DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Urinary Tract Infections; Bronchitis, Chronic; Infections; Pharyngitis; Tonsillitis Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER ORAL Cystic Fibrosis; Diabetes Mellitus, Type 2; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infertility, Female; Leukemia, Lymphocytic, Chronic, B-Cell; Non-alcoholic Fatty Liver Disease; Bulimia; Bulimia Nervosa; Depressive Disorder; Endometrial Neoplasms; Hidradenitis Suppurativa; Hyperandrogenism; Metrorrhagia; Osteoporosis; Premenstrual Syndrome; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Migraine Disorders; Neural Tube Defects; Polycystic Ovary Syndrome; Pregnancy; Turner Syndrome; Acne Vulgaris; Neoplasms Estrogen receptor alpha agonist

Small molecule

Approved

OTHER

ORAL

Cystic Fibrosis; Diabetes Mellitus, Type 2; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Infertility, Female; Leukemia, Lymphocytic, Chronic, B-Cell; Non-alcoholic Fatty Liver Disease; Bulimia; Bulimia Nervosa; Depressive Disorder; Endometrial Neoplasms; Hidradenitis Suppurativa; Hyperandrogenism; Metrorrhagia; Osteoporosis; Premenstrual Syndrome; Amenorrhea; Anorexia Nervosa; Bone Diseases, Metabolic; Breast Neoplasms; Dysmenorrhea; Migraine Disorders; Neural Tube Defects; Polycystic Ovary Syndrome; Pregnancy; Turner Syndrome; Acne Vulgaris; Neoplasms

Estrogen receptor alpha agonist


Small molecule Approved OTHER; UROLOGY AND KIDNEY ORAL Aging; Amyotrophic Lateral Sclerosis; Bulbo-Spinal Atrophy, X-Linked; Prostatitis; Severe Acute Respiratory Syndrome; Alopecia; Hypogonadism; Prostatic Neoplasms, Castration-Resistant; Prostatic Hyperplasia; Prostatic Neoplasms Steroid 5-alpha-reductase inhibitor


Protein Approved OTHER; RHEUMATOLOGY SUBCUTANEOUS Endometriosis; Granulomatous Disease, Chronic; Asthma; Blepharitis; Breast Neoplasms; Hearing Loss; HIV Infections; Hypertension, Pulmonary; Knee Injuries; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Sclerosis; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Smoldering Multiple Myeloma; Amyotrophic Lateral Sclerosis; Arthritis, Juvenile; Brain Injuries; Cerebral Hemorrhage; Dermatomyositis; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatigue Syndrome, Chronic; Gout; Heart Failure; Hepatitis, Alcoholic; Hidradenitis Suppurativa; Infections; Labyrinth Diseases; Lymphoma, Follicular; Macrophage Activation Syndrome; Multiple Myeloma; Myocarditis; Myositis, Inclusion Body; Osteoarthritis; Pericarditis; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Sarcoidosis; Still's Disease, Adult-Onset; Uveitis; Familial Mediterranean Fever; Giant Cell Arteritis; Metabolic Syndrome; Mucocutaneous Lymph Node Syndrome; Myocardial Infarction; Severe Acute Respiratory Syndrome; Arthritis, Rheumatoid; Cryopyrin-Associated Periodic Syndromes; Immune System Diseases Interleukin-1 receptor antagonist

Protein

Approved

OTHER; RHEUMATOLOGY

SUBCUTANEOUS

Endometriosis; Granulomatous Disease, Chronic; Asthma; Blepharitis; Breast Neoplasms; Hearing Loss; HIV Infections; Hypertension, Pulmonary; Knee Injuries; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Sclerosis; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Smoldering Multiple Myeloma; Amyotrophic Lateral Sclerosis; Arthritis, Juvenile; Brain Injuries; Cerebral Hemorrhage; Dermatomyositis; Diabetes Mellitus; Diabetes Mellitus, Type 1; Fatigue Syndrome, Chronic; Gout; Heart Failure; Hepatitis, Alcoholic; Hidradenitis Suppurativa; Infections; Labyrinth Diseases; Lymphoma, Follicular; Macrophage Activation Syndrome; Multiple Myeloma; Myocarditis; Myositis, Inclusion Body; Osteoarthritis; Pericarditis; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Sarcoidosis; Still's Disease, Adult-Onset; Uveitis; Familial Mediterranean Fever; Giant Cell Arteritis; Metabolic Syndrome; Mucocutaneous Lymph Node Syndrome; Myocardial Infarction; Severe Acute Respiratory Syndrome; Arthritis, Rheumatoid; Cryopyrin-Associated Periodic Syndromes; Immune System Diseases

