DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY ORAL Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Leiomyoma; Lymphoma, Non-Hodgkin; Mesothelioma; Adenomyosis; Adrenal Hyperplasia, Congenital; Anovulation; Carcinoma; Carcinoma, Lobular; Dwarfism; Endometriosis; Fallopian Tube Neoplasms; Hepatopulmonary Syndrome; Inflammatory Breast Neoplasms; Leiomyosarcoma; Lymphangioleiomyomatosis; Ovarian Neoplasms; Peritoneal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Azoospermia; Carcinoma, Intraductal, Noninfiltrating; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypogonadism; Infertility; Menopause; Neoplasm Metastasis; Osteoporosis; Ovarian Hyperstimulation Syndrome; Polycystic Ovary Syndrome; Pregnancy; Breast Neoplasms; Neoplasms Cytochrome P450 19A1 inhibitor

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Leiomyoma; Lymphoma, Non-Hodgkin; Mesothelioma; Adenomyosis; Adrenal Hyperplasia, Congenital; Anovulation; Carcinoma; Carcinoma, Lobular; Dwarfism; Endometriosis; Fallopian Tube Neoplasms; Hepatopulmonary Syndrome; Inflammatory Breast Neoplasms; Leiomyosarcoma; Lymphangioleiomyomatosis; Ovarian Neoplasms; Peritoneal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Azoospermia; Carcinoma, Intraductal, Noninfiltrating; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypogonadism; Infertility; Menopause; Neoplasm Metastasis; Osteoporosis; Ovarian Hyperstimulation Syndrome; Polycystic Ovary Syndrome; Pregnancy; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor


Small molecule Approved CANCER; OTHER ORAL Carcinoma, Merkel Cell; Central Nervous System Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Urinary Bladder Neoplasms; Anus Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Brain Diseases; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Hand-Foot Syndrome; Liver Neoplasms; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colonic Neoplasms; Neoplasms DNA inhibitor

Small molecule

Approved

CANCER; OTHER

ORAL

Carcinoma, Merkel Cell; Central Nervous System Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Urinary Bladder Neoplasms; Anus Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Brain Diseases; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Hand-Foot Syndrome; Liver Neoplasms; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colonic Neoplasms; Neoplasms

DNA inhibitor


Small molecule Approved Unknown Unknown Foramen Ovale, Patent; Migraine with Aura; Pulmonary Edema; Skin Diseases; Acute Kidney Injury; Anemia, Sickle Cell; Brain Diseases; Coronary Disease; Heart Diseases; Hepatitis C; Infertility, Female; Ischemic Stroke; Liver Cirrhosis; Lymphangioma; Mycobacterium Infections; Myelodysplastic Syndromes; Pulmonary Embolism; Severe Acute Respiratory Syndrome; Urinary Incontinence; Brain Injuries; Bronchopulmonary Dysplasia; Carcinoma, Non-Small-Cell Lung; Cerebral Small Vessel Diseases; Cystic Fibrosis; Fetal Growth Retardation; Hypoplastic Left Heart Syndrome; Infertility; Muscular Dystrophy, Duchenne; Parkinson Disease; Pre-Eclampsia; Pregnancy; Premature Birth; Priapism; Prostatic Hyperplasia; Raynaud Disease; Scleroderma, Localized; Sexual Dysfunction, Physiological; Skin Ulcer; Arterial Occlusive Diseases; Coronary Vasospasm; Diabetes Mellitus; Eisenmenger Complex; Glaucoma; Heart Failure; Hypertension; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung Diseases; Peripheral Arterial Disease; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Erectile Dysfunction Unknown

Small molecule

Approved

Unknown

Foramen Ovale, Patent; Migraine with Aura; Pulmonary Edema; Skin Diseases; Acute Kidney Injury; Anemia, Sickle Cell; Brain Diseases; Coronary Disease; Heart Diseases; Hepatitis C; Infertility, Female; Ischemic Stroke; Liver Cirrhosis; Lymphangioma; Mycobacterium Infections; Myelodysplastic Syndromes; Pulmonary Embolism; Severe Acute Respiratory Syndrome; Urinary Incontinence; Brain Injuries; Bronchopulmonary Dysplasia; Carcinoma, Non-Small-Cell Lung; Cerebral Small Vessel Diseases; Cystic Fibrosis; Fetal Growth Retardation; Hypoplastic Left Heart Syndrome; Infertility; Muscular Dystrophy, Duchenne; Parkinson Disease; Pre-Eclampsia; Pregnancy; Premature Birth; Priapism; Prostatic Hyperplasia; Raynaud Disease; Scleroderma, Localized; Sexual Dysfunction, Physiological; Skin Ulcer; Arterial Occlusive Diseases; Coronary Vasospasm; Diabetes Mellitus; Eisenmenger Complex; Glaucoma; Heart Failure; Hypertension; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung Diseases; Peripheral Arterial Disease; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Erectile Dysfunction

