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Total: 6532
Small molecule
Approved
Unknown
Unknown
Urinary Incontinence, Urge; Prostatic Hyperplasia; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence
Unknown
Small molecule
Approved
HEMATOLOGY; OTHER
INTRAVENOUS; SUBCUTANEOUS
Brain Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Ependymoma; Esophageal Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Lymphoma, Non-Hodgkin; Myelodysplastic-Myeloproliferative Diseases; Osteosarcoma; Ovarian Neoplasms; Tuberculosis; beta-Thalassemia; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Glioma; Hematologic Neoplasms; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Myeloma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Anemia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms; Thrombocytopenia
DNA (cytosine-5)-methyltransferase 1 inhibitor
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION
Renal Insufficiency; Cystic Fibrosis; Neoplasms; Spinal Cord Injuries; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive
Muscarinic acetylcholine receptor M3 antagonist
Small molecule
Approved
CANCER; OTHER
INJECTION; INTRAVENOUS; IV (INFUSION)
Glioma; Chordoma; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Meningeal Carcinomatosis; Thymoma; Thymus Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Liver Neoplasms; Medulloblastoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neuroendocrine Tumors; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Adenocarcinoma of Lung; Carcinoma; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Lung Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Mesothelioma; Neoplasms
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Unknown
Unknown
Small molecule
Approved
EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Essential Tremor; Marijuana Abuse; Tobacco Use Disorder; Carcinoma, Squamous Cell; Cough; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Alcoholism; Complex Regional Pain Syndromes; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Anxiety Disorders; Breast Neoplasms; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries
Voltage-gated calcium channel modulator
Small molecule
Approved
Unknown
Unknown
Urinary Bladder, Overactive; Polyuria; Urinary Incontinence
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Renal Insufficiency, Chronic; Cholangitis, Sclerosing; Neoplasms; Persian Gulf Syndrome; Alzheimer Disease; Anemia, Sickle Cell; Breast Neoplasms; Diverticulitis; Dyspepsia; Heart Failure, Systolic; Hepatitis C; HIV Infections; Intestinal Pseudo-Obstruction; Rosacea; Vaginosis, Bacterial; Brain Diseases; Clostridium Infections; Colitis, Collagenous; Crohn Disease; Helicobacter Infections; Hepatitis, Alcoholic; Irritable Bowel Syndrome; Liver Cirrhosis; Parkinson Disease; Peritonitis; Rectal Neoplasms; Diarrhea; Hepatic Encephalopathy; Infections
Bacterial DNA-directed RNA polymerase inhibitor
Small molecule
Approved
Unknown
Unknown
Urinary Bladder, Overactive; Polyuria; Urinary Incontinence
Unknown
Small molecule
Approved
CANCER
INJECTION; INTRAVENOUS
Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Lymphoma, T-Cell; Graft vs Host Disease; Hematologic Diseases; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Osteopetrosis; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA inhibitor
Small molecule
Approved
OTHER
INHALATION
Asthma; Humeral Fractures; Myocardial Infarction; Heart Arrest; Lung Neoplasms; Multiple Organ Failure; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Scleroderma, Systemic; Raynaud Disease; Respiratory Distress Syndrome; Shock, Septic; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis
Prostanoid IP receptor agonist
Small molecule
Approved
OTHER
ORAL
Scleroderma, Systemic; Crohn Disease; Dry Eye Syndromes; Leukemia, Myeloid, Acute; Renal Insufficiency, Chronic; Diabetes Mellitus, Type 1; Graft vs Host Disease; Lupus Erythematosus, Systemic; Lupus Nephritis; Nephrotic Syndrome; Uveitis, Intermediate; Immune System Diseases
Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor
Small molecule
Approved
Unknown
Unknown