Interleukin-1 receptor antagonist


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Constipation; Irritable Bowel Syndrome Serotonin 4 (5-HT4) receptor partial agonist


Protein Approved GASTROINTESTINAL; OTHER INTRAVENOUS Autistic Disorder Secretin receptor agonist


Protein Approved GASTROINTESTINAL; OTHER INJECTION Dyspepsia; Pancreatitis, Chronic; Obesity; Pancreatitis; Schizophrenia; Autistic Disorder Secretin receptor agonist


Small molecule Approved CARDIOVASCULAR; OTHER; RESPIRATORY INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS Raynaud Disease; Diabetic Foot; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis Prostanoid IP receptor agonist

Small molecule

Approved

CARDIOVASCULAR; OTHER; RESPIRATORY

INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS

Raynaud Disease; Diabetic Foot; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis

Prostanoid IP receptor agonist


Protein Approved IMMUNE SYSTEM; OTHER SUBCUTANEOUS; UNKNOWN Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Clostridium Infections; Colonic Neoplasms; Diffuse Intrinsic Pontine Glioma; Multiple Myeloma; Thrombocytopenia; Depressive Disorder; Hepatitis; Hepatitis C; Hepatitis D; HIV Infections; Infections; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Cirrhosis; Melanoma; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Hepatitis B; Hepatitis B, Chronic; Hepatitis C, Chronic Interferon alpha/beta receptor agonist

Protein

Approved

IMMUNE SYSTEM; OTHER

SUBCUTANEOUS; UNKNOWN

Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Clostridium Infections; Colonic Neoplasms; Diffuse Intrinsic Pontine Glioma; Multiple Myeloma; Thrombocytopenia; Depressive Disorder; Hepatitis; Hepatitis C; Hepatitis D; HIV Infections; Infections; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Cirrhosis; Melanoma; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Hepatitis B; Hepatitis B, Chronic; Hepatitis C, Chronic

Interferon alpha/beta receptor agonist


Small molecule Approved CANCER; OTHER INJECTION; INTRAVENOUS Carcinoid Tumor; Digestive System Diseases; Gastrointestinal Stromal Tumors; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Diseases; Lymphoma, T-Cell, Cutaneous; Melanoma; Myelodysplastic Syndromes; Neuroblastoma; Anus Neoplasms; Breast Neoplasms; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma, Follicular; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Adenocarcinoma, Mucinous; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Signet Ring Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Esophageal Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Neoplasms DNA inhibitor

Small molecule

Approved

CANCER; OTHER

INJECTION; INTRAVENOUS

Carcinoid Tumor; Digestive System Diseases; Gastrointestinal Stromal Tumors; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Diseases; Lymphoma, T-Cell, Cutaneous; Melanoma; Myelodysplastic Syndromes; Neuroblastoma; Anus Neoplasms; Breast Neoplasms; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Leukemia-Lymphoma, Adult T-Cell; Lung Neoplasms; Lymphoma, Follicular; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Adenocarcinoma, Mucinous; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Signet Ring Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Esophageal Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Neoplasms

DNA inhibitor


Small molecule Approved OTHER; PEDIATRICS ORAL Albinism; Alkaptonuria; Tyrosinemias 4-hydroxyphenylpyruvate dioxygenase inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL HIV Infections; Bronchiolitis; Crohn Disease; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Tuberculosis; Amebiasis; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Diarrhea Pyruvate:ferredoxin oxidoreductase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL

HIV Infections; Bronchiolitis; Crohn Disease; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Tuberculosis; Amebiasis; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Diarrhea

Pyruvate:ferredoxin oxidoreductase inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Cytomegalovirus Infections; HIV Infections; Hepatitis B, Chronic; Virus Diseases DNA polymerase/reverse transcriptase inhibitor


Small molecule Approved OTHER ORAL Prostatic Neoplasms, Castration-Resistant; HIV Infections; Hepatitis C, Chronic; Hepatitis D; Non-alcoholic Fatty Liver Disease; Aortic Valve Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Metabolic Syndrome; Metabolism, Inborn Errors; Myocardial Infarction; Cardiovascular Diseases; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II Niemann-Pick C1-like protein 1 inhibitor

Small molecule

Approved

OTHER

ORAL

Prostatic Neoplasms, Castration-Resistant; HIV Infections; Hepatitis C, Chronic; Hepatitis D; Non-alcoholic Fatty Liver Disease; Aortic Valve Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Metabolic Syndrome; Metabolism, Inborn Errors; Myocardial Infarction; Cardiovascular Diseases; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II

Niemann-Pick C1-like protein 1 inhibitor


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Diabetes Mellitus, Type 2; Atrial Fibrillation; Breast Neoplasms; Central Serous Chorioretinopathy; Diabetic Nephropathies; Hyperparathyroidism, Primary; Cardiomyopathies; Essential Hypertension; Muscular Dystrophy, Duchenne; Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Stroke Mineralocorticoid receptor antagonist

Small molecule

Approved

CARDIOVASCULAR; OTHER

ORAL

Diabetes Mellitus, Type 2; Atrial Fibrillation; Breast Neoplasms; Central Serous Chorioretinopathy; Diabetic Nephropathies; Hyperparathyroidism, Primary; Cardiomyopathies; Essential Hypertension; Muscular Dystrophy, Duchenne; Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Mineralocorticoid receptor antagonist


Small molecule Approved OTHER INTRAMUSCULAR; ORAL; ORALLY DISINTEGRATING Amphetamine-Related Disorders; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Fragile X Syndrome; Obsessive-Compulsive Disorder; Alcoholism; Alzheimer Disease; Anorexia Nervosa; Anxiety; Child Development Disorders, Pervasive; Dementia; Depression, Postpartum; Stress Disorders, Post-Traumatic; Tourette Syndrome; Aggression; Autistic Disorder; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Psychomotor Agitation; Psychotic Disorders; Schizophrenia Dopamine D2 receptor partial agonist

Small molecule

Approved

OTHER

INTRAMUSCULAR; ORAL; ORALLY DISINTEGRATING

Amphetamine-Related Disorders; Asperger Syndrome; Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Fragile X Syndrome; Obsessive-Compulsive Disorder; Alcoholism; Alzheimer Disease; Anorexia Nervosa; Anxiety; Child Development Disorders, Pervasive; Dementia; Depression, Postpartum; Stress Disorders, Post-Traumatic; Tourette Syndrome; Aggression; Autistic Disorder; Bipolar Disorder; Depressive Disorder; Depressive Disorder, Major; Psychomotor Agitation; Psychotic Disorders; Schizophrenia

Dopamine D2 receptor partial agonist


Small molecule Approved IMMUNE SYSTEM; OTHER INJECTION; INTRAVENOUS; IV (INFUSION); ORAL Asthma; Graft vs Host Disease; Hematologic Neoplasms; HIV Infections; Keratitis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Neutropenia; Aspergillosis, Allergic Bronchopulmonary; Myelodysplastic Syndromes; Candidiasis, Invasive; Leukemia; Leukemia, Myeloid, Acute; Mycoses; Neuroaspergillosis; Aspergillosis; Candidemia; Candidiasis; Fusariosis; Infections Cytochrome P450 51 inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

INJECTION; INTRAVENOUS; IV (INFUSION); ORAL

Asthma; Graft vs Host Disease; Hematologic Neoplasms; HIV Infections; Keratitis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Neutropenia; Aspergillosis, Allergic Bronchopulmonary; Myelodysplastic Syndromes; Candidiasis, Invasive; Leukemia; Leukemia, Myeloid, Acute; Mycoses; Neuroaspergillosis; Aspergillosis; Candidemia; Candidiasis; Fusariosis; Infections