Unknown


Small molecule Approved Unknown Unknown Renal Insufficiency; Ischemic Stroke; Pneumonia, Viral; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Stroke; Venous Thromboembolism; Acute Coronary Syndrome; Coronary Disease; Myocardial Infarction; Thrombosis Unknown


Small molecule Approved OTHER OPHTHALMIC Central Serous Chorioretinopathy; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension Carbonic anhydrase II inhibitor


Small molecule Approved Unknown Unknown Migraine with Aura; Migraine without Aura; Migraine Disorders Unknown


Small molecule Approved OTHER INTRAVESICAL Carcinoma in Situ; Urinary Bladder Neoplasms; Carcinoma; Neoplasms DNA inhibitor


Small molecule Approved Unknown Unknown Chronic Kidney Disease-Mineral and Bone Disorder; Fibrous Dysplasia of Bone; Lung Neoplasms; Menopause; Back Pain; Bone Diseases, Metabolic; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Spinal Cord Injuries; Bone Diseases Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY INJECTION; INTRAVENOUS; ORAL Breast Neoplasms; Multiple Myeloma; Neoplasms; Rectal Neoplasms; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic Vitamin D receptor agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY

INJECTION; INTRAVENOUS; ORAL

Breast Neoplasms; Multiple Myeloma; Neoplasms; Rectal Neoplasms; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic

Vitamin D receptor agonist


Small molecule Approved OTHER ORAL Depressive Disorder, Major; Obesity; Breast Carcinoma In Situ; Carcinoma, Hepatocellular; Hepatolenticular Degeneration; Hypotension, Orthostatic; Inflammation; Keratosis, Actinic; Mouth Neoplasms; Myeloproliferative Disorders; Neuroblastoma; Tuberculosis; Uterine Cervical Neoplasms; Amyotrophic Lateral Sclerosis; Back Pain; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Cervical Intraepithelial Neoplasia; Esophageal Neoplasms; Facial Pain; Glioblastoma; Glioma; Graves Ophthalmopathy; Lymphangioleiomyomatosis; Medulloblastoma; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Ovarian Neoplasms; Papilloma; Papillomavirus Infections; Paraproteinemias; Peritoneal Neoplasms; Pre-Eclampsia; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sarcoma; Schizophrenia; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Stomatitis; Temporomandibular Joint Disorders; Tonsillitis; Toothache; Urinary Bladder Neoplasms; Uterine Neoplasms; Adenoma; Alzheimer Disease; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Colonic Neoplasms; Colorectal Neoplasms; Depression, Postpartum; Depressive Disorder; Gout; Hand-Foot Syndrome; Head and Neck Neoplasms; Hypertension; Influenza, Human; Liver Neoplasms; Low Back Pain; Lung Neoplasms; Macular Degeneration; Memory Disorders; Nasopharyngeal Neoplasms; Osteoarthritis, Hip; Osteoarthritis, Knee; Pancreatic Neoplasms; Pharyngitis; Rectal Neoplasms; Tobacco Use Disorder; Wounds and Injuries; Acute Pain; Adenomatous Polyposis Coli; Arthritis, Juvenile; Arthritis, Rheumatoid; Dysmenorrhea; Hemorrhage; Migraine Disorders; Neoplasms; Osteoarthritis; Pain; Peptic Ulcer; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stroke Cyclooxygenase-2 inhibitor

Small molecule

Approved

OTHER

ORAL

Depressive Disorder, Major; Obesity; Breast Carcinoma In Situ; Carcinoma, Hepatocellular; Hepatolenticular Degeneration; Hypotension, Orthostatic; Inflammation; Keratosis, Actinic; Mouth Neoplasms; Myeloproliferative Disorders; Neuroblastoma; Tuberculosis; Uterine Cervical Neoplasms; Amyotrophic Lateral Sclerosis; Back Pain; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Cervical Intraepithelial Neoplasia; Esophageal Neoplasms; Facial Pain; Glioblastoma; Glioma; Graves Ophthalmopathy; Lymphangioleiomyomatosis; Medulloblastoma; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Ovarian Neoplasms; Papilloma; Papillomavirus Infections; Paraproteinemias; Peritoneal Neoplasms; Pre-Eclampsia; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sarcoma; Schizophrenia; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Stomatitis; Temporomandibular Joint Disorders; Tonsillitis; Toothache; Urinary Bladder Neoplasms; Uterine Neoplasms; Adenoma; Alzheimer Disease; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Colonic Neoplasms; Colorectal Neoplasms; Depression, Postpartum; Depressive Disorder; Gout; Hand-Foot Syndrome; Head and Neck Neoplasms; Hypertension; Influenza, Human; Liver Neoplasms; Low Back Pain; Lung Neoplasms; Macular Degeneration; Memory Disorders; Nasopharyngeal Neoplasms; Osteoarthritis, Hip; Osteoarthritis, Knee; Pancreatic Neoplasms; Pharyngitis; Rectal Neoplasms; Tobacco Use Disorder; Wounds and Injuries; Acute Pain; Adenomatous Polyposis Coli; Arthritis, Juvenile; Arthritis, Rheumatoid; Dysmenorrhea; Hemorrhage; Migraine Disorders; Neoplasms; Osteoarthritis; Pain; Peptic Ulcer; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stroke

Cyclooxygenase-2 inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Diabetes Mellitus, Type 2; Hepatitis C; Lymphoma, Non-Hodgkin; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Acquired Immunodeficiency Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved OTHER ORAL Cognitive Dysfunction; Hypotension, Orthostatic; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Narcolepsy; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Apnea, Obstructive; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity Dopamine transporter inhibitor

Small molecule

Approved

OTHER

ORAL

Cognitive Dysfunction; Hypotension, Orthostatic; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Narcolepsy; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Apnea, Obstructive; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity

Dopamine transporter inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY ORAL Breast Neoplasms; Graft vs Host Disease; HIV Infections; Melanoma; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis Dihydroorotate dehydrogenase inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY

ORAL

Breast Neoplasms; Graft vs Host Disease; HIV Infections; Melanoma; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis

Dihydroorotate dehydrogenase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Cocaine-Related Disorders; Neuroblastoma; Alcoholism; Brain Injuries; Gambling; Obsessive-Compulsive Disorder; Pick Disease of the Brain; Schizophrenia; Tobacco Use Disorder; Liver Failure; Parkinson Disease Catechol O-methyltransferase inhibitor


Small molecule Approved Unknown Unknown Anemia, Hemolytic, Autoimmune; Bronchopulmonary Dysplasia; HIV Infections; Immune System Diseases; Neoplasms; Non-alcoholic Fatty Liver Disease; Respiratory Tract Diseases; Alzheimer Disease; Anemia, Sickle Cell; Cough; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premature Birth; Severe Dengue; Sleep Apnea Syndromes; Status Asthmaticus; Arthritis, Rheumatoid; Eosinophilic Esophagitis; Pain; Respiratory Sounds; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Asthma; Asthma, Exercise-Induced; Lung Diseases, Obstructive; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal Unknown

Small molecule

Approved

Unknown

Anemia, Hemolytic, Autoimmune; Bronchopulmonary Dysplasia; HIV Infections; Immune System Diseases; Neoplasms; Non-alcoholic Fatty Liver Disease; Respiratory Tract Diseases; Alzheimer Disease; Anemia, Sickle Cell; Cough; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premature Birth; Severe Dengue; Sleep Apnea Syndromes; Status Asthmaticus; Arthritis, Rheumatoid; Eosinophilic Esophagitis; Pain; Respiratory Sounds; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Asthma; Asthma, Exercise-Induced; Lung Diseases, Obstructive; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal

Unknown


Small molecule Approved Unknown Unknown Neuralgia; Kidney Calculi; Low Back Pain; Pain; Pelvic Organ Prolapse; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence Unknown


Small molecule Approved DERMATOLOGY; OTHER ORAL Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyloidosis; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Pain; Pancreatitis, Chronic; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Thalassemia; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Carcinoma, Hepatocellular; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Vascular Malformations; Immune System Diseases; Multiple Myeloma CRL4(CRBN) E3 ubiquitin ligase inhibitor

Small molecule

Approved

DERMATOLOGY; OTHER

ORAL

Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyloidosis; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Pain; Pancreatitis, Chronic; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Thalassemia; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Carcinoma, Hepatocellular; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Vascular Malformations; Immune System Diseases; Multiple Myeloma

CRL4(CRBN) E3 ubiquitin ligase inhibitor


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY ORAL Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Small molecule Approved Unknown Unknown Headache; Migraine Disorders Unknown


Small molecule Unknown Unknown Unknown Autistic Disorder; Panic Disorder; Hot Flashes; Depressive Disorder; Depressive Disorder, Major Serotonin transporter inhibitor


Small molecule Approved OTHER ORAL Unknown Unknown


Small molecule Approved Unknown Unknown Hepatitis C; Acidosis, Lactic; Lipodystrophy; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; HIV Infections; Tuberculosis; Virus Diseases Unknown


Small molecule Approved RESPIRATORY ORAL Osteomyelitis; HIV Infections; Tuberculosis, Pulmonary; Tuberculosis Bacterial DNA-directed RNA polymerase inhibitor


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Pain; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Pain; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Small molecule Approved Unknown Unknown Acute Coronary Syndrome; Child Development Disorders, Pervasive; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Irritable Bowel Syndrome; Opioid-Related Disorders; Panic Disorder; Parkinson Disease; Stroke; Anxiety; Dementia; Depressive Disorder, Major; Obsessive-Compulsive Disorder; Psychomotor Agitation; Schizophrenia; Depressive Disorder Unknown

