DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved OTHER ORAL Unknown Unknown


Small molecule Approved OTHER ORAL Alcoholism; Brain Injuries; Chondrocalcinosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Influenza in Birds; Kidney Diseases; Neoplasms; Cellulitis; Heart Failure; Heart Failure, Systolic; Cystitis, Hemorrhagic; Infections; Infertility, Male; Obesity; Urinary Tract Infections; Gout Solute carrier family 22 member 11 inhibitor


Small molecule Approved OTHER ORAL Amphetamine-Related Disorders; Fatigue; HIV Infections; Multiple Myeloma; Neoplasms; Obesity; Prostatic Neoplasms, Castration-Resistant; Retinal Dystrophies; Sarcoma; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Pancreatic Neoplasms; Paraganglioma; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations Aldehyde dehydrogenase inhibitor

Small molecule

Approved

OTHER

ORAL

Amphetamine-Related Disorders; Fatigue; HIV Infections; Multiple Myeloma; Neoplasms; Obesity; Prostatic Neoplasms, Castration-Resistant; Retinal Dystrophies; Sarcoma; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Pancreatic Neoplasms; Paraganglioma; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations

Aldehyde dehydrogenase inhibitor


Small molecule Approved OTHER TOPICAL Unknown Tyrosinase inhibitor


Small molecule Approved OTHER FOR RX COMPOUNDING; INJECTION; ORAL; RECTAL; TOPICAL; VAGINAL Diabetes Mellitus, Type 1; Fibromyalgia; HIV Infections; Infections; Insulin Resistance; Lymphoma, Large-Cell, Anaplastic; Obesity; Tobacco Use Disorder; Addison Disease; Adrenal Cortex Neoplasms; Aging; Atrial Fibrillation; Borderline Personality Disorder; Central Nervous System Neoplasms; Granuloma, Pyogenic; Heart Failure; Inflammatory Bowel Diseases; Leukemia, Mast-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Large B-Cell, Diffuse; Melanoma; Memory Disorders; Multiple Myeloma; Myocardial Infarction; Neoplasms, Plasma Cell; Opioid-Related Disorders; Pancreatitis; Phobic Disorders; Wounds and Injuries; Alcoholism; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Bronchopulmonary Dysplasia; Eczema; Heart Arrest; Hypotension; Hypoxia; Influenza, Human; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oral Submucous Fibrosis; Pain; Pneumonia, Viral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis; Dermatitis, Atopic; Dermatitis, Seborrheic; Endocrine System Diseases; Exanthema; Eye Diseases; Hemorrhoids; Herpes Labialis; Inflammation; Leukemia; Lymphoma; Nasal Obstruction; Neoplasms; Osteoarthritis; Otitis Externa; Pneumonia; Pruritus; Psoriasis; Serum Sickness; Skin Diseases; Spondylitis; Tenosynovitis Glucocorticoid receptor agonist

Small molecule

Approved

OTHER

FOR RX COMPOUNDING; INJECTION; ORAL; RECTAL; TOPICAL; VAGINAL

Diabetes Mellitus, Type 1; Fibromyalgia; HIV Infections; Infections; Insulin Resistance; Lymphoma, Large-Cell, Anaplastic; Obesity; Tobacco Use Disorder; Addison Disease; Adrenal Cortex Neoplasms; Aging; Atrial Fibrillation; Borderline Personality Disorder; Central Nervous System Neoplasms; Granuloma, Pyogenic; Heart Failure; Inflammatory Bowel Diseases; Leukemia, Mast-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Large B-Cell, Diffuse; Melanoma; Memory Disorders; Multiple Myeloma; Myocardial Infarction; Neoplasms, Plasma Cell; Opioid-Related Disorders; Pancreatitis; Phobic Disorders; Wounds and Injuries; Alcoholism; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Bronchopulmonary Dysplasia; Eczema; Heart Arrest; Hypotension; Hypoxia; Influenza, Human; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oral Submucous Fibrosis; Pain; Pneumonia, Viral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis; Dermatitis, Atopic; Dermatitis, Seborrheic; Endocrine System Diseases; Exanthema; Eye Diseases; Hemorrhoids; Herpes Labialis; Inflammation; Leukemia; Lymphoma; Nasal Obstruction; Neoplasms; Osteoarthritis; Otitis Externa; Pneumonia; Pruritus; Psoriasis; Serum Sickness; Skin Diseases; Spondylitis; Tenosynovitis

