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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
Small Molecules
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
6532
BIIF 1149 BS
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BIIF 1149 BS
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NNZ-2591
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NNZ-2591
×
Maximum Phase:
1
First Approval:
None
UNII:
2T1HU6069S
Molecule Type:
Small molecule
Molecular Formula:
C10H14N2O2
Molecular Weight:
194.23
AlogP:
0.05
PSA:
49.41
HBD:
1.0
HBA:
#RotB:
2.0
Source:
AZD3514
1
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Androgen Receptor modulator
AZD3514
×
Maximum Phase:
1
First Approval:
None
UNII:
127DSS8X7J
Molecule Type:
Small molecule
Molecular Formula:
C25H32F3N7O2
Molecular Weight:
519.57
AlogP:
2.83
PSA:
79.09
HBD:
0.0
HBA:
#RotB:
5.0
Source:
BMS-779788
1
Small molecule
Investigational
Unknown
Unknown
Atherosclerosis
LXR-beta agonist
BMS-779788
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DANAVOREXTON
1
Small molecule
Investigational
Unknown
Unknown
Idiopathic Hypersomnia; Narcolepsy; Sleep Apnea, Obstructive
Unknown
DANAVOREXTON
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C21H32N2O5S
Molecular Weight:
424.56
AlogP:
2.88
PSA:
84.94
HBD:
1.0
HBA:
#RotB:
6.0
Source:
RWJ-67657
1
Small molecule
Investigational
Unknown
Unknown
Unknown
MAP kinase p38 alpha inhibitor
RWJ-67657
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C27H24FN3O
Molecular Weight:
425.51
AlogP:
5.12
PSA:
50.94
HBD:
1.0
HBA:
#RotB:
7.0
Source:
GET-73
1
Small molecule
Investigational
Unknown
Unknown
Alcoholism
Unknown
GET-73
×
Maximum Phase:
1
First Approval:
None
UNII:
U5CLZ223FH
Molecule Type:
Small molecule
Molecular Formula:
C13H16F3NO2
Molecular Weight:
275.27
AlogP:
2.75
PSA:
38.33
HBD:
1.0
HBA:
#RotB:
6.0
Source:
OBP-801
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
OBP-801
×
Maximum Phase:
1
First Approval:
None
UNII:
30Q3VS5HZ4
Molecule Type:
Small molecule
Molecular Formula:
C20H31N3O6S2
Molecular Weight:
473.62
AlogP:
0.52
PSA:
133.83
HBD:
4.0
HBA:
#RotB:
1.0
Source:
AN-2718
1
Small molecule
Investigational
Unknown
Unknown
Tinea Pedis
Unknown
AN-2718
×
Maximum Phase:
1
First Approval:
None
UNII:
810U6C2DGG
Molecule Type:
Small molecule
Molecular Formula:
C7H6BClO2
Molecular Weight:
168.39
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
MURIZATOCLAX
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes
Unknown
MURIZATOCLAX
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C42H57ClN4O5S
Molecular Weight:
765.46
AlogP:
6.44
PSA:
91.42
HBD:
1.0
HBA:
#RotB:
3.0
Source:
GSK-424887
1
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder
Unknown
GSK-424887
×
Maximum Phase:
1
First Approval:
None
UNII:
IYI99KCF2T
Molecule Type:
Small molecule
Molecular Formula:
C27H30ClFN2O
Molecular Weight:
453.0
AlogP:
6.21
PSA:
23.55
HBD:
0.0
HBA:
#RotB:
5.0
Source:
ON123300
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
ON123300
×
Maximum Phase:
1
First Approval:
None
UNII:
QJ8RO3296G
Molecule Type:
Small molecule
Molecular Formula:
C24H27N7O
Molecular Weight:
429.53
AlogP:
3.27
PSA:
90.08
HBD:
1.0
HBA:
#RotB:
4.0
Source:
TAFETINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
TAFETINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
H4X2M2NN5N
Molecule Type:
Small molecule
Molecular Formula:
C24H29FN4O2
Molecular Weight:
424.52
AlogP:
3.73
PSA:
77.23
HBD:
3.0
HBA:
#RotB:
6.0
Source:
POLYGLYCONATE
1
Small molecule
Investigational
Unknown
Unknown
Influenza, Human
Unknown
POLYGLYCONATE
×
Maximum Phase:
1
First Approval:
None
UNII:
KOF6AD0GWS
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ASTODRIMER SODIUM
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ASTODRIMER SODIUM
×
Maximum Phase:
1
First Approval:
None
UNII:
8Q3B8SV59L
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
D-FLUOROMETHYLTYROSINE
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
D-FLUOROMETHYLTYROSINE
×
Maximum Phase:
1
First Approval:
None
UNII:
GSM7N3U4J8
Molecule Type:
Small molecule
Molecular Formula:
C10H12FNO3
Molecular Weight:
213.21
AlogP:
0.95
PSA:
72.55
HBD:
2.0
HBA:
#RotB:
5.0
Source:
MK-8245
1
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
MK-8245
×
Maximum Phase:
1
First Approval:
None
UNII:
537E7QE8LX
Molecule Type:
Small molecule
Molecular Formula:
C17H16BrFN6O4
Molecular Weight:
467.26
AlogP:
2.36
PSA:
119.4
HBD:
1.0
HBA:
#RotB:
6.0
Source:
AZD-4769
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Epidermal growth factor receptor erbB1 inhibitor
AZD-4769
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C28H27NO3S
Molecular Weight:
457.6
AlogP:
6.7
PSA:
59.42
HBD:
1.0
HBA:
#RotB:
11.0
Source:
TROTABRESIB
1
Small molecule
Investigational
Unknown
Unknown
Glioblastoma; Lymphoma, Non-Hodgkin
Unknown
TROTABRESIB
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C21H21NO4S
Molecular Weight:
383.47
AlogP:
3.4
PSA:
65.37
HBD:
0.0
HBA:
#RotB:
5.0
Source:
U-50488 METHANE SULFONATE
1
Small molecule
Investigational
Unknown
Unknown
Osteoarthritis
Unknown
U-50488 METHANE SULFONATE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C20H30Cl2N2O4S
Molecular Weight:
465.44
AlogP:
4.4
PSA:
23.55
HBD:
0.0
HBA:
#RotB:
4.0
Source:
BMS-908662
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BMS-908662
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CI-988
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Cholecystokinin B receptor antagonist
CI-988
×
Maximum Phase:
1
First Approval:
None
UNII:
2637PDX9SI
Molecule Type:
Small molecule
Molecular Formula:
C35H42N4O6
Molecular Weight:
614.74
AlogP:
4.86
PSA:
149.62
HBD:
5.0
HBA:
#RotB:
12.0
Source:
PF-04455242
1
Small molecule
Investigational
Unknown
Unknown
Bipolar Disorder; Depressive Disorder
Unknown
PF-04455242
×
Maximum Phase:
1
First Approval:
None
UNII:
Y3530Z78QD
Molecule Type:
Small molecule
Molecular Formula:
C21H28N2O2S
Molecular Weight:
372.53
AlogP:
3.88
PSA:
49.41
HBD:
1.0
HBA:
#RotB:
7.0
Source:
TC-2216
1
Small molecule
Investigational
Unknown
Unknown
Anxiety; Depressive Disorder
Neuronal acetylcholine receptor; alpha4/beta2 antagonist
TC-2216
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H17N3
Molecular Weight:
203.29
AlogP:
1.41
PSA:
28.16
HBD:
1.0
HBA:
#RotB:
1.0
Source:
NP-G2-044
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
NP-G2-044
×
Maximum Phase:
1
First Approval:
None
UNII:
1ER2O3UZ4W
Molecule Type:
Small molecule
