DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved OTHER ORAL Cystic Fibrosis; Diabetes Mellitus, Type 2; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infertility, Female; Leukemia, Lymphocytic, Chronic, B-Cell; Non-alcoholic Fatty Liver Disease; Bulimia; Bulimia Nervosa; Depressive Disorder; Endometrial Neoplasms; Hidradenitis Suppurativa; Hyperandrogenism; Metrorrhagia; Osteoporosis; Premenstrual Syndrome; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Migraine Disorders; Neural Tube Defects; Polycystic Ovary Syndrome; Pregnancy; Turner Syndrome; Acne Vulgaris; Neoplasms Estrogen receptor alpha agonist

Small molecule

Approved

OTHER

ORAL

Cystic Fibrosis; Diabetes Mellitus, Type 2; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infertility, Female; Leukemia, Lymphocytic, Chronic, B-Cell; Non-alcoholic Fatty Liver Disease; Bulimia; Bulimia Nervosa; Depressive Disorder; Endometrial Neoplasms; Hidradenitis Suppurativa; Hyperandrogenism; Metrorrhagia; Osteoporosis; Premenstrual Syndrome; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Migraine Disorders; Neural Tube Defects; Polycystic Ovary Syndrome; Pregnancy; Turner Syndrome; Acne Vulgaris; Neoplasms

Estrogen receptor alpha agonist


Small molecule Approved Unknown Unknown Endometritis; Appendicitis; Renal Insufficiency, Chronic; Tuberculosis; Diabetic Foot; Gonorrhea; Infections; Osteomyelitis; Pneumonia; Pyelonephritis; Urinary Tract Infections; Bacterial Infections Unknown


Small molecule Approved Unknown Unknown Migraine Disorders Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Urinary Tract Infections; Bronchitis, Chronic; Infections; Pharyngitis; Tonsillitis Bacterial penicillin-binding protein inhibitor


Small molecule Approved Unknown Unknown Alzheimer Disease; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive Unknown


Small molecule Approved Unknown Unknown Hypotension, Orthostatic; Lecithin Cholesterol Acyltransferase Deficiency; Memory Disorders; Obesity; Subarachnoid Hemorrhage; Cocaine-Related Disorders; HIV Infections; Psychotic Disorders; Tobacco Use Disorder; Alzheimer Disease; Anxiety; Autistic Disorder; Dementia, Vascular; Depressive Disorder; Lewy Body Disease; Schizophrenia; Dementia Unknown


Small molecule Approved Unknown Unknown Arthritis, Juvenile; Breast Neoplasms; Child Development Disorders, Pervasive; Hepatitis B, Chronic; Hypertension, Pulmonary; Lymphoma; Neoplasms; Asthma; Autistic Disorder; Cystic Fibrosis; Dyspepsia; Eosinophilic Esophagitis; Neuralgia; Digestive System Diseases; Esophageal Neoplasms; Esophagitis, Peptic; Gastritis; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Nausea; Osteoarthritis; Pre-Eclampsia; Stomach Ulcer; Ulcer; Gastroesophageal Reflux; Peptic Ulcer Unknown

Small molecule

Approved

Unknown

Arthritis, Juvenile; Breast Neoplasms; Child Development Disorders, Pervasive; Hepatitis B, Chronic; Hypertension, Pulmonary; Lymphoma; Neoplasms; Asthma; Autistic Disorder; Cystic Fibrosis; Dyspepsia; Eosinophilic Esophagitis; Neuralgia; Digestive System Diseases; Esophageal Neoplasms; Esophagitis, Peptic; Gastritis; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Nausea; Osteoarthritis; Pre-Eclampsia; Stomach Ulcer; Ulcer; Gastroesophageal Reflux; Peptic Ulcer

Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Hepatitis C; Hepatitis, Chronic; Insulin Resistance; Lymphoma; Tuberculosis; Communicable Diseases; Hepatitis D; Lipodystrophy; Liver Cirrhosis, Biliary; Acquired Immunodeficiency Syndrome; Severe Acute Respiratory Syndrome; Hepatitis B, Chronic; HIV Infections; Infections; Liver Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL

Hepatitis C; Hepatitis, Chronic; Insulin Resistance; Lymphoma; Tuberculosis; Communicable Diseases; Hepatitis D; Lipodystrophy; Liver Cirrhosis, Biliary; Acquired Immunodeficiency Syndrome; Severe Acute Respiratory Syndrome; Hepatitis B, Chronic; HIV Infections; Infections; Liver Diseases

Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Unknown Unknown Unknown Acquired Immunodeficiency Syndrome; Dysmenorrhea; HIV Infections; Prostatic Hyperplasia Progesterone receptor agonist


Small molecule Approved EYE; OTHER OPHTHALMIC Exfoliation Syndrome; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension Prostanoid FP receptor agonist


Small molecule Unknown Unknown Unknown Diabetes Mellitus; Fever; Glaucoma; Heart Failure; Mitral Valve Stenosis; Pancreatic Neoplasms; Asthma; Hepatopulmonary Syndrome; Hernias, Diaphragmatic, Congenital; Hypoplastic Left Heart Syndrome; Liver Cirrhosis; Melanoma; Pulmonary Disease, Chronic Obstructive; Diabetes Mellitus, Type 2; Eisenmenger Complex; Heart Septal Defects, Atrial; Idiopathic Pulmonary Fibrosis; Optic Neuropathy, Ischemic; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Heart Defects, Congenital; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension Endothelin receptor, ET-A/ET-B antagonist

Small molecule

Unknown

Diabetes Mellitus; Fever; Glaucoma; Heart Failure; Mitral Valve Stenosis; Pancreatic Neoplasms; Asthma; Hepatopulmonary Syndrome; Hernias, Diaphragmatic, Congenital; Hypoplastic Left Heart Syndrome; Liver Cirrhosis; Melanoma; Pulmonary Disease, Chronic Obstructive; Diabetes Mellitus, Type 2; Eisenmenger Complex; Heart Septal Defects, Atrial; Idiopathic Pulmonary Fibrosis; Optic Neuropathy, Ischemic; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Heart Defects, Congenital; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension

Endothelin receptor, ET-A/ET-B antagonist


Small molecule Approved Unknown Unknown Pain; Migraine Disorders Unknown


Small molecule Approved Unknown Unknown Acute Lung Injury; Carcinoma, Renal Cell; Colorectal Neoplasms; Desmoplastic Small Round Cell Tumor; Fibrosarcoma; Hematologic Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Pancreatic Neoplasms; Rhinitis, Allergic, Seasonal; Thymoma; Arthritis, Rheumatoid; Breast Neoplasms; Chordoma; Colonic Neoplasms; Fibroma; Fibromatosis, Aggressive; Glioblastoma; Hypereosinophilic Syndrome; Leukemia, Myeloid, Acute; Lung Neoplasms; Malaria, Falciparum; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Spinal Cord Injuries; Stomach Neoplasms; Thyroid Neoplasms; Tuberculosis; Gastrointestinal Stromal Tumors; Graft vs Host Disease; Hypertension, Pulmonary; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Stroke; Neoplasms Unknown

Small molecule

Approved

Unknown

Acute Lung Injury; Carcinoma, Renal Cell; Colorectal Neoplasms; Desmoplastic Small Round Cell Tumor; Fibrosarcoma; Hematologic Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Pancreatic Neoplasms; Rhinitis, Allergic, Seasonal; Thymoma; Arthritis, Rheumatoid; Breast Neoplasms; Chordoma; Colonic Neoplasms; Fibroma; Fibromatosis, Aggressive; Glioblastoma; Hypereosinophilic Syndrome; Leukemia, Myeloid, Acute; Lung Neoplasms; Malaria, Falciparum; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Spinal Cord Injuries; Stomach Neoplasms; Thyroid Neoplasms; Tuberculosis; Gastrointestinal Stromal Tumors; Graft vs Host Disease; Hypertension, Pulmonary; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Stroke; Neoplasms