Glucocorticoid receptor agonist


Small molecule Approved OTHER INJECTION; ORAL Melanoma; Osteomyelitis; Acquired Immunodeficiency Syndrome; Diabetic Foot; Tuberculosis, Multidrug-Resistant; Ulcer; Meningitis; HIV Infections; Silicosis; Tuberculosis; Tuberculosis, Pulmonary Enoyl-[acyl-carrier-protein] reductase inhibitor


Small molecule Approved OTHER INJECTION; ORAL Osteomyelitis; Psoriasis; Rheumatic Heart Disease; HIV Infections; Syphilis; Bacterial Infections; Infections Bacterial penicillin-binding protein inhibitor


Unknown Approved OTHER INJECTION Adenocarcinoma, Follicular; Thyroid Neoplasms; Head and Neck Neoplasms Thyroid stimulating hormone receptor agonist


Small molecule Approved OTHER INJECTION; SUBCUTANEOUS Muscular Dystrophy, Facioscapulohumeral; HIV Wasting Syndrome; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Weight Loss; Hypogonadism; Neoplasms; Orchitis Androgen Receptor agonist


Small molecule Approved OTHER SUBCUTANEOUS Dermatitis; Fanconi Anemia; Gout; HIV Infections; Inflammation; Leukemia, Plasma Cell; Malaria; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Bone Marrow Failure Disorders; Burkitt Lymphoma; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Central Serous Chorioretinopathy; Colitis, Ulcerative; Colorectal Neoplasms; Constriction, Pathologic; Coronary Disease; Desmoid Tumors; Ependymoma; Hematologic Neoplasms; Hemoglobinuria; Histiocytosis, Langerhans-Cell; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelomonocytic, Juvenile; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Mesothelioma; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic-Myeloproliferative Diseases; Myocardial Infarction; Neoplasm Metastasis; Neoplasms, Plasma Cell; Neuroblastoma; Neurofibromatosis 1; Osteopetrosis; Ovarian Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Retinitis Pigmentosa; Schizophrenia; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Testicular Neoplasms; Urticaria; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Alopecia Areata; Anemia, Aplastic; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Asthma; Brain Neoplasms; Carcinoma, Squamous Cell; Cardiovascular Diseases; Central Nervous System Neoplasms; Choriocarcinoma; Choroid Plexus Neoplasms; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Gestational Trophoblastic Disease; Giant Cell Arteritis; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Hodgkin Disease; Hydatidiform Mole; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Cutaneous; Macular Edema; Medulloblastoma; Multiple Sclerosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive; Osteoarthritis; Osteosarcoma; Pemphigoid, Bullous; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy, Ectopic; Retroperitoneal Fibrosis; Sarcoma; Spondylitis, Ankylosing; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveitis; Uveitis, Intermediate; Vasculitis; Vitiligo; Vitreoretinopathy, Proliferative; Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Breast Neoplasms; Immune System Diseases; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Mycosis Fungoides; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psoriasis Dihydrofolate reductase inhibitor

Small molecule

Approved

OTHER

SUBCUTANEOUS

Dermatitis; Fanconi Anemia; Gout; HIV Infections; Inflammation; Leukemia, Plasma Cell; Malaria; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Bone Marrow Failure Disorders; Burkitt Lymphoma; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Central Serous Chorioretinopathy; Colitis, Ulcerative; Colorectal Neoplasms; Constriction, Pathologic; Coronary Disease; Desmoid Tumors; Ependymoma; Hematologic Neoplasms; Hemoglobinuria; Histiocytosis, Langerhans-Cell; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelomonocytic, Juvenile; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Mesothelioma; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic-Myeloproliferative Diseases; Myocardial Infarction; Neoplasm Metastasis; Neoplasms, Plasma Cell; Neuroblastoma; Neurofibromatosis 1; Osteopetrosis; Ovarian Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Retinitis Pigmentosa; Schizophrenia; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Testicular Neoplasms; Urticaria; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Alopecia Areata; Anemia, Aplastic; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Asthma; Brain Neoplasms; Carcinoma, Squamous Cell; Cardiovascular Diseases; Central Nervous System Neoplasms; Choriocarcinoma; Choroid Plexus Neoplasms; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Gestational Trophoblastic Disease; Giant Cell Arteritis; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Hodgkin Disease; Hydatidiform Mole; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Cutaneous; Macular Edema; Medulloblastoma; Multiple Sclerosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive; Osteoarthritis; Osteosarcoma; Pemphigoid, Bullous; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy, Ectopic; Retroperitoneal Fibrosis; Sarcoma; Spondylitis, Ankylosing; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveitis; Uveitis, Intermediate; Vasculitis; Vitiligo; Vitreoretinopathy, Proliferative; Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Breast Neoplasms; Immune System Diseases; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Mycosis Fungoides; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psoriasis