Molecular Formula:
C21H16F3N3O2
Molecular Weight:
399.37
AlogP:
5.26
PSA:
60.06
HBD:
1.0
HBA:
#RotB:
4.0
Source:
CFG-920
1
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Unknown
CFG-920
×
Maximum Phase:
1
First Approval:
None
UNII:
UP0K5026VB
Molecule Type:
Small molecule
Molecular Formula:
C14H13ClN4O
Molecular Weight:
288.74
AlogP:
2.89
PSA:
49.33
HBD:
0.0
HBA:
#RotB:
2.0
Source:
AT-406
1
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Leukemia, Myeloid, Acute; Lymphoma; Neoplasms; Carcinoma, Squamous Cell
Unknown
AT-406
×
Maximum Phase:
1
First Approval:
None
UNII:
N65WC8PXDD
Molecule Type:
Small molecule
Molecular Formula:
C32H43N5O4
Molecular Weight:
561.73
AlogP:
2.62
PSA:
110.85
HBD:
3.0
HBA:
#RotB:
9.0
Source:
PF-06815345
1
Small molecule
Investigational
Unknown
Unknown
Hypercholesterolemia
Unknown
PF-06815345
×
Maximum Phase:
1
First Approval:
None
UNII:
4H9X9HO87K
Molecule Type:
Small molecule
Molecular Formula:
C27H29ClFN9O4
Molecular Weight:
598.04
AlogP:
4.02
PSA:
142.18
HBD:
1.0
HBA:
#RotB:
8.0
Source:
LBS-008
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
LBS-008
×
Maximum Phase:
1
First Approval:
None
UNII:
63WI9S8P1M
Molecule Type:
Small molecule
Molecular Formula:
C21H21F5N4O2
Molecular Weight:
456.42
AlogP:
3.63
PSA:
69.3
HBD:
1.0
HBA:
#RotB:
2.0
Source:
1,1'-METHYLENEBIS(4-((HYDROXYIMINO)METHYL)-PYRIDINIUM)
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
1,1'-METHYLENEBIS(4-((HYDROXYIMINO)METHYL)-PYRIDINIUM)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C13H14N4O2+2
Molecular Weight:
258.28
AlogP:
0.38
PSA:
72.94
HBD:
2.0
HBA:
#RotB:
4.0
Source:
VLX-1005
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VLX-1005
×
Maximum Phase:
1
First Approval:
None
UNII:
JKU4XCC48Y
Molecule Type:
Small molecule
Molecular Formula:
C21H19N3O4S2
Molecular Weight:
441.53
AlogP:
4.42
PSA:
100.55
HBD:
3.0
HBA:
#RotB:
7.0
Source:
PIMASERTIB HYDROCHLORIDE
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
PIMASERTIB HYDROCHLORIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
6GS1ULF5HV
Molecule Type:
Small molecule
Molecular Formula:
C15H16ClFIN3O3
Molecular Weight:
467.67
AlogP:
1.65
PSA:
94.48
HBD:
4.0
HBA:
#RotB:
6.0
Source:
MK-6186
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
MK-6186
×
Maximum Phase:
1
First Approval:
None
UNII:
K3978U665M
Molecule Type:
Small molecule
Molecular Formula:
C21H12Cl2N6O
Molecular Weight:
435.27
AlogP:
5.33
PSA:
92.41
HBD:
1.0
HBA:
#RotB:
4.0
Source:
DANICAMTIV
1
Small molecule
Investigational
Unknown
Unknown
Cardiomyopathy, Dilated
Cardiac myosin activator
DANICAMTIV
×
Maximum Phase:
1
First Approval:
None
UNII:
7B2CS922HI
Molecule Type:
Small molecule
Molecular Formula:
C16H20F3N5O4S
Molecular Weight:
435.43
AlogP:
2.75
PSA:
110.33
HBD:
1.0
HBA:
#RotB:
5.0
Source:
EMD-1204831
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Hepatocyte growth factor receptor inhibitor
EMD-1204831
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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76
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Compound Name
Maximum Phase
Compound Structure
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Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA