DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved GASTROINTESTINAL; OTHER; UROLOGY AND KIDNEY ORAL Bone Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Rhabdomyosarcoma; Small Cell Lung Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Cholangiocarcinoma; Digestive System Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Hemangiosarcoma; Liposarcoma; Macular Degeneration; Melanoma; Meningioma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neoplasms Discoidin domain-containing receptor 2 inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER; UROLOGY AND KIDNEY

ORAL

Bone Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Rhabdomyosarcoma; Small Cell Lung Carcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Cholangiocarcinoma; Digestive System Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Hemangiosarcoma; Liposarcoma; Macular Degeneration; Melanoma; Meningioma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neoplasms

Discoidin domain-containing receptor 2 inhibitor


Small molecule Approved EYE OPHTHALMIC Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension Prostanoid FP receptor agonist


Small molecule Approved Unknown Unknown Blood Coagulation Disorders; Ischemic Stroke; Nephrotic Syndrome; Thromboembolism; Foramen Ovale, Patent; Heart Failure; Hemorrhage; Liver Cirrhosis; Renal Insufficiency, Chronic; Acute Coronary Syndrome; Anemia, Sickle Cell; Aortic Valve Stenosis; Atrial Flutter; Hematoma; Ischemia; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Severe Acute Respiratory Syndrome; Arthroplasty; Atrial Fibrillation; Embolism; Pulmonary Embolism; Stroke; Thrombosis; Venous Thromboembolism; Venous Thrombosis Coagulation factor X inhibitor

Small molecule

Approved

Unknown

Blood Coagulation Disorders; Ischemic Stroke; Nephrotic Syndrome; Thromboembolism; Foramen Ovale, Patent; Heart Failure; Hemorrhage; Liver Cirrhosis; Renal Insufficiency, Chronic; Acute Coronary Syndrome; Anemia, Sickle Cell; Aortic Valve Stenosis; Atrial Flutter; Hematoma; Ischemia; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency; Severe Acute Respiratory Syndrome; Arthroplasty; Atrial Fibrillation; Embolism; Pulmonary Embolism; Stroke; Thrombosis; Venous Thromboembolism; Venous Thrombosis

Coagulation factor X inhibitor


Small molecule Approved Unknown Unknown Multiple Sclerosis; Glioblastoma; Alzheimer Disease; Cognitive Dysfunction; Radionuclide Imaging Diagnostic agent


Small molecule Approved Unknown Unknown Carcinoma, Squamous Cell; Gliosarcoma; Leukemia, Myeloid, Acute; Liver Diseases; Multiple Myeloma; Urogenital Neoplasms; Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Astrocytoma; Bile Duct Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Neuroendocrine; Cholangiocarcinoma; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Glioblastoma; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Melanoma; Meningioma; Neuroendocrine Tumors; Osteosarcoma; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Thyroid Neoplasms; Neoplasms Unknown

Small molecule

Approved

Unknown

Carcinoma, Squamous Cell; Gliosarcoma; Leukemia, Myeloid, Acute; Liver Diseases; Multiple Myeloma; Urogenital Neoplasms; Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Astrocytoma; Bile Duct Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Neuroendocrine; Cholangiocarcinoma; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Glioblastoma; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Melanoma; Meningioma; Neuroendocrine Tumors; Osteosarcoma; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Thyroid Neoplasms; Neoplasms

Unknown


Small molecule Approved RESPIRATORY ORAL Tuberculosis; Tuberculosis, Multidrug-Resistant ATP synthase inhibitor


Small molecule Approved Unknown Unknown Neoplasms; Erdheim-Chester Disease; Multiple Myeloma; Glioblastoma; Glioma; Lung Neoplasms; Melanoma Dual specificity mitogen-activated protein kinase kinase 1 inhibitor


Small molecule Approved Unknown Unknown Dermatitis; Diabetes Mellitus, Type 2; Heart Diseases; Periodontitis; Dry Eye Syndromes; Low Back Pain; Lupus Erythematosus, Systemic; Neonatal Sepsis; Obesity; Osteoarthritis, Knee; Periodontal Diseases; Psoriasis; Sarcopenia; Hypertriglyceridemia Unknown


Small molecule Approved Unknown Unknown Diabetes Mellitus; Diabetes Mellitus, Type 2 Unknown


Small molecule Approved PREGNANCY AND GYNECOLOGY ORAL Paget Disease, Extramammary; Atrophic Vaginitis; Atrophy; Dyspareunia; Menopause Estrogen receptor modulator


Small molecule Approved HEMATOLOGY ORAL Breast Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Glioblastoma; Liver Diseases; Lung Neoplasms; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Amyloidosis; Anaphylaxis; Anemia, Hemolytic, Autoimmune; Burkitt Lymphoma; Carcinoid Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Esophageal Neoplasms; Food Hypersensitivity; Head and Neck Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic; Leukemia, Prolymphocytic, T-Cell; Mastocytosis, Systemic; Melanoma; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Bronchiolitis Obliterans Syndrome; Graft vs Host Disease; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Neoplasms; Waldenstrom Macroglobulinemia Tyrosine-protein kinase BTK inhibitor

Small molecule

Approved

HEMATOLOGY

ORAL

Breast Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Glioblastoma; Liver Diseases; Lung Neoplasms; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Amyloidosis; Anaphylaxis; Anemia, Hemolytic, Autoimmune; Burkitt Lymphoma; Carcinoid Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Esophageal Neoplasms; Food Hypersensitivity; Head and Neck Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Lymphoid; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Leukemia, Prolymphocytic; Leukemia, Prolymphocytic, T-Cell; Mastocytosis, Systemic; Melanoma; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Bronchiolitis Obliterans Syndrome; Graft vs Host Disease; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Neoplasms; Waldenstrom Macroglobulinemia

Tyrosine-protein kinase BTK inhibitor


Small molecule Approved Unknown ORAL Amyotrophic Lateral Sclerosis; Malaria; Weight Gain; Acquired Immunodeficiency Syndrome; HIV Infections; Infections; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Asthma; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive Beta-2 adrenergic receptor agonist


Small molecule Approved CANCER; HEMATOLOGY; OTHER ORAL Anemia, Sickle Cell; Burkitt Lymphoma; Castleman Disease; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Waldenstrom Macroglobulinemia; Amyloidosis; Amyloidosis, Familial; Central Nervous System Neoplasms; Graft vs Host Disease; Leukemia, Plasma Cell; Lung Diseases, Interstitial; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Plasmacytoma; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Pulmonary Fibrosis; Sarcoma; Sarcoma, Kaposi; Scleroderma, Systemic; Smoldering Multiple Myeloma; Telangiectasia, Hereditary Hemorrhagic; Primary Myelofibrosis; Immune System Diseases; Multiple Myeloma CRL4(CRBN) E3 ubiquitin ligase inhibitor

Small molecule

Approved

CANCER; HEMATOLOGY; OTHER

ORAL

Anemia, Sickle Cell; Burkitt Lymphoma; Castleman Disease; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Waldenstrom Macroglobulinemia; Amyloidosis; Amyloidosis, Familial; Central Nervous System Neoplasms; Graft vs Host Disease; Leukemia, Plasma Cell; Lung Diseases, Interstitial; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Plasmacytoma; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Pulmonary Fibrosis; Sarcoma; Sarcoma, Kaposi; Scleroderma, Systemic; Smoldering Multiple Myeloma; Telangiectasia, Hereditary Hemorrhagic; Primary Myelofibrosis; Immune System Diseases; Multiple Myeloma

CRL4(CRBN) E3 ubiquitin ligase inhibitor


Small molecule Approved Unknown ORAL Liver Diseases; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Feeding and Eating Disorders; Anxiety Disorders; Depressive Disorder; Depressive Disorder, Major Unknown


Small molecule Approved Unknown Unknown Asthma; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved OTHER ORAL Hepatitis B, Chronic; Lymphoma; Infections; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; Virus Diseases RNA-directed RNA polymerase inhibitor


