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Total: 6532
Small molecule
Approved
Unknown
Unknown
Crohn Disease; Gastroparesis; Anxiety; Dementia; Depressive Disorder; Hyperemesis Gravidarum; Migraine with Aura; Migraine without Aura; Nausea; Pain; Schizophrenia; Vertigo; Vomiting; Hypersensitivity; Pruritus
Unknown
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Orthostatic Intolerance
Unknown
Small molecule
Approved
OTHER
ORAL
Amphetamine-Related Disorders; HIV Infections; Multiple Myeloma; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Alcohol-Related Disorders; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cocaine-Related Disorders; Glioblastoma; Melanoma; Neoplasms, Germ Cell and Embryonal; Opioid-Related Disorders; Severe Acute Respiratory Syndrome; Alcoholism; Ectoparasitic Infestations
Aldehyde dehydrogenase inhibitor
Small molecule
Approved
OTHER
ORAL
Chondrocalcinosis; Alcoholism; Brain Injuries; Diabetes Mellitus, Type 2; Influenza in Birds; Neoplasms; Cellulitis; Heart Failure; Heart Failure, Systolic; Infections; Obesity; Urinary Tract Infections; Gout
Solute carrier family 22 member 11 inhibitor
Small molecule
Approved
Unknown
Unknown
Urinary Bladder, Neurogenic; Digestive System Diseases
Unknown
Small molecule
Approved
OTHER
TOPICAL
Ischemic Stroke; Mucositis; Multiple Sclerosis; Neoplasms; Prostatic Neoplasms; Graves Ophthalmopathy; Myalgia; Thyrotoxicosis; Alzheimer Disease; Chagas Disease; Colorectal Neoplasms; HIV Infections; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Stomatitis; Tuberculosis; Urinary Bladder Neoplasms; Dandruff; Dermatitis, Seborrheic; Pruritus; Tinea
Unknown
Small molecule
Approved
OTHER
ORAL
Unknown
Histamine H2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Obesity; Vascular Diseases; Hypertension; Hypotension, Orthostatic; Infections; Mucositis; Neoplasms; Orthostatic Intolerance; Ovarian Cysts; Pain; Stomatitis; Acute Lung Injury; Bronchiolitis; Cognitive Dysfunction; Mydriasis; Shock, Septic; Stress Disorders, Post-Traumatic; Common Cold; Eye Diseases; Fecal Incontinence; Hypotension; Influenza, Human; Ischemic Stroke; Respiratory Tract Infections; Rhinitis, Allergic, Seasonal; Stroke; Cardiovascular Diseases; Eye Manifestations; Nasal Obstruction
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL
Osteomyelitis; Psoriasis; Rheumatic Heart Disease; HIV Infections; Syphilis; Yaws; Bacterial Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
Unknown
Unknown
Hypoglycemia; Obesity; Presbyopia; Mydriasis; Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Arthritis, Rheumatoid; Neoplasms; Adenocarcinoma; Biliary Tract Diseases; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Colorectal Neoplasms; Nasopharyngeal Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Glucosephosphate Dehydrogenase Deficiency; Obesity; Severe Acute Respiratory Syndrome; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Malaria
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL
Osteomyelitis; Melanoma; Acquired Immunodeficiency Syndrome; Diabetic Foot; Tuberculosis, Multidrug-Resistant; Ulcer; HIV Infections; Silicosis; Tuberculosis; Tuberculosis, Pulmonary
Enoyl-[acyl-carrier-protein] reductase inhibitor
Small molecule
Approved
OTHER
FOR RX COMPOUNDING; INJECTION; ORAL; RECTAL; TOPICAL; VAGINAL
Fibromyalgia; HIV Infections; Insulin Resistance; Diabetes Mellitus, Type 1; Infections; Lymphoma, Large-Cell, Anaplastic; Obesity; Tobacco Use Disorder; Addison Disease; Adrenal Cortex Neoplasms; Aging; Atrial Fibrillation; Borderline Personality Disorder; Central Nervous System Neoplasms; Conjunctivitis, Allergic; Heart Failure; Leukemia, Mast-Cell; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Large B-Cell, Diffuse; Melanoma; Memory Disorders; Multiple Myeloma; Myocardial Infarction; Neoplasms; Opioid-Related Disorders; Phobic Disorders; Wounds and Injuries; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Alcoholism; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Bronchopulmonary Dysplasia; Dermatitis; Eczema; Heart Arrest; Hypotension; Hypoxia; Influenza, Human; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Lymphoma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Oral Submucous Fibrosis; Pneumonia, Viral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Sepsis; Severe Acute Respiratory Syndrome; Shock, Septic; Asthma; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Eye Diseases; Hemorrhoids; Herpes Labialis; Inflammation; Nasal Obstruction; Osteoarthritis; Otitis Externa; Pneumonia
Glucocorticoid receptor agonist
Small molecule
Approved
Unknown
Unknown
Bradycardia; Myalgia; Stroke
Unknown
Small molecule
Unknown
Unknown
Unknown
Cardiovascular Diseases; Prostatic Neoplasms, Castration-Resistant; Pheochromocytoma
Adrenergic receptor alpha antagonist
Small molecule
Approved
OTHER
TOPICAL
Unknown
Tyrosinase inhibitor
Small molecule
Approved
Unknown