Dihydrofolate reductase inhibitor


Small molecule Approved OTHER INJECTION; ORAL Urinary Bladder, Overactive; Peptic Ulcer Muscarinic acetylcholine receptor M1 antagonist


Small molecule Approved OTHER ORAL Burkitt Lymphoma; Astrocytoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphoid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma Amidophosphoribosyltransferase inhibitor

Small molecule

Approved

OTHER

ORAL

Burkitt Lymphoma; Astrocytoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphoid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma

Amidophosphoribosyltransferase inhibitor


Small molecule Approved OTHER ORAL Osteomyelitis; Bacterial Infections; Cystitis; Urinary Tract Infections DNA inhibitor


Small molecule Approved OTHER ORAL Andersen Syndrome; Diabetes Mellitus, Type 1; Hypotension, Orthostatic; Melanoma; Prostatic Neoplasms, Castration-Resistant; Psychotic Disorders; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Retinoschisis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures Carbonic anhydrase II inhibitor

Small molecule

Approved

OTHER

ORAL

Andersen Syndrome; Diabetes Mellitus, Type 1; Hypotension, Orthostatic; Melanoma; Prostatic Neoplasms, Castration-Resistant; Psychotic Disorders; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Retinoschisis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures

Carbonic anhydrase II inhibitor


Small molecule Approved OTHER ORAL Unknown Bacterial dihydropteroate synthase inhibitor


Small molecule Approved OTHER ORAL Amyotrophic Lateral Sclerosis; Gangliosidoses, GM2; Head and Neck Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Sandhoff Disease; Tay-Sachs Disease; Toxoplasmosis, Cerebral; Anemia; Chorioretinitis; Depressive Disorder; HIV Infections; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth; Schistosomiasis; Schizophrenia; Toxoplasmosis, Congenital; Malaria; Toxoplasmosis Dihydrofolate reductase inhibitor

Small molecule

Approved

OTHER

ORAL

Amyotrophic Lateral Sclerosis; Gangliosidoses, GM2; Head and Neck Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Sandhoff Disease; Tay-Sachs Disease; Toxoplasmosis, Cerebral; Anemia; Chorioretinitis; Depressive Disorder; HIV Infections; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth; Schistosomiasis; Schizophrenia; Toxoplasmosis, Congenital; Malaria; Toxoplasmosis

Dihydrofolate reductase inhibitor


Small molecule Approved OTHER ORAL; SUBLINGUAL Dementia, Vascular; Fragile X Syndrome; Cardiovascular Diseases Adrenergic receptor alpha antagonist


Small molecule Approved OTHER ORAL Osteomyelitis; Bacterial Infections; Eye Infections Bacterial dihydropteroate synthase inhibitor


Small molecule Approved OTHER ORAL Unknown Muscarinic acetylcholine receptor M1 antagonist


Small molecule Approved OTHER ORAL Anemia; Cocaine-Related Disorders; Immune System Diseases; Leukemia; Lymphoma; Neuroblastoma; Anemia, Sickle Cell; Optic Neuritis; Pancreatic Neoplasms; Polyneuropathies; Thalassemia; Wounds and Injuries; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Epilepsy; Seizures Sodium channel alpha subunit blocker


Small molecule Approved OTHER INJECTION Unknown DNA inhibitor


Small molecule Approved CANCER; OTHER INJECTION; ORAL; TOPICAL Hematologic Neoplasms; Arthritis, Rheumatoid; Bronchiolitis Obliterans Syndrome; Crohn Disease; Epidermolysis Bullosa Acquisita; Pancreatic Neoplasms; Scleroderma, Diffuse; Sezary Syndrome; Graft vs Host Disease; Lymphoma; Mycosis Fungoides; Lymphoma, T-Cell; Psoriasis DNA inhibitor


Small molecule Approved OTHER ORAL Stroke; Epilepsy; Seizures GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER INJECTION; ORAL Acquired Immunodeficiency Syndrome; Anemia; Blast Crisis; Brain Neoplasms; Chordoma; Genetic Diseases, Inborn; HIV Infections; Leukemia, Myeloid; Liver Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Osteogenesis Imperfecta; Ovarian Neoplasms; Retinoblastoma; Wiskott-Aldrich Syndrome; X-Linked Combined Immunodeficiency Diseases; Adrenoleukodystrophy; Anemia, Sickle Cell; beta-Thalassemia; Breast Neoplasms, Male; Central Nervous System Neoplasms; Epidermolysis Bullosa; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immune System Diseases; Immunologic Deficiency Syndromes; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Plasmacytoma; Primary Myelofibrosis; Sandhoff Disease; Severe Combined Immunodeficiency; Signs and Symptoms; Tay-Sachs Disease; Thalassemia; Wolman Disease; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Ganglioneuroblastoma; Graft vs Host Disease; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Sarcoma, Ewing; Thrombocythemia, Essential; Thrombosis; Hematopoietic Stem Cell Transplantation; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms DNA inhibitor