Small molecule Approved DERMATOLOGY TOPICAL Onychomycosis; Tinea; Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved OTHER INTRAVENOUS Lung Diseases, Interstitial; Brain Neoplasms; Central Nervous System Diseases Diagnostic agent


Small molecule Approved Unknown Unknown Brain Neoplasms; Cholangiocarcinoma; Endometriosis; Glioblastoma; Liver Diseases; Neoplasm Metastasis; Pancreatic Neoplasms; Renal Insufficiency; Stomach Neoplasms; Chordoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Lung Neoplasms; Multiple Myeloma; Paraganglioma; Prostatic Neoplasms; Small Cell Lung Carcinoma; Urogenital Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Neoplasms Unknown

Small molecule

Approved

Unknown

Brain Neoplasms; Cholangiocarcinoma; Endometriosis; Glioblastoma; Liver Diseases; Neoplasm Metastasis; Pancreatic Neoplasms; Renal Insufficiency; Stomach Neoplasms; Chordoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Lung Neoplasms; Multiple Myeloma; Paraganglioma; Prostatic Neoplasms; Small Cell Lung Carcinoma; Urogenital Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Neoplasms

Unknown


Small molecule Approved Unknown Unknown Brain Neoplasms; Glioma; Kidney Diseases; Liver Diseases; Multiple Myeloma; Adenocarcinoma, Follicular; Carcinoma; Carcinoma, Non-Small-Cell Lung; Craniopharyngioma; Erdheim-Chester Disease; Lung Neoplasms; Thyroid Carcinoma, Anaplastic; Ameloblastoma; Melanoma; Thyroid Neoplasms; Neoplasms Unknown


Small molecule Approved CANCER; OTHER ORAL Multiple Myeloma; Carcinoma, Non-Small-Cell Lung Epidermal growth factor receptor erbB1 inhibitor


Small molecule Approved OTHER ORAL Depressive Disorder, Major Norepinephrine transporter inhibitor


Small molecule Approved Unknown Unknown Sarcoma; Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant Unknown


Small molecule Approved Unknown Unknown Cardiomyopathies; Alzheimer Disease; Cognitive Dysfunction; Radionuclide Imaging Diagnostic agent


Small molecule Approved Unknown Unknown Breast Neoplasms; Gastroparesis; Hypospadias; Kidney Diseases; Obesity, Morbid; Pain; Postoperative Complications; Burns; Headache; Postoperative Nausea and Vomiting; Glaucoma Unknown

Small molecule

Approved

IMMUNE SYSTEM; MUSCULOSKELETAL; OTHER

ORAL

Gliosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cerebral Hemorrhage; Ischemic Stroke; Lymphoma, T-Cell, Cutaneous; Sleep Apnea, Obstructive; Multiple Sclerosis, Chronic Progressive; Severe Acute Respiratory Syndrome; Immune System Diseases; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Psoriasis

Kelch-like ECH-associated protein 1 inhibitor


Small molecule Approved CARDIOVASCULAR; OTHER; RESPIRATORY ORAL HIV Infections; Anemia, Sickle Cell; Coronary Disease; Cystic Fibrosis; Ischemic Stroke; Raynaud Disease; Scleroderma, Localized; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary Soluble guanylate cyclase positive allosteric modulator


Small molecule Approved Unknown Unknown Alzheimer Disease; Breast Neoplasms Unknown


Small molecule Approved Unknown Unknown Tobacco Use Disorder; Depressive Disorder Unknown


Small molecule Approved Unknown Unknown Renal Insufficiency, Chronic; Hepatitis C; Hepatitis C, Chronic; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Asthma; Hyperhidrosis; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved DERMATOLOGY TOPICAL Onychomycosis Leucine-tRNA ligase inhibitor


Small molecule Approved OTHER ORAL Renal Insufficiency, Chronic; Anemia; Hyperphosphatemia Phosphate sequestering agent


Small molecule Approved EYE ORAL Kidney Diseases; Liver Diseases; REM Sleep Behavior Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders; Sleep Disorders, Circadian Rhythm; Sleep Wake Disorders; Smith-Magenis Syndrome Melatonin receptor agonist