Stress Disorders, Post-Traumatic; Stroke; Amphetamine-Related Disorders; Alcoholism; Attention Deficit Disorder with Hyperactivity; Colorectal Neoplasms; Diabetes Mellitus; Diabetic Nephropathies; Fatigue Syndrome, Chronic; Multiple Sclerosis; Myalgia; Neuralgia; Pain; Peripheral Nervous System Diseases; Anxiety; Anxiety Disorders; Back Pain; Biliary Dyskinesia; Dementia; Depressive Disorder, Major; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Osteoarthritis; Osteoarthritis, Knee; Parkinson Disease; Schizophrenia; Shoulder Pain; Urinary Incontinence; Depressive Disorder
Unknown
Small molecule
Approved
Unknown
Unknown
Carcinoma, Squamous Cell; Cheilitis; Uterine Cervical Dysplasia; Acne Vulgaris; Carcinoma, Basal Cell; Keratosis, Actinic; Skin Aging; Neoplasms
Unknown
Small molecule
Approved
OTHER
INTRAVENOUS
Unknown
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Pharyngeal Neoplasms; Adenocarcinoma of Lung; Astrocytoma; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colonic Neoplasms; Glioblastoma; Glioma; Hemorrhagic Fever, Ebola; Hepatitis C, Chronic; Kidney Neoplasms; Melanoma; Multiple Myeloma; Oligodendroglioma; Rectal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenomatous Polyposis Coli; Biliary Tract Neoplasms; Breast Neoplasms; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Lung Neoplasms; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Skin Neoplasms; Thymoma; Urinary Bladder Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Mouth Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Brain Neoplasms; Lymphoma
Unknown
Small molecule
Approved
Unknown
Unknown
Constipation
Unknown
Small molecule
Approved
Unknown
Unknown
Eczema; Carcinoma, Pancreatic Ductal; Crohn Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Propionic Acidemia; Renal Insufficiency, Chronic; Anxiety Disorders; Breast Neoplasms; Clostridium Infections; Cystic Fibrosis; Heart Failure; Infections; Irritable Bowel Syndrome; Lymphoma; Multiple Myeloma; Periodontitis; Prostatic Neoplasms, Castration-Resistant; Thalassemia; Wounds and Injuries; Colorectal Neoplasms; Coronary Disease; Diarrhea; Fetal Growth Retardation; Malnutrition; Mucositis; Multiple Organ Failure; Muscular Dystrophy, Duchenne; Neoplasms; Peripheral Nervous System Diseases; Premature Birth; Sepsis; Severe Acute Respiratory Syndrome; Stomatitis; Anemia, Sickle Cell; Short Bowel Syndrome
Unknown
Small molecule
Approved
Unknown
Unknown
Atrophy; Menopause
Estrogen receptor agonist
Small molecule
Approved
Unknown
Unknown
Rickets, Hypophosphatemic; Chronic Kidney Disease-Mineral and Bone Disorder; Hyperparathyroidism, Primary; Memory Disorders; Hyperparathyroidism; Hyperparathyroidism, Secondary; Renal Insufficiency, Chronic; Parathyroid Diseases
Unknown
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Pulmonary Disease, Chronic Obstructive; Schizophrenia; Urinary Bladder, Overactive; Urinary Incontinence, Urge
Muscarinic acetylcholine receptor M2 antagonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Asthma; Maxillary Sinusitis; Otitis Media; Otitis Media, Suppurative; Pharyngitis; Scrub Typhus; Tonsillitis; Bacterial Infections; Infections; Pneumonia
Bacterial 70S ribosome inhibitor
Small molecule
Unknown
Unknown
Unknown
Kidney Diseases; Hyperphosphatemia; Kidney Failure, Chronic; Renal Insufficiency, Chronic
Phosphate sequestering agent
Small molecule
Approved
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Malaria, Vivax; Urethritis; Candidiasis; Helicobacter Infections; Stomach Neoplasms; Amebiasis; Bacterial Infections; Trichomonas Infections; Vaginal Diseases; Vaginosis, Bacterial
