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Therapeutic Area
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
ZAPNOMETINIB
2
Unknown
Investigational
Unknown
Unknown
Severe Acute Respiratory Syndrome
Unknown
ZAPNOMETINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GLYCIDIDAZOLE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GLYCIDIDAZOLE
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C18H23N7O10
Molecular Weight:
497.42
AlogP:
-0.31
PSA:
215.06
HBD:
1.0
HBA:
#RotB:
14.0
Source:
XBD173
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
XBD173
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD5672
2
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Arthritis, Rheumatoid
C-C chemokine receptor type 5 antagonist
AZD5672
×
Maximum Phase:
2
First Approval:
None
UNII:
61XQN688TW
Molecule Type:
Small molecule
Molecular Formula:
C31H43F2N3O5S2
Molecular Weight:
639.83
AlogP:
4.07
PSA:
95.07
HBD:
0.0
HBA:
#RotB:
11.0
Source:
SUFUGOLIX
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Gonadotropin-releasing hormone receptor antagonist
SUFUGOLIX
×
Maximum Phase:
2
First Approval:
None
UNII:
56S17Z6X9M
Molecule Type:
Small molecule
Molecular Formula:
C36H31F2N5O4S
Molecular Weight:
667.74
AlogP:
6.52
PSA:
97.6
HBD:
2.0
HBA:
#RotB:
10.0
Source:
PIRITREXIM
2
Small molecule
Investigational
Unknown
Unknown
Urethral Neoplasms; Urinary Bladder Neoplasms
Dihydrofolate reductase inhibitor
PIRITREXIM
×
Maximum Phase:
2
First Approval:
None
UNII:
MK2A783ZUT
Molecule Type:
Small molecule
Molecular Formula:
C17H19N5O2
Molecular Weight:
325.37
AlogP:
2.11
PSA:
109.17
HBD:
2.0
HBA:
#RotB:
4.0
Source:
ETHION
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ETHION
×
Maximum Phase:
2
First Approval:
None
UNII:
2TI07NO12Y
Molecule Type:
Small molecule
Molecular Formula:
C9H22O4P2S4
Molecular Weight:
384.49
AlogP:
5.01
PSA:
36.92
HBD:
0.0
HBA:
#RotB:
12.0
Source:
FLORBENAZINE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FLORBENAZINE
×
Maximum Phase:
2
First Approval:
None
UNII:
K5GDY88W5X
Molecule Type:
Small molecule
Molecular Formula:
C21H32FNO3
Molecular Weight:
365.49
AlogP:
3.76
PSA:
41.93
HBD:
1.0
HBA:
#RotB:
7.0
Source:
CDP-860
2
Antibody
Investigational
Unknown
Unknown
Unknown
Platelet-derived growth factor receptor beta inhibitor
CDP-860
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TOMUZOTUXIMAB
2
Antibody
Investigational
Unknown
Unknown
Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
TOMUZOTUXIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
5P637IXG16
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
KETOPROFEN SODIUM
2
Small molecule
Investigational
Unknown
Unknown
Muscular Diseases
Unknown
KETOPROFEN SODIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
5R10M39KS7
Molecule Type:
Small molecule
Molecular Formula:
C16H13NaO3
Molecular Weight:
276.27
AlogP:
3.11
PSA:
54.37
HBD:
1.0
HBA:
#RotB:
4.0
Source:
DUSIGITUMAB
2
Antibody
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Neoplasms; Breast Neoplasms
Insulin-like growth factor II inhibitor
DUSIGITUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
0Z70DT5PRX
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ABT-510
2
Protein
Investigational
Unknown
Unknown
Brain Neoplasms; Head and Neck Neoplasms; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Hodgkin Disease; Lymphoma, Non-Hodgkin; Melanoma; Sarcoma
Unknown
ABT-510
×
Maximum Phase:
2
First Approval:
None
UNII:
CRR8E37XOB
Molecule Type:
Protein
Molecular Formula:
C46H83N13O11
Molecular Weight:
994.25
AlogP:
-2.4
PSA:
358.05
HBD:
11.0
HBA:
#RotB:
30.0
Source:
NNC126-0083
2
Protein
Investigational
Unknown
Unknown
Unknown
Unknown
NNC126-0083
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TIPEPIDINE
2
Small molecule
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Cough; Depressive Disorder
Unknown
TIPEPIDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
2260ZP67IT
Molecule Type:
Small molecule
Molecular Formula:
C15H17NS2
Molecular Weight:
275.44
AlogP:
4.34
PSA:
3.24
HBD:
0.0
HBA:
#RotB:
2.0
Source:
OT-551
2
Small molecule
Investigational
Unknown
Unknown
Macular Degeneration
Unknown
OT-551
×
Maximum Phase:
2
First Approval:
None
UNII:
DZ02S3A31N
Molecule Type:
Small molecule
Molecular Formula:
C13H23NO3
Molecular Weight:
241.33
AlogP:
2.35
PSA:
49.77
HBD:
1.0
HBA:
#RotB:
2.0
Source:
URELUMAB
2
Antibody
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Gliosarcoma; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms; Pancreatic Neoplasms; Leukemia; Melanoma
Tumor necrosis factor receptor superfamily member 9 agonist
URELUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
230902QLLC
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ME-401
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
ME-401
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
APRATASTAT
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid
Unknown
APRATASTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
C6BZ5263BJ
Molecule Type:
Small molecule
Molecular Formula:
C17H22N2O6S2
Molecular Weight:
414.51
AlogP:
0.45
PSA:
116.17
HBD:
3.0
HBA:
#RotB:
5.0
Source:
THYMOSIN BETA 4
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
THYMOSIN BETA 4
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
INECALCITOL
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute
Vitamin D receptor agonist
INECALCITOL
×
Maximum Phase:
2
First Approval:
None
UNII:
05FZV98342
Molecule Type:
Small molecule
Molecular Formula:
C26H40O3
Molecular Weight:
400.6
AlogP:
4.76
PSA:
60.69
HBD:
3.0
HBA:
#RotB:
3.0
Source:
SELTOREXANT
2
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Liver Diseases; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Depressive Disorder, Major
Orexin receptor 2 antagonist
SELTOREXANT
×
Maximum Phase:
2
First Approval:
None
UNII:
AIS8N3O50B
Molecule Type:
Small molecule
Molecular Formula:
C21H22FN7O
Molecular Weight:
407.45
AlogP:
2.02
PSA:
80.04
HBD:
0.0
HBA:
#RotB:
3.0
Source:
INCAGN01876
2
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
INCAGN01876
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ABITUZUMAB
2
Antibody
Investigational
Unknown
Unknown
Colorectal Neoplasms; Ovarian Neoplasms; Lung Diseases, Interstitial; Prostatic Neoplasms, Castration-Resistant; Scleroderma, Systemic
Integrin alpha-V/beta-1 inhibitor
ABITUZUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
724QD330RD
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
APOLIZUMAB
2
Antibody
Investigational
Unknown
Unknown
Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma
Human leukocyte antigen DR beta chain inhibitor
APOLIZUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
G88KCP51RE
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PF-04217329
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
PF-04217329
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OC000459
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Dermatitis, Atopic; Eosinophilic Esophagitis; Rhinitis, Allergic, Seasonal
G protein-coupled receptor 44 antagonist
OC000459
×
Maximum Phase:
2
First Approval:
None
UNII:
04XB9TB8OL
Molecule Type:
Small molecule
Molecular Formula:
C21H17FN2O2
Molecular Weight:
348.38
AlogP:
4.31
PSA:
55.12
HBD:
1.0
HBA:
#RotB:
4.0
Source:
JNJ-39393406
2
Small molecule
Investigational
Unknown
Unknown
Schizophrenia; Depressive Disorder; Smoking Cessation
Neuronal acetylcholine receptor protein alpha-7 subunit positive allosteric modulator
JNJ-39393406
×
Maximum Phase:
2
First Approval:
None
UNII:
T930SOU82P
Molecule Type:
Small molecule
Molecular Formula:
C19H18F2N6O3
Molecular Weight:
416.39
AlogP:
2.88
PSA:
94.4
HBD:
1.0
HBA:
#RotB:
6.0
Source:
LANIQUIDAR
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Unknown
LANIQUIDAR
×
Maximum Phase:
2
First Approval:
None
UNII:
K3FRN4DDOY
Molecule Type:
Small molecule
Molecular Formula:
C37H36N4O3
Molecular Weight:
584.72
AlogP:
6.49
PSA:
69.48
HBD:
0.0
HBA:
#RotB:
7.0
Source:
PRX-08066
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Serotonin 2b (5-HT2b) receptor antagonist
PRX-08066
×
Maximum Phase:
2
First Approval:
None
UNII:
92E9B7675Y
Molecule Type:
Small molecule
Molecular Formula:
C23H21ClFN5O4S
Molecular Weight:
517.97
AlogP:
4.43
PSA:
64.84
HBD:
1.0
HBA:
#RotB:
4.0
Source:
ZANIDATAMAB
2
Antibody
Investigational
Unknown
Unknown
Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms
Unknown
ZANIDATAMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
Z20OC92TDI
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NEBICAPONE
2
Small molecule
Investigational
Unknown
Unknown
Parkinson Disease
Catechol O-methyltransferase inhibitor
NEBICAPONE
×
Maximum Phase:
2
First Approval:
None
UNII:
NM2KXJ990T
Molecule Type:
Small molecule
Molecular Formula:
C14H11NO5
Molecular Weight:
273.24
AlogP:
2.43
PSA:
100.67
HBD:
2.0
HBA:
#RotB:
4.0
Source:
LITRONESIB
2
Small molecule
Investigational
Unknown
Unknown
Leukemia; Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms
Kinesin-like protein 1 inhibitor
LITRONESIB
×
Maximum Phase:
2
First Approval:
None
UNII:
6611F8KYCV
Molecule Type:
Small molecule
Molecular Formula:
C23H37N5O4S2
Molecular Weight:
511.71
AlogP:
2.42
PSA:
119.97
HBD:
3.0
HBA:
#RotB:
8.0
Source:
.ALPHA.-R-LIPOIC ACID CHOLINE ESTER CHLORIDE
2
Small molecule
Investigational
Unknown
Unknown
Presbyopia
Unknown
.ALPHA.-R-LIPOIC ACID CHOLINE ESTER CHLORIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
6HBG94710Z
Molecule Type:
Small molecule
Molecular Formula:
C13H26ClNO2S2
Molecular Weight:
327.94
AlogP:
2.95
PSA:
26.3
HBD:
0.0
HBA:
#RotB:
8.0
Source:
ARTEMISONE
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ARTEMISONE
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
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Molecular Formula
Molecular Weight
ALogP
PSA