Cytochrome P450 51 inhibitor


Unknown Approved OTHER INTRAPERITONEAL Renal Insufficiency, Chronic; Heart Failure Osmotic agent


Small molecule Approved OTHER ORAL Common Cold; Infections; Respiratory Tract Infections; Cough; Fever; Headache; Sinusitis Unknown


Small molecule Approved OTHER TOPICAL Candidiasis, Vulvovaginal; Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved OTHER ORAL Unknown Voltage-gated L-type calcium channel blocker


Small molecule Approved OTHER INTRAVENOUS; IV (INFUSION) Meningitis; Renal Insufficiency, Chronic; Sepsis; Meningitis, Pneumococcal; Bacteremia; Diabetic Foot; Endocarditis, Bacterial; Gram-Positive Bacterial Infections; Osteomyelitis; Pneumonia, Bacterial; Renal Insufficiency; Skin Diseases; Staphylococcal Infections; Bacterial Infections; Endocarditis; Infections Cell membrane inhibitor


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER SUBCUTANEOUS Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Sarcoma; Fibrous Dysplasia, Polyostotic; Pituitary Diseases; Acromegaly Growth hormone receptor antagonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY ORAL Head and Neck Neoplasms; Muscular Dystrophies; Astrocytoma; Glioblastoma; Heart Failure; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Priapism; Scleroderma, Systemic; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension Phosphodiesterase 5A inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY

ORAL

Head and Neck Neoplasms; Muscular Dystrophies; Astrocytoma; Glioblastoma; Heart Failure; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Priapism; Scleroderma, Systemic; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension

Phosphodiesterase 5A inhibitor


Enzyme Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY INTRAVENOUS Fabry Disease Globotriosylceramide hydrolytic enzyme


Small molecule Approved OTHER ORAL Cystic Fibrosis; HIV Infections; Spastic Paraplegia, Hereditary; Gangliosidoses, GM2; Glycogen Storage Disease; Glycogen Storage Disease Type II; Niemann-Pick Disease, Type C; Sandhoff Disease; Gaucher Disease Ceramide glucosyltransferase inhibitor


Small molecule Approved OTHER ORAL Angioedema; Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria Histamine H1 receptor antagonist


Small molecule Approved OTHER ORAL Hepatitis C; Insulin Resistance; Tuberculosis; Liver Cirrhosis, Biliary; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic; Infections; Severe Acute Respiratory Syndrome; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Small molecule

Approved

CANCER; GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting

Neurokinin 1 receptor antagonist


Protein Approved OTHER INTRAVENOUS Obsessive-Compulsive Disorder; Autistic Disorder Secretin receptor agonist


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY ORAL Asthma; Maxillary Sinusitis; Otitis Media; Otitis Media, Suppurative; Pharyngitis; Scrub Typhus; Tonsillitis; Bacterial Infections; Infections; Pneumonia Bacterial 70S ribosome inhibitor

Antibody

Approved

OTHER; UROLOGY AND KIDNEY

INTRAVENOUS

Desmoplastic Small Round Cell Tumor; Pharyngeal Neoplasms; Renal Insufficiency, Chronic; von Hippel-Lindau Disease; Carcinoma, Merkel Cell; Carcinoma, Pancreatic Ductal; Cystadenoma, Serous; Diabetic Neuropathies; Endometriosis; Inflammatory Breast Neoplasms; Lymphedema; Meningitis, Aseptic; Myeloproliferative Disorders; Neoplasm Metastasis; Neuromyelitis Optica; Pulmonary Veno-Occlusive Disease; Adenocarcinoma, Clear Cell; Adenoma; Adrenal Cortex Neoplasms; Ascites; Astrocytoma; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma; Carcinoma, Islet Cell; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Central Serous Chorioretinopathy; Cholangiocarcinoma; Choriocarcinoma; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fibrosarcoma; Glioma; Granuloma, Lethal Midline; Head and Neck Neoplasms; Hemangiosarcoma; Hemorrhage; Histiocytoma, Benign Fibrous; Hodgkin Disease; Insulinoma; Keloid; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Meningioma; Multiple Myeloma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Oligodendroglioma; Optic Neuropathy, Ischemic; Papilloma; Pinealoma; Pneumonia; Primary Myelofibrosis; Prostatic Neoplasms, Castration-Resistant; Pulmonary Fibrosis; Retroviridae Infections; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Kaposi; Sarcoma, Synovial; Severe Acute Respiratory Syndrome; Sex Cord-Gonadal Stromal Tumors; Small Cell Lung Carcinoma; Somatostatinoma; Spinal Cord Neoplasms; Thymoma; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Trophoblastic Tumor, Placental Site; Urinary Bladder Neoplasms; Vascular Diseases; Vitreous Hemorrhage; Adenocarcinoma; Adenocarcinoma of Lung; Breast Neoplasms; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Signet Ring Cell; Choroiditis; Colorectal Neoplasms, Hereditary Nonpolyposis; Corneal Neovascularization; Diabetic Retinopathy; Fallopian Tube Neoplasms; Gastrointestinal Stromal Tumors; Glaucoma; Gliosarcoma; Inflammation; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Follicular; Macular Degeneration; Macular Edema; Mesothelioma; Myopia; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pleural Effusion; Prostatic Neoplasms; Pterygium; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retinal Detachment; Retinal Diseases; Retinal Vein Occlusion; Retinopathy of Prematurity; Stomach Neoplasms; Telangiectasia, Hereditary Hemorrhagic; Telangiectasis; Uveitis; Uveomeningoencephalitic Syndrome; Wet Macular Degeneration; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Glioblastoma; Neoplasms; Uterine Cervical Neoplasms

Vascular endothelial growth factor A inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL

Renal Insufficiency, Chronic; Cholangitis, Sclerosing; Neoplasms; Persian Gulf Syndrome; Alzheimer Disease; Anemia, Sickle Cell; Breast Neoplasms; Diverticulitis; Dyspepsia; Heart Failure, Systolic; Hepatitis C; HIV Infections; Intestinal Pseudo-Obstruction; Rosacea; Vaginosis, Bacterial; Brain Diseases; Clostridium Infections; Colitis, Collagenous; Crohn Disease; Helicobacter Infections; Hepatitis, Alcoholic; Irritable Bowel Syndrome; Liver Cirrhosis; Parkinson Disease; Peritonitis; Rectal Neoplasms; Diarrhea; Hepatic Encephalopathy; Infections

Bacterial DNA-directed RNA polymerase inhibitor

Small molecule

Approved

EMERGENCY MEDICINE; MUSCULOSKELETAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Essential Tremor; Marijuana Abuse; Tobacco Use Disorder; Carcinoma, Squamous Cell; Cough; Oropharyngeal Neoplasms; Pregnancy; Refractive Errors; Alcoholism; Complex Regional Pain Syndromes; Diabetes Mellitus; Dry Eye Syndromes; Irritable Bowel Syndrome; Nausea; Pancreatitis, Chronic; Pruritus; Urinary Bladder, Overactive; Anxiety; Anxiety Disorders; Breast Neoplasms; Chronic Pain; Dementia; Depressive Disorder; Diabetic Neuropathies; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; Fractures, Bone; Herpes Zoster; Intervertebral Disc Degeneration; Migraine Disorders; Mononeuropathies; Muscle Cramp; Neuralgia, Postherpetic; Neurotic Disorders; Opioid-Related Disorders; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Prostatitis; Radiculopathy; Restless Legs Syndrome; Schizophrenia; Sleep Initiation and Maintenance Disorders; Epilepsy; Fibromyalgia; Neuralgia; Seizures; Spinal Cord Injuries

Voltage-gated calcium channel modulator

Small molecule

Approved

HEMATOLOGY; OTHER

INTRAVENOUS; SUBCUTANEOUS

Brain Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Ependymoma; Esophageal Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Lymphoma, Non-Hodgkin; Myelodysplastic-Myeloproliferative Diseases; Osteosarcoma; Ovarian Neoplasms; Tuberculosis; beta-Thalassemia; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Glioma; Hematologic Neoplasms; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Melanoma; Multiple Myeloma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Anemia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms; Thrombocytopenia

DNA (cytosine-5)-methyltransferase 1 inhibitor