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Total: 6532
Small molecule
Approved
OTHER
INHALATION
Unknown
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
OTHER
ORAL
Unknown
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Alpha-1a adrenergic receptor agonist
Small molecule
Approved
OTHER
ORAL
Cough
Slowly adapting pulmonary stretch receptor inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Metabolic Syndrome; Diabetes Mellitus; Lecithin Cholesterol Acyltransferase Deficiency; Kidney Diseases; Atherosclerosis; Coronary Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Kidney Calculi; Pre-Eclampsia; Angina Pectoris; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Liver Cirrhosis; Myocardial Infarction; Nephrotic Syndrome; Renal Insufficiency, Chronic; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL; SUBCUTANEOUS
Pregnancy; Alzheimer Disease; Endometrial Hyperplasia; HIV Infections; Pain; Primary Ovarian Insufficiency; Sleep Apnea Syndromes; Coronary Disease; Diabetes Mellitus; Endometrial Neoplasms; Heart Diseases; Hot Flashes; Hypercholesterolemia; Hypertension; Infertility; Kidney Neoplasms; Lupus Erythematosus, Systemic; Menopause; Menorrhagia; Myocardial Ischemia; Osteoporosis; Prostatic Neoplasms; Thrombosis; Turner Syndrome; Carcinoma, Renal Cell; Endometriosis; Hemorrhage; Hyperplasia; Neoplasms; Uterine Hemorrhage
Progesterone receptor agonist
Small molecule
Approved
Unknown
Unknown
Bulimia Nervosa; Kidney Diseases; Liver Diseases; Substance-Related Disorders; Diabetes Mellitus; Obesity, Morbid; Obesity
Norepinephrine transporter releasing agent
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Unknown
Unknown
Unknown
Obesity
Unknown
Small molecule
Unknown
Unknown
Unknown
Low Back Pain; Neuralgia; Chronic Pain; Gout; Optic Neuritis; Shoulder Impingement Syndrome; Tennis Elbow; Pain; Anemia; Arthritis, Rheumatoid; Asthma; Brain Neoplasms; Bursitis; Communicable Diseases; Dermatitis; Leukemia; Lymphoma; Nephrotic Syndrome; Osteoarthritis; Serum Sickness; Uveitis
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
INJECTION; INTRAVENOUS
Neoplasms, Neuroepithelial; Anemia; Chordoma; Crohn Disease; Fallopian Tube Neoplasms; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Peritoneal Neoplasms; Severe Combined Immunodeficiency; Wiskott-Aldrich Syndrome; Anemia, Sickle Cell; Breast Neoplasms, Male; Ganglioneuroblastoma; Glioma; Hematologic Diseases; Hematologic Neoplasms; Inflammatory Breast Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Osteosarcoma; Primary Myelofibrosis; Sarcoma; Brain Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Graft vs Host Disease; Leukemia; Medulloblastoma; Neuroblastoma; Neuroectodermal Tumors, Primitive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinoblastoma; Adenocarcinoma; Carcinoma; Hodgkin Disease; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases; Hypertension
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Dysthymic Disorder; Somatoform Disorders; Anxiety; Chest Pain; Death, Sudden, Cardiac; Dementia; Digestive System Diseases; Gastroesophageal Reflux; Low Back Pain; Myocardial Infarction; Schizophrenia; Ventricular Fibrillation; Depressive Disorder
Unknown
Small molecule
Unknown
Unknown
Unknown
Hematologic Neoplasms; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Plasmacytoma; Rotator Cuff Injuries; Spinal Stenosis; Ischemia; Peripheral Arterial Disease; Joint Diseases; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Brain Edema; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Corneal Injuries; Crohn Disease; Dermatitis; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Simplex; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Laryngeal Edema; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Transfusion Reaction; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
INJECTION; ORAL
Lymphoma, B-Cell, Marginal Zone; Anemia; Breast Carcinoma In Situ; Carcinoma, Medullary; Carcinoma, Pancreatic Ductal; Chordoma; Desmoplastic Small Round Cell Tumor; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Glomerulosclerosis, Focal Segmental; Head and Neck Neoplasms; Hepatoblastoma; HIV Infections; Leukemia, Plasma Cell; Liposarcoma; Lymphoma, B-Cell; Mesothelioma; Muscular Diseases; Myasthenia Gravis; Mycosis Fungoides; Nasopharyngeal Neoplasms; Nausea; Neoplasm Metastasis; Osteogenesis Imperfecta; Renal Insufficiency; Sarcoma, Synovial; Sezary Syndrome; Stiff-Person Syndrome; Thymoma; Urinary Bladder Neoplasms; Acquired Immunodeficiency Syndrome; Anemia, Sickle Cell; Arthritis, Rheumatoid; Blast Crisis; Breast Neoplasms, Male; Carcinoma, Merkel Cell; Castleman Disease; Colorectal Neoplasms; Crohn Disease; Endometrial Neoplasms; Epidermolysis