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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
REBAUDIOSIDE A
1
Oligosaccharide
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2
Unknown
REBAUDIOSIDE A
×
Maximum Phase:
1
First Approval:
None
UNII:
B3FUD0528F
Molecule Type:
Oligosaccharide
Molecular Formula:
C44H70O23
Molecular Weight:
967.02
AlogP:
-5.11
PSA:
374.13
HBD:
14.0
HBA:
#RotB:
12.0
Source:
TALINOLOL
1
Small molecule
Investigational
Unknown
Unknown
Cardiovascular Diseases; Obesity, Morbid
Unknown
TALINOLOL
×
Maximum Phase:
1
First Approval:
None
UNII:
3S82268BKG
Molecule Type:
Small molecule
Molecular Formula:
C20H33N3O3
Molecular Weight:
363.5
AlogP:
3.27
PSA:
82.62
HBD:
4.0
HBA:
#RotB:
7.0
Source:
LODAPOLIMAB
1
Antibody
Investigational
Unknown
Unknown
Breast Neoplasms; Melanoma; Neoplasms; Pancreatic Neoplasms
Unknown
LODAPOLIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
NR4MAD6PPB
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MCLA-158
1
Unknown
Investigational
Unknown
Unknown
Colorectal Neoplasms
Unknown
MCLA-158
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OXI-4503
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms
Unknown
OXI-4503
×
Maximum Phase:
1
First Approval:
None
UNII:
JH6Z94GLUD
Molecule Type:
Small molecule
Molecular Formula:
C18H22O12P2
Molecular Weight:
492.31
AlogP:
2.83
PSA:
170.44
HBD:
4.0
HBA:
#RotB:
10.0
Source:
VT-1598
1
Small molecule
Investigational
Unknown
Unknown
Coccidioidomycosis
Unknown
VT-1598
×
Maximum Phase:
1
First Approval:
None
UNII:
AV9K9X720D
Molecule Type:
Small molecule
Molecular Formula:
C31H20F4N6O2
Molecular Weight:
584.53
AlogP:
4.88
PSA:
109.74
HBD:
1.0
HBA:
#RotB:
8.0
Source:
PEN-866
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PEN-866
×
Maximum Phase:
1
First Approval:
None
UNII:
56DL1J49LR
Molecule Type:
Small molecule
Molecular Formula:
C49H49N7O9
Molecular Weight:
879.97
AlogP:
6.97
PSA:
207.03
HBD:
4.0
HBA:
#RotB:
9.0
Source:
MCAF5352A
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
MCAF5352A
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RO-4987655
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
RO-4987655
×
Maximum Phase:
1
First Approval:
None
UNII:
I3733P75ML
Molecule Type:
Small molecule
Molecular Formula:
C20H19F3IN3O5
Molecular Weight:
565.29
AlogP:
3.16
PSA:
100.13
HBD:
3.0
HBA:
#RotB:
8.0
Source:
IMC-1C11
1
Antibody
Investigational
Unknown
Unknown
Unknown
Vascular endothelial growth factor receptor 2 inhibitor
IMC-1C11
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-5099
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AZD-5099
×
Maximum Phase:
1
First Approval:
None
UNII:
33BLU33GDV
Molecule Type:
Small molecule
Molecular Formula:
C21H27Cl2N5O6S
Molecular Weight:
548.45
AlogP:
2.57
PSA:
145.88
HBD:
4.0
HBA:
#RotB:
9.0
Source:
S-55746
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Myelodysplastic Syndromes
Unknown
S-55746
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HYDROXYNORKETAMINE, (2R,6R)-, HYDROCHLORIDE
1
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major
Unknown
HYDROXYNORKETAMINE, (2R,6R)-, HYDROCHLORIDE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H15Cl2NO2
Molecular Weight:
276.16
AlogP:
1.61
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
SUPINOXIN
1
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Unknown
SUPINOXIN
×
Maximum Phase:
1
First Approval:
None
UNII:
ZU8OM8V5WF
Molecule Type:
Small molecule
Molecular Formula:
C22H24FN5O4
Molecular Weight:
441.46
AlogP:
3.15
PSA:
89.05
HBD:
1.0
HBA:
#RotB:
5.0
Source:
SGI-1776
1
Small molecule
Investigational
Unknown
Unknown
Leukemia; Lymphoma, Non-Hodgkin; Prostatic Neoplasms, Castration-Resistant
Serine/threonine-protein kinase PIM inhibitor
SGI-1776
×
Maximum Phase:
1
First Approval:
None
UNII:
72AUA0603W
Molecule Type:
Small molecule
Molecular Formula:
C20H22F3N5O
Molecular Weight:
405.42
AlogP:
4.05
PSA:
54.69
HBD:
1.0
HBA:
#RotB:
5.0
Source:
IT-139
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
IT-139
×
Maximum Phase:
1
First Approval:
None
UNII:
7OSJ9KS483
Molecule Type:
Small molecule
Molecular Formula:
C14H12Cl4N4NaRu
Molecular Weight:
502.15
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
TUROFEXORATE ISOPROPYL
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Bile acid receptor FXR agonist
TUROFEXORATE ISOPROPYL
×
Maximum Phase:
1
First Approval:
None
UNII:
S6KDM312I5
Molecule Type:
Small molecule
Molecular Formula:
C25H24F2N2O3
Molecular Weight:
438.47
AlogP:
5.17
PSA:
62.4
HBD:
1.0
HBA:
#RotB:
3.0
Source:
ELTANEXOR