Unknown


Small molecule Approved CANCER; DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER INJECTION; INTRAVENOUS; IV (INFUSION) Adenocarcinoma; Anemia, Sickle Cell; Chondrosarcoma; Menopause; Neuroblastoma; beta-Thalassemia; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Complex Regional Pain Syndromes; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Low Back Pain; Macular Degeneration; Mesothelioma; Nasopharyngeal Neoplasms; Osteosarcoma; Primary Myelofibrosis; Progeria; Urogenital Neoplasms; Uterine Cervical Neoplasms; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Fractures, Bone; Giant Cell Tumors; Lung Neoplasms; Lymphoma, Non-Hodgkin; Osteoarthritis, Hip; Osteogenesis Imperfecta; Osteonecrosis; Pain; Plasmacytoma; Reflex Sympathetic Dystrophy; Sarcoma; Sarcoma, Ewing; Spinal Cord Injuries; Bone Diseases; Multiple Myeloma; Neoplasm Metastasis; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant Farnesyl diphosphate synthase inhibitor

Small molecule

Approved

CANCER; DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER

INJECTION; INTRAVENOUS; IV (INFUSION)

Adenocarcinoma; Anemia, Sickle Cell; Chondrosarcoma; Menopause; Neuroblastoma; beta-Thalassemia; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Complex Regional Pain Syndromes; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Low Back Pain; Macular Degeneration; Mesothelioma; Nasopharyngeal Neoplasms; Osteosarcoma; Primary Myelofibrosis; Progeria; Urogenital Neoplasms; Uterine Cervical Neoplasms; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Fractures, Bone; Giant Cell Tumors; Lung Neoplasms; Lymphoma, Non-Hodgkin; Osteoarthritis, Hip; Osteogenesis Imperfecta; Osteonecrosis; Pain; Plasmacytoma; Reflex Sympathetic Dystrophy; Sarcoma; Sarcoma, Ewing; Spinal Cord Injuries; Bone Diseases; Multiple Myeloma; Neoplasm Metastasis; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant

Farnesyl diphosphate synthase inhibitor


Small molecule Approved Unknown Unknown Depressive Disorder, Major; Fatigue Syndrome, Chronic; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Nasopharyngeal Neoplasms; Castleman Disease; Hearing Loss, Sensorineural; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Colitis, Ulcerative; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Infections; Virus Diseases Unknown


Small molecule Approved OTHER; UROLOGY AND KIDNEY ORAL Aging; Amyotrophic Lateral Sclerosis; Bulbo-Spinal Atrophy, X-Linked; Prostatitis; Severe Acute Respiratory Syndrome; Alopecia; Hypogonadism; Prostatic Neoplasms, Castration-Resistant; Prostatic Hyperplasia; Prostatic Neoplasms Steroid 5-alpha-reductase inhibitor


Small molecule Approved DERMATOLOGY TOPICAL Netherton Syndrome; Dermatitis, Seborrheic; Dry Eye Syndromes; Lichen Planus, Oral; Lichen Sclerosus et Atrophicus; Vitiligo; Dermatitis; Dermatitis, Perioral; Lichen Planus; Dermatitis, Atopic; Eczema FK506-binding protein 1A inhibitor


Small molecule Approved Unknown Unknown Attention Deficit Disorder with Hyperactivity Unknown


Small molecule Approved OTHER; RESPIRATORY INHALATION Lung Neoplasms; Bronchiolitis Obliterans; Hypersensitivity; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Bronchiectasis; Bronchitis; Tobacco Use Disorder; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive Beta-2 adrenergic receptor agonist


Small molecule Approved Unknown Unknown Hepatitis; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D; HIV Infections; Liver Cirrhosis, Biliary; Severe Acute Respiratory Syndrome; Virus Diseases Unknown


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY ORAL Osteoarthritis, Knee; Pancreatitis; Osteoarthritis; Pain; Pharyngitis; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved EYE; OTHER OPHTHALMIC; TOPICAL Vitiligo; Alopecia; Graves Ophthalmopathy; Glaucoma; Glaucoma, Open-Angle; Hypotrichosis; Ocular Hypertension Prostanoid FP receptor agonist


Small molecule Approved IMMUNE SYSTEM; OTHER INJECTION; INTRAVENOUS; IV (INFUSION); ORAL Asthma; Graft vs Host Disease; Hematologic Neoplasms; HIV Infections; Keratitis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Neutropenia; Aspergillosis, Allergic Bronchopulmonary; Myelodysplastic Syndromes; Candidiasis, Invasive; Leukemia; Leukemia, Myeloid, Acute; Mycoses; Neuroaspergillosis; Aspergillosis; Candidemia; Candidiasis; Fusariosis; Infections Cytochrome P450 51 inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