Small molecule

Approved

OTHER

INJECTION; ORAL

Acquired Immunodeficiency Syndrome; Anemia; Blast Crisis; Brain Neoplasms; Chordoma; Genetic Diseases, Inborn; HIV Infections; Leukemia, Myeloid; Liver Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Osteogenesis Imperfecta; Ovarian Neoplasms; Retinoblastoma; Wiskott-Aldrich Syndrome; X-Linked Combined Immunodeficiency Diseases; Adrenoleukodystrophy; Anemia, Sickle Cell; beta-Thalassemia; Breast Neoplasms, Male; Central Nervous System Neoplasms; Epidermolysis Bullosa; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immune System Diseases; Immunologic Deficiency Syndromes; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Plasmacytoma; Primary Myelofibrosis; Sandhoff Disease; Severe Combined Immunodeficiency; Signs and Symptoms; Tay-Sachs Disease; Thalassemia; Wolman Disease; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Ganglioneuroblastoma; Graft vs Host Disease; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Sarcoma, Ewing; Thrombocythemia, Essential; Thrombosis; Hematopoietic Stem Cell Transplantation; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms

DNA inhibitor


Small molecule Approved OTHER INTRALYMPHATIC; INTRAUTERINE Osteoarthritis, Knee; Carcinoma, Hepatocellular; Liver Neoplasms; Thrombosis; Neoplasms Diagnostic agent


Small molecule Approved OTHER ORAL Unknown Nematode GABA-A receptor positive modulator

Small molecule

Approved

OTHER

ORAL; TRANSDERMAL

Alcoholism; Hypotension, Orthostatic; Opioid-Related Disorders; Postoperative Complications; Amphetamine-Related Disorders; Brain Injuries; Chronic Pain; Cocaine-Related Disorders; Feeding and Eating Disorders; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Anemia, Sickle Cell; Asthenia; Bipolar Disorder; Brain Neoplasms; Delirium; Dementia; Depressive Disorder; Depressive Disorder, Major; Fatigue; Hematologic Neoplasms; Multiple Sclerosis; Neoplasms; Tobacco Use Disorder; Attention Deficit Disorder with Hyperactivity; Narcolepsy

Dopamine transporter inhibitor

Small molecule

Approved

MUSCULOSKELETAL; OTHER

ORAL

Anemia, Diamond-Blackfan; Canavan Disease; Diabetes Mellitus, Type 2; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Lymphoma, Primary Effusion; Respiratory Syncytial Virus Infections; Status Asthmaticus; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; AIDS-Associated Nephropathy; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Chemical and Drug Induced Liver Injury; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Geographic Atrophy; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hematologic Neoplasms; Hemophilia A; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hepatitis C; HIV Infections; Hypersensitivity; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Premature Birth; Primary Myelofibrosis; Pulmonary Fibrosis; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Kidney Failure, Chronic; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neoplasms, Plasma Cell; Neuroblastoma; Pain; Pemphigoid, Bullous; Pericarditis; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Brain Neoplasms; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Dermatomyositis; Endocrine System Diseases; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior

Glucocorticoid receptor agonist


Small molecule Approved OTHER ORAL Altitude Sickness Dopamine D2 receptor antagonist


Small molecule Approved OTHER ORAL Unknown Muscarinic acetylcholine receptor M1 antagonist


Small molecule Approved OTHER RECTAL Cardiotoxicity; Multiple Myeloma; Genital Neoplasms, Female; Headache; Migraine Disorders; Nausea; Anxiety; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia Dopamine D2 receptor antagonist


Small molecule Approved OTHER ORAL Breast Neoplasms; Hypogonadism; Neoplasms; Orchitis Androgen Receptor agonist


Small molecule Approved OTHER ORAL Hypertension Synaptic vesicular amine transporter inhibitor


Small molecule Approved OTHER RECTAL Colonic Neoplasms; Delirium; Glioblastoma; Neonatal Abstinence Syndrome; Severe Acute Respiratory Syndrome; Conduct Disorder; Porphyrias; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia D2-like dopamine receptor antagonist


Small molecule Approved OTHER OPHTHALMIC Glaucoma Acetylcholinesterase inhibitor