
Rhinoscleroma; Hypoglycemia; Helicobacter Infections; Peritonitis; Bacterial Infections
Unknown
Small molecule
Approved
OTHER
ORAL
Cystic Fibrosis; HIV Infections; Spastic Paraplegia, Hereditary; Gangliosidoses, GM2; Glycogen Storage Disease; Glycogen Storage Disease Type II; Niemann-Pick Disease, Type C; Sandhoff Disease; Gaucher Disease
Ceramide glucosyltransferase inhibitor
Small molecule
Approved
Unknown
Unknown
Friedreich Ataxia; Anemia; Angioedemas, Hereditary; Asthma; Carcinoma, Non-Small-Cell Lung; Craniocerebral Trauma; Crohn Disease; Diabetes Mellitus, Type 2; Hypertriglyceridemia; Immune System Diseases; Lupus Erythematosus, Systemic; Malaria; Melanoma; Metabolic Diseases; Neoplasms; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Syncytial Virus Infections; Skin Diseases; Amnesia; Arthritis, Rheumatoid; Breast Neoplasms; Burns; Cerebral Hemorrhage; Colitis, Ulcerative; Depressive Disorder; Diabetes Mellitus; Diabetic Neuropathies; Endometrial Hyperplasia; Endometrial Neoplasms; Hepatitis C; Ischemia; Myocardial Infarction; Orthomyxoviridae Infections; Ovarian Neoplasms; Periodontitis; Pre-Eclampsia; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Renal Artery Obstruction; Sepsis; Tuberculosis, Pulmonary; Venous Thromboembolism; Acute Coronary Syndrome; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Aortic Valve Stenosis; Atherosclerosis; Cardiomyopathy, Dilated; Colorectal Neoplasms; Coronary Artery Disease; Coronary Disease; Heart Failure; Hip Fractures; HIV Infections; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type III; Hypertension; Lipid Metabolism Disorders; Metabolic Syndrome; Necrosis; Obesity; Renal Insufficiency; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Stroke; Cardiovascular Diseases
Unknown
Small molecule
Unknown
Unknown
Unknown
Gastroesophageal Reflux
Potassium-transporting ATPase inhibitor
Small molecule
Approved
Unknown
Unknown
Glioma; Central Nervous System Diseases; Depressive Disorder, Major; Obesity; Tobacco Use Disorder; Alcohol Drinking; Alcoholism; Amyotrophic Lateral Sclerosis; Autistic Disorder; Cocaine-Related Disorders; Cognitive Dysfunction; Glioblastoma; Heroin Dependence; Huntington Disease; Lupus Erythematosus, Systemic; Neuralgia; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Psychotic Disorders; Trichotillomania; Alzheimer Disease; Anxiety; Bipolar Disorder; Child Development Disorders, Pervasive; Depressive Disorder; Fibromyalgia; Glaucoma, Open-Angle; Ischemic Stroke; Migraine Disorders; Multiple Sclerosis; Pain; Parkinson Disease; Schizophrenia; Substance-Related Disorders; Tension-Type Headache; Dementia
Unknown
Small molecule
Approved
CANCER
ORAL
Carcinoma, Renal Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Breast Neoplasms, Male; Carcinoma; Carcinoma, Hepatocellular; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Kidney Neoplasms; Leukemia, Myeloid, Acute; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenocarcinoma of Lung; Breast Neoplasms; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Lung Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
Unknown
Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY
ORAL
Head and Neck Neoplasms; Muscular Dystrophies; Astrocytoma; Glioblastoma; Heart Failure; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Priapism; Scleroderma, Systemic; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension
Phosphodiesterase 5A inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Voltage-gated L-type calcium channel blocker
Small molecule
Approved
Unknown
Unknown
Abdominal Pain; Bone Neoplasms; Breast Neoplasms; Hematologic Neoplasms; Multiple Myeloma; Neoplasm Metastasis; Osteonecrosis; Osteoporosis; Osteoporosis, Postmenopausal; Pain; Bone Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Unknown
Small molecule
Approved
Unknown
Unknown
Amphetamine-Related Disorders; Autistic Disorder; Tinnitus; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Feeding and Eating Disorders; Fragile X Syndrome; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Alcoholism
Unknown
Small molecule
Approved
Unknown
Unknown
Alcoholism; Brain Injuries; Hallucinations; Erectile Dysfunction; Parkinson Disease
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Marijuana Abuse; Anxiety Disorders; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders
GABA-A receptor; anion channel positive allosteric modulator