INJECTION; INTRAVENOUS; IV (INFUSION); ORAL

Asthma; Graft vs Host Disease; Hematologic Neoplasms; HIV Infections; Keratitis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Neutropenia; Aspergillosis, Allergic Bronchopulmonary; Myelodysplastic Syndromes; Candidiasis, Invasive; Leukemia; Leukemia, Myeloid, Acute; Mycoses; Neuroaspergillosis; Aspergillosis; Candidemia; Candidiasis; Fusariosis; Infections

Cytochrome P450 51 inhibitor


Small molecule Approved Unknown Unknown Hyperpigmentation; Lentigo; Melanosis Unknown


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Constipation; Irritable Bowel Syndrome Serotonin 4 (5-HT4) receptor partial agonist

Small molecule

Approved

CANCER; OTHER

INJECTION; INTRAVENOUS

Carcinoid Tumor; Digestive System Diseases; Gastrointestinal Stromal Tumors; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Diseases; Lymphoma, T-Cell, Cutaneous; Melanoma; Myelodysplastic Syndromes; Neuroblastoma; Anus Neoplasms; Breast Neoplasms; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma, Follicular; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Adenocarcinoma, Mucinous; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Signet Ring Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Esophageal Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Neoplasms

DNA inhibitor


Small molecule Approved OTHER; PEDIATRICS ORAL Albinism; Alkaptonuria; Tyrosinemias 4-hydroxyphenylpyruvate dioxygenase inhibitor


Small molecule Unknown Unknown Unknown Glomerulonephritis; Atherosclerosis; Diabetic Nephropathies; Essential Hypertension; Kidney Diseases; Proteinuria; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

OTHER

ORAL

Prostatic Neoplasms, Castration-Resistant; HIV Infections; Hepatitis C, Chronic; Hepatitis D; Non-alcoholic Fatty Liver Disease; Aortic Valve Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Metabolic Syndrome; Metabolism, Inborn Errors; Myocardial Infarction; Cardiovascular Diseases; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II

Niemann-Pick C1-like protein 1 inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Dyspepsia; Gastroesophageal Reflux; Constipation Unknown

Small molecule

Approved

Unknown

Alzheimer Disease; Hepatitis C; Aphasia; Borderline Personality Disorder; Cocaine-Related Disorders; Digestive System Diseases; Fibromyalgia; Panic Disorder; Phobia, Social; Phobic Disorders; Renal Insufficiency, Chronic; Stress Disorders, Post-Traumatic; Stroke; Substance-Related Disorders; Anxiety; Anxiety Disorders; Bipolar Disorder; Carcinoma; Dementia; Depressive Disorder, Major; Hypertension, Pulmonary; Neoplasms; Obsessive-Compulsive Disorder; Schizophrenia; Depressive Disorder

Unknown


Small molecule Approved Unknown Unknown Migraine with Aura; Migraine without Aura; Migraine Disorders Unknown

Small molecule

Approved

CARDIOVASCULAR; OTHER

ORAL

Diabetes Mellitus, Type 2; Atrial Fibrillation; Breast Neoplasms; Central Serous Chorioretinopathy; Diabetic Nephropathies; Hyperparathyroidism, Primary; Cardiomyopathies; Essential Hypertension; Muscular Dystrophy, Duchenne; Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Mineralocorticoid receptor antagonist

Small molecule

Approved

CANCER

INTRAMUSCULAR

Carcinoma, Ductal; Carcinoma, Squamous Cell; Colorectal Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Lymphoma; Lymphoma, Non-Hodgkin; Mesothelioma; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fibrous Dysplasia, Polyostotic; Genital Neoplasms, Female; Hypertension, Pulmonary; Lung Neoplasms; Lupus Erythematosus, Systemic; Ovarian Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Endometrial Stromal; Uterine Neoplasms; Carcinoma, Lobular; Neoplasm Metastasis; Breast Neoplasms; Neoplasms

Estrogen receptor antagonist