Display Options:
Total: 6532
Small molecule
Unknown
Unknown
Unknown
Atypical Hemolytic Uremic Syndrome; Glomerulonephritis, IGA; Hidradenitis Suppurativa; Vasculitis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Granulomatosis with Polyangiitis; Microscopic Polyangiitis
C5a anaphylatoxin chemotactic receptor antagonist
Small molecule
Approved
Unknown
Unknown
Depressive Disorder
Unknown
Small molecule
Unknown
Unknown
Unknown
Mycoses; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Blastomycosis; Candidemia; Candidiasis, Invasive; Candidiasis, Vulvovaginal; Coccidioidomycosis; Histoplasmosis; Vulvovaginitis
1,3-beta-glucan synthase inhibitor
Small molecule
approved
Unknown
Unknown
Cytomegalovirus Infections; Virus Diseases
Phosphotransferase pUL97 inhibitor
Small molecule
Unknown
Unknown
Unknown
Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Diagnostic agent
Small molecule
Unknown
Unknown
Unknown
Liver Diseases; Neoplasms; Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung
GTPase KRas inhibitor
Small molecule
Unknown
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Norepinephrine transporter inhibitor
Small molecule
Approved
Unknown
Unknown
Coronary Disease; Cardiovascular Diseases; Heart Failure
Soluble guanylate cyclase activator
Small molecule
Unknown
Unknown
Unknown
Breast Neoplasms; Prostatic Neoplasms; Severe Acute Respiratory Syndrome; Menopause; Pregnancy
Estrogen receptor agonist
Small molecule
Approved
Unknown
Unknown
Multiple Myeloma
Unknown
Small molecule
Approved
Unknown
Unknown
Graft vs Host Disease; Psoriasis; Multiple Sclerosis
Sphingosine 1-phosphate receptor Edg-1 agonist
Small molecule
Approved
Unknown
Unknown
Chagas Disease; Infections; Leishmaniasis, Visceral; Leishmaniasis; Trypanosomiasis; Trypanosomiasis, African
Cytotoxic
Small molecule
Unknown
Unknown
Unknown
Graft vs Host Disease
Rho-associated protein kinase inhibitor
Small molecule
Unknown
Unknown
Unknown
Kidney Diseases; Liver Diseases; Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Unknown
Unknown
Unknown
Metal Metabolism, Inborn Errors
Unknown
Small molecule
Unknown
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Ovarian Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Carcinoma, Hepatocellular; Liver Diseases; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Neoplasms
Hepatocyte growth factor receptor inhibitor
Small molecule
Approved
Unknown
Unknown
Migraine Disorders
Calcitonin gene-related peptide type 1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Carcinoma, Renal Cell; Hemangioblastoma; Neuroendocrine Tumors; von Hippel-Lindau Disease
Endothelial PAS domain-containing protein 1 inhibitor
Small molecule
Approved
Unknown
Unknown
Heart Failure; Cardiomyopathy, Hypertrophic
Unknown
Small molecule
Approved
Unknown
Unknown
Dermatitis, Atopic; Psoriasis
Aryl hydrocarbon receptor agonist
Small molecule
Small molecule
Unknown
Unknown
Leukemia, Myeloid, Acute; Myelodysplastic Syndromes
Isocitrate dehydrogenase [NADP] cytoplasmic inhibitor
Small molecule
Approved
Unknown
Unknown
Epilepsies, Partial; Epilepsy; Epilepsy, Complex Partial; Fragile X Syndrome; Smoking Cessation; Spasms, Infantile; Stress Disorders, Post-Traumatic; Tuberous Sclerosis; Seizures; Status Epilepticus
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
Unknown
Unknown
Tinea Pedis; Candidiasis, Vulvovaginal
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Psoriasis; Dermatitis, Atopic
Tyrosine-protein kinase JAK1 inhibitor
Small molecule
Approved
Unknown
Unknown
Immune System Diseases; Kidney Diseases; Liver Diseases; Colitis, Ulcerative; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Lupus Nephritis; Arthritis, Psoriatic; Psoriasis
Tyrosine-protein kinase TYK2 negative allosteric modulator
Small molecule
Unknown
Unknown
Unknown
Liver Diseases; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders
Orexin receptor antagonist
Small molecule
Approved
Unknown
Unknown
Anemia, Sickle Cell; Thalassemia; Anemia
Unknown
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Breast Neoplasms; Carcinoma, Hepatocellular; Neoplasms; Cholangiocarcinoma; Sarcoma
Fibroblast growth factor receptor inhibitor
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Graft vs Host Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Colorectal Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Myeloproliferative Disorders; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome
Tyrosine-protein kinase JAK2 inhibitor
Small molecule
Approved
Unknown
Unknown
HIV Infections
Structural capsid protein inhibitor
Small molecule
Approved
Unknown
Unknown
Cocaine-Related Disorders; Depressive Disorder
Unknown
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Heart Failure; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes Mellitus
Sodium/glucose cotransporter 1 inhibitor