Bullosa; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Gliosarcoma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Histiocytosis, Langerhans-Cell; Immune System Diseases; Immunologic Deficiency Syndromes; Leukemia, Lymphoid; Leukemia, Myelomonocytic, Juvenile; Leukemia, Prolymphocytic; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Liver Neoplasms; Lupus Erythematosus, Systemic; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Mouth Neoplasms; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Neuromyelitis Optica; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Osteosarcoma; Pancreatic Neoplasms; Peritoneal Neoplasms; Plasmacytoma; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Purpura, Thrombocytopenic, Idiopathic; Rectal Neoplasms; Sandhoff Disease; Sarcoidosis; Skin Neoplasms; Squamous Intraepithelial Lesions; Takayasu Arteritis; Tay-Sachs Disease; Thalassemia; Thyroid Neoplasms; Tuberculosis; Uterine Cervical Neoplasms; Vasculitis; Wolman Disease; Adenocarcinoma; Amyloidosis; Amyloidosis, Familial; Anemia, Aplastic; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Behcet Syndrome; Bone Marrow Failure Disorders; Brain Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Condylomata Acuminata; Ependymoma; Ganglioneuroblastoma; Gestational Trophoblastic Disease; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granuloma, Lethal Midline; Granulomatosis with Polyangiitis; Idiopathic Pulmonary Fibrosis; Immunoblastic Lymphadenopathy; Infertility; Inflammatory Breast Neoplasms; Kidney Diseases; Kidney Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lung Neoplasms; Lupus Nephritis; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Melanoma; Menopause; Mesenchymoma; Microscopic Polyangiitis; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroectodermal Tumors, Primitive; Neutropenia; Ovarian Neoplasms; Pemphigus; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pulmonary Fibrosis; Red-Cell Aplasia, Pure; Renal Insufficiency, Chronic; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Ewing; Scleritis; Scleroderma, Localized; Scleroderma, Systemic; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thrombocytopenia; Triple Negative Breast Neoplasms; Waldenstrom Macroglobulinemia; Wilms Tumor; Breast Neoplasms; Hodgkin Disease; Lymphoma; Multiple Myeloma; Neoplasms; Nephrotic Syndrome
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Anxiety; Cocaine-Related Disorders; Dementia; Depressive Disorder; Schizophrenia; Parkinson Disease
Unknown
Small molecule
Approved
Unknown
Unknown
Chronic Pain; Pain
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Unknown
Acetylcholinesterase inhibitor
Small molecule
Approved
OTHER
ORAL
Altitude Sickness; Uterine Cervical Neoplasms; Glaucoma; Glaucoma, Open-Angle
Carbonic anhydrase II inhibitor
Small molecule
Approved
Unknown
Unknown
Psychotic Disorders
Unknown
Small molecule
Approved
OTHER
ORAL
Gout
Solute carrier family 22 member 12 inhibitor
Small molecule
Approved
OTHER
ORAL
Low Back Pain; Pain; Spasm
Unknown
Small molecule
Approved
Unknown
Unknown
Schizophrenia; Psychotic Disorders
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY
ORAL
Alzheimer Disease; Depression; Depressive Disorder; Depressive Disorder, Major
Monoamine oxidase inhibitor
Small molecule
Approved
OTHER
INJECTION; INTERSTITIAL; INTRAVENOUS
Inflammatory Breast Neoplasms; Arthritis, Rheumatoid; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Head and Neck Neoplasms; Lung Neoplasms; Lymphedema; Melanoma; Breast Neoplasms; Periodontitis; Endometrial Neoplasms; Hirschsprung Disease; Periodontal Diseases; Retinal Perforations; Stomach Neoplasms
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Macular Edema; Scleritis; Cataract; Dry Eye Syndromes; Otitis Externa; Uveitis, Anterior
Unknown
Small molecule
Approved
Unknown
Unknown
Glaucoma
Unknown
Small molecule
Approved
Unknown
Unknown
Glaucoma; Hypertension
Unknown
Small molecule
Approved
OTHER
INTRAMUSCULAR
Hypoglycemia; Insulin Resistance; Postoperative Complications; Hypotension, Orthostatic; Orthostatic Intolerance; Prediabetic State; Amyotrophic Lateral Sclerosis; Blood Coagulation Disorders; Bradycardia; Breast Neoplasms; Heart Arrest; Hemorrhage; Hypospadias; Pneumonia, Ventilator-Associated; Rhinitis, Allergic, Seasonal; Amblyopia; Anisometropia; Dwarfism, Pituitary; Headache; Myopia; Pain; Strabismus; Digestive System Diseases; Mydriasis; Poisoning
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Glaucoma
Acetylcholinesterase inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Depressive Disorder; Migraine Disorders; Complex Regional Pain Syndromes; Neuralgia; Epilepsy, Absence; Irritable Bowel Syndrome; Seizures; Epilepsy
Voltage-gated T-type calcium channel blocker