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ELTANEXOR
×
Maximum Phase:
1
First Approval:
None
UNII:
Q59IQJ9NTK
Molecule Type:
Small molecule
Molecular Formula:
C17H10F6N6O
Molecular Weight:
428.3
AlogP:
3.26
PSA:
99.58
HBD:
1.0
HBA:
#RotB:
4.0
Source:
AZD-7762
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Serine/threonine-protein kinase Chk1 inhibitor
AZD-7762
×
Maximum Phase:
1
First Approval:
None
UNII:
5D822Y3L1H
Molecule Type:
Small molecule
Molecular Formula:
C17H19FN4O2S
Molecular Weight:
362.43
AlogP:
2.53
PSA:
96.25
HBD:
4.0
HBA:
#RotB:
4.0
Source:
RG-7741
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma
Serine/threonine-protein kinase Chk1 inhibitor
RG-7741
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD0156
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
AZD0156
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BALAFILCON A
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BALAFILCON A
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
UNESBULIN
1
Small molecule
Investigational
Unknown
Unknown
Diffuse Intrinsic Pontine Glioma; Leiomyosarcoma; Neoplasms; Ovarian Neoplasms
Unknown
UNESBULIN
×
Maximum Phase:
1
First Approval:
None
UNII:
Z4HZ70S62Q
Molecule Type:
Small molecule
Molecular Formula:
C19H13F5N6
Molecular Weight:
420.35
AlogP:
4.75
PSA:
81.65
HBD:
2.0
HBA:
#RotB:
3.0
Source:
LB80380 MALEATE SALT
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
LB80380 MALEATE SALT
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HYDROXYNORKETAMINE, (2R,6R)
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HYDROXYNORKETAMINE, (2R,6R)
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C12H14ClNO2
Molecular Weight:
239.7
AlogP:
1.61
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
1.0
Source:
SONIFILAN
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
SONIFILAN
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SELITRECTINIB
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Neurotrophic tyrosine kinase receptor inhibitor
SELITRECTINIB
×
Maximum Phase:
1
First Approval:
None
UNII:
0J45910S3X
Molecule Type:
Small molecule
Molecular Formula:
C20H21FN6O
Molecular Weight:
380.43
AlogP:
2.67
PSA:
75.42
HBD:
1.0
HBA:
#RotB:
0.0
Source:
ML-246
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ML-246
×
Maximum Phase:
1
First Approval:
None
UNII:
Q6A9F9DSX5
Molecule Type:
Small molecule
Molecular Formula:
C31H30N4O
Molecular Weight:
474.61
AlogP:
6.18
PSA:
66.83
HBD:
2.0
HBA:
#RotB:
5.0
Source:
PEGTIBATINASE
1
Enzyme
Investigational
Unknown
Unknown
Homocystinuria
Unknown
PEGTIBATINASE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-1208
1
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma; Neoplasms
Serine/threonine-protein kinase PIM inhibitor
AZD-1208
×
Maximum Phase:
1
First Approval:
None
UNII:
S98NFM1378
Molecule Type:
Small molecule
Molecular Formula:
C21H21N3O2S
Molecular Weight:
379.49
AlogP:
3.61
PSA:
75.43
HBD:
2.0
HBA:
#RotB:
3.0
Source:
BTA-9881
1
Small molecule
Investigational
Unknown
Unknown
Respiratory Syncytial Virus Infections
Unknown
BTA-9881
×
Maximum Phase:
1
First Approval:
None
UNII:
9VR1J6U4XG
Molecule Type:
Small molecule
Molecular Formula:
C21H15ClN4O2
Molecular Weight:
390.83
AlogP:
2.94
PSA:
66.4
HBD:
0.0
HBA:
#RotB:
2.0
Source:
BIO89-100
1
Unknown
Investigational
Unknown
Unknown
Hypertriglyceridemia; Non-alcoholic Fatty Liver Disease
Unknown
BIO89-100
×
Maximum Phase:
1
First Approval:
None
UNII:
UO870O6MFS
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VORSETUZUMAB MAFODOTIN
1
Antibody
Investigational
Unknown
Unknown
Carcinoma, Renal Cell
CD70 antigen binding agent
VORSETUZUMAB MAFODOTIN
×
Maximum Phase:
1
First Approval:
None
UNII:
699619YVTQ
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
E7107
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Unknown
E7107
×
Maximum Phase:
1
First Approval:
None
UNII:
R60DZX1E2N
Molecule Type:
Small molecule
Molecular Formula:
C40H66N2O9
Molecular Weight:
718.97
AlogP:
5.05
PSA:
152.53
HBD:
4.0
HBA:
#RotB:
10.0
Source:
TIBULIZUMAB
1
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Sjogren's Syndrome
Interleukin 17A inhibitor
TIBULIZUMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
42HQ15W1ZF
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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88
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90
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Maximum Phase
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Molecular Formula
Molecular Weight
ALogP
PSA