Small molecule

Approved

Unknown

Acute Coronary Syndrome; Child Development Disorders, Pervasive; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Irritable Bowel Syndrome; Opioid-Related Disorders; Panic Disorder; Parkinson Disease; Stroke; Anxiety; Dementia; Depressive Disorder, Major; Obsessive-Compulsive Disorder; Psychomotor Agitation; Schizophrenia; Depressive Disorder

Unknown


Small molecule Approved EYE; OTHER OPHTHALMIC Osteomyelitis; Cataract; Tuberculosis; Bacterial Infections; Conjunctivitis, Bacterial; Eye Infections; Infections DNA gyrase inhibitor

Small molecule

Approved

Unknown

Anemia; Breast Neoplasms; Erectile Dysfunction; Glomerulosclerosis, Focal Segmental; Malaria; Malaria, Falciparum; Nausea; Neoplasms; Arthritis, Rheumatoid; Asthma; Cognitive Dysfunction; Colitis, Ulcerative; Endometriosis; HIV Infections; Insulin Resistance; Mycosis Fungoides; Non-alcoholic Fatty Liver Disease; Prediabetic State; Sezary Syndrome; Alzheimer Disease; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glucose Intolerance; Hypercholesterolemia; Hypertension; Lipid Metabolism Disorders; Metabolic Diseases; Metabolic Syndrome; Multiple Organ Failure; Prostatic Neoplasms; Diabetes Mellitus

Unknown


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INTRAVENOUS; ORAL

Aphasia; Canavan Disease; Essential Tremor; Stroke; Alzheimer Disease; Anemia, Sickle Cell; Bipolar Disorder; Brain Neoplasms; Cocaine-Related Disorders; Cognitive Dysfunction; Dyskinesia, Drug-Induced; Epilepsy, Absence; Epilepsy, Reflex; Glioblastoma; Glioma; Leukemia, Myeloid, Acute; Neuralgia, Postherpetic; Neuroblastoma; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Polyneuropathies; Psychotic Disorders; Restless Legs Syndrome; Stress Disorders, Post-Traumatic; Torticollis; Alcoholism; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Movement Disorders; Panic Disorder; Schizophrenia; Status Epilepticus; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Epilepsy; Epilepsy, Tonic-Clonic; Seizures

Synaptic vesicle glycoprotein 2A modulator


Small molecule Unknown Unknown Unknown Pain; Pregnancy Sodium channel protein type IV alpha subunit blocker


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Amphetamine-Related Disorders; Gastrointestinal Stromal Tumors; Epilepsy; Obesity; Cocaine-Related Disorders; Parkinson Disease Catechol O-methyltransferase inhibitor

Small molecule

Unknown

Heart Arrest; Anemia; Brain Ischemia; Colorectal Neoplasms; Pressure Ulcer; Pulmonary Disease, Chronic Obstructive; Anemia, Sickle Cell; Cystic Fibrosis; Death, Sudden, Cardiac; Dyspnea; Heart Failure; Infections; Inflammation; Malaria; Myocardial Infarction; Myocardial Ischemia; Neuralgia; Opioid-Related Disorders; Pneumonia, Viral; Pulmonary Embolism; Severe Acute Respiratory Syndrome; Sinusitis; Skin Ulcer; ST Elevation Myocardial Infarction; Stroke; Tinea Pedis; Varicose Ulcer; Acute Kidney Injury; Brain Injuries; Bronchiolitis; Bronchopulmonary Dysplasia; Diabetic Foot; Hernias, Diaphragmatic, Congenital; Hypoxia; Leishmaniasis, Cutaneous; Lung Diseases; Persistent Fetal Circulation Syndrome; Pneumonia; Pneumonia, Aspiration; Premature Birth; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Sepsis; Hypertension, Pulmonary; Respiratory Insufficiency; Respiratory Tract Diseases

Soluble guanylate cyclase activator


Small molecule Approved HEMATOLOGY ORAL Cognitive Dysfunction; HIV Infections; Amyotrophic Lateral Sclerosis; beta-Thalassemia; Dementia; Friedreich Ataxia; Parkinson Disease; Acute Kidney Injury; Hemochromatosis; Pantothenate Kinase-Associated Neurodegeneration; Anemia, Sickle Cell; Thalassemia Unknown


Small molecule Approved Unknown Unknown Pain; Liver Diseases; Ileus; Retinopathy of Prematurity; Apnea; Premature Birth Adenosine receptor antagonist


Small molecule Approved IMMUNE SYSTEM INHALATION Dengue; Diabetes Mellitus, Type 2; Infections; Influenza, Human; Virus Diseases Neuraminidase inhibitor