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Chagas Cardiomyopathy; Metabolic Syndrome; Breast Carcinoma In Situ; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Fatty Liver; Lymphoma, Non-Hodgkin; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Wounds and Injuries; Aggression; Autistic Disorder; Bipolar Disorder; Breast Neoplasms; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depression, Postpartum; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Dysthymic Disorder; Epilepsy; Glomerulonephritis, IGA; Inflammation; Lichen Planus, Oral; Myositis; Oral Ulcer; Periodontitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychotic Disorders; Renal Insufficiency, Chronic; Sarcopenia; Schizophrenia; Acne Vulgaris; Alzheimer Disease; Atrial Fibrillation; Attention Deficit Disorder with Hyperactivity; Dry Eye Syndromes; Heart Diseases; Heart Failure; HIV Infections; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypertension; Hypertriglyceridemia; Insulin Resistance; Intermittent Claudication; Language Disorders; Lipid Metabolism Disorders; Myocardial Infarction; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Peripheral Arterial Disease; Pyelonephritis; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypothyroidism
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Marijuana Abuse; Burns; Migraine with Aura; Migraine without Aura; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Sleep Wake Disorders; Substance-Related Disorders; Tobacco Use Disorder; Bipolar Disorder; Depressive Disorder; Sleep Initiation and Maintenance Disorders
Melatonin receptor agonist
Small molecule
Approved
DERMATOLOGY
INTRAVENOUS
Leukemia, Myeloid, Acute; Liver Cirrhosis, Biliary; Renal Insufficiency, Chronic; Bacteremia; Abdominal Abscess; Diabetic Foot; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Osteomyelitis; Pneumonia, Bacterial; Skin Diseases; Staphylococcal Infections; Bacterial Infections; Infections; Intraabdominal Infections
Bacterial 70S ribosome inhibitor
Small molecule
Approved
OTHER
ORAL
Liver Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Anemia; Hemochromatosis; Leukemia, Myeloid, Acute; Mucormycosis; Osteoporosis, Postmenopausal; Anemia, Sickle Cell; beta-Thalassemia; Hemosiderosis; Porphyria Cutanea Tarda; Red-Cell Aplasia, Pure; Thalassemia; Myelodysplastic Syndromes
Iron chelating agent
Small molecule
Approved
CANCER
INTRAVENOUS
Leukemia, Lymphoid; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Leukemia; Leukemia, Biphenotypic, Acute; Lymphoma; Mycosis Fungoides; Sezary Syndrome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia-Lymphoma, Adult T-Cell; Neoplasms
DNA inhibitor
Small molecule
Approved
CANCER; HEMATOLOGY; OTHER
ORAL
Astrocytoma; Burkitt Lymphoma; Cachexia; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colonic Neoplasms; Diffuse Intrinsic Pontine Glioma; Fallopian Tube Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, B-Cell; Neoplasms; Neuroblastoma; Ovarian Neoplasms; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma, Kaposi; Urethral Neoplasms; Amyloidosis; Autistic Disorder; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Complex Regional Pain Syndromes; Crohn Disease; Glioma; Gliosarcoma; Graft vs Host Disease; Hematologic Diseases; Hematologic Neoplasms; Histiocytosis, Sinus; HIV Infections; Hodgkin Disease; Kidney Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Plasma Cell; Leukemia, Prolymphocytic; Liver Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Myeloproliferative Disorders; Pancreatic Neoplasms; POEMS Syndrome; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Radiculopathy; Thrombocythemia, Essential; Thyroid Neoplasms; Urinary Bladder Neoplasms; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Epstein-Barr Virus Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Plasmacytoma; Prostatic Neoplasms, Castration-Resistant; Smoldering Multiple Myeloma; Anemia; Immune System Diseases; Lymphoma, Mantle-Cell; Multiple Myeloma; Myelodysplastic Syndromes
CRL4(CRBN) E3 ubiquitin ligase inhibitor
Small molecule
Approved
Unknown
Unknown
Chronic Pain; Malaria, Falciparum; Malaria
Unknown
Small molecule
Approved
Unknown
Unknown
Osteoarthritis; Carpal Tunnel Syndrome; Myofascial Pain Syndromes; Neuralgia, Postherpetic; Shoulder Impingement Syndrome; Skin Diseases; Tendinopathy; Wounds and Injuries; Cataract; Hemorrhoids; Pain; Pruritus
Sodium channel alpha subunit blocker
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Colorectal Neoplasms; Hepatitis C, Chronic; Hepatitis D; Liver Failure; Liver Neoplasms; Stomach Neoplasms; Carcinoma, Hepatocellular; Hepatitis B; Hepatitis B, Chronic; Liver Diseases; Virus Diseases
DNA polymerase/reverse transcriptase inhibitor