Unknown
Anemia, Sickle Cell; Constipation; Neck Pain; Osteoarthritis; Myopia; Toothache; Cough; Pain
Unknown
Small molecule
Approved
OTHER
ORAL
Astrocytoma; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Leukemia, Lymphoid; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Amidophosphoribosyltransferase inhibitor
Small molecule
Approved
Unknown
Unknown
Digestive System Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Eye Infections
Bacterial dihydropteroate synthase inhibitor
Small molecule
Approved
OTHER
SUBCUTANEOUS
Fanconi Anemia; HIV Infections; Inflammation; Leukemia, Plasma Cell; Malaria; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Anemia, Aplastic; Anemia, Sickle Cell; Blast Crisis; Burkitt Lymphoma; Carcinoma, Merkel Cell; Central Serous Chorioretinopathy; Colitis, Ulcerative; Colorectal Neoplasms; Constriction, Pathologic; Coronary Disease; Ependymoma; Fibromatosis, Aggressive; Hematologic Neoplasms; Hemoglobinuria, Paroxysmal; Histiocytosis, Langerhans-Cell; Immunoblastic Lymphadenopathy; Kidney Neoplasms; Leukemia, Hairy Cell; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelomonocytic, Juvenile; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Peripheral; Mesothelioma; Multiple Myeloma; Myasthenia Gravis; Myelodysplastic-Myeloproliferative Diseases; Myocardial Infarction; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteopetrosis; Ovarian Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Schizophrenia; Severe Combined Immunodeficiency; Sezary Syndrome; Shwachman-Diamond Syndrome; Urticaria; Waldenstrom Macroglobulinemia; Wiskott-Aldrich Syndrome; Alopecia Areata; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Arthritis, Psoriatic; Asthma; Brain Neoplasms; Carcinoma, Squamous Cell; Cardiovascular Diseases; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Gestational Trophoblastic Disease; Giant Cell Arteritis; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Head and Neck Neoplasms; Hearing Loss, Sensorineural; Hodgkin Disease; Hydatidiform Mole; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Macular Edema; Medulloblastoma; Multiple Sclerosis; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive; Osteoarthritis; Osteosarcoma; Pemphigoid, Bullous; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy, Ectopic; Retroperitoneal Fibrosis; Sarcoidosis; Sarcoma; Spondylitis, Ankylosing; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveitis; Uveitis, Intermediate; Vasculitis; Vitiligo; Vitreoretinopathy, Proliferative; Adenoma; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Breast Neoplasms; Choriocarcinoma; Communicable Diseases; Immune System Diseases; Lung Neoplasms; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Mycosis Fungoides; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psoriasis
Dihydrofolate reductase inhibitor
Small molecule
Approved
OTHER
ORAL
Anemia; Cocaine-Related Disorders; Leukemia; Lymphoma; Neuroblastoma; Anemia, Sickle Cell; Optic Neuritis; Pancreatic Neoplasms; Polyneuropathies; Thalassemia; Wounds and Injuries; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
Unknown
Unknown
Chalazion; Osteomyelitis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Burns; Lymphoma, Non-Hodgkin; Candidiasis, Vulvovaginal; Conjunctivitis, Inclusion; Helicobacter Infections; Periodontitis; Vaginosis, Bacterial; Bacterial Infections; Eye Infections; Infections
Bacterial 70S ribosome inhibitor
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections; Cystitis; Urinary Tract Infections
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Unknown
Unknown
Unknown
Pain
Unknown
Small molecule
Approved
OTHER
ORAL
Andersen Syndrome; Hypotension, Orthostatic; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures
Carbonic anhydrase II inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial dihydropteroate synthase inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL
Urinary Bladder, Overactive; Peptic Ulcer
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
ORAL; SUBLINGUAL
Dementia, Vascular; Cardiovascular Diseases
Adrenergic receptor alpha antagonist
Small molecule
Approved
Unknown
Unknown
Polycystic Kidney Diseases; Lung Neoplasms; Rectal Neoplasms; Breast Neoplasms; Cerebral Hemorrhage; Heart Diseases; Heart Failure; Neoplasms; Pre-Eclampsia; Stroke; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Ovarian Neoplasms; Uterine Cervical Neoplasms; Hypertension
Unknown
Small molecule
Approved
Unknown
Unknown
Digestive System Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Amyotrophic Lateral Sclerosis; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Sandhoff Disease; Tay-Sachs Disease; Toxoplasmosis, Cerebral; Anemia; Chorioretinitis; Depressive Disorder; HIV Infections; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth; Schistosomiasis; Schizophrenia; Toxoplasmosis, Congenital; Malaria; Toxoplasmosis
Dihydrofolate